IL78661A - Bone targeted inhibitors of carbonic anhydrase and methods for the preparation thereof - Google Patents

Bone targeted inhibitors of carbonic anhydrase and methods for the preparation thereof

Info

Publication number
IL78661A
IL78661A IL8678661A IL7866186A IL78661A IL 78661 A IL78661 A IL 78661A IL 8678661 A IL8678661 A IL 8678661A IL 7866186 A IL7866186 A IL 7866186A IL 78661 A IL78661 A IL 78661A
Authority
IL
Israel
Prior art keywords
preparation
carbonic anhydrase
methods
bone
targeted inhibitors
Prior art date
Application number
IL8678661A
Other languages
English (en)
Other versions
IL78661A0 (en
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of IL78661A0 publication Critical patent/IL78661A0/xx
Publication of IL78661A publication Critical patent/IL78661A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL8678661A 1985-05-02 1986-05-02 Bone targeted inhibitors of carbonic anhydrase and methods for the preparation thereof IL78661A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73087385A 1985-05-03 1985-05-03

Publications (2)

Publication Number Publication Date
IL78661A0 IL78661A0 (en) 1986-08-31
IL78661A true IL78661A (en) 1992-08-18

Family

ID=24937140

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8678661A IL78661A (en) 1985-05-02 1986-05-02 Bone targeted inhibitors of carbonic anhydrase and methods for the preparation thereof

Country Status (10)

Country Link
EP (1) EP0201057B1 (ja)
JP (1) JP2578098B2 (ja)
AT (1) ATE82854T1 (ja)
DE (1) DE3687181T2 (ja)
DK (1) DK201486A (ja)
ES (1) ES8802468A1 (ja)
GR (1) GR861167B (ja)
IE (1) IE59801B1 (ja)
IL (1) IL78661A (ja)
PT (1) PT82499B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0341961A3 (en) * 1988-05-09 1990-06-20 Merck & Co. Inc. Polymalonic acids as boneaffinity agents
JPH0778024B2 (ja) * 1988-10-14 1995-08-23 藤沢薬品工業株式会社 医薬化合物とジホスホン酸誘導体の結合体を含有する医薬用製剤
US4990523A (en) * 1989-06-19 1991-02-05 A. H. Robins Company, Incorporated Treatment of chronic inflammatory joint disease with arylsulfonamides
US5183815A (en) * 1991-01-22 1993-02-02 Merck & Co., Inc. Bone acting agents
EP0496520A1 (en) * 1991-01-22 1992-07-29 Merck & Co. Inc. Novel bone acting agents
JP3377856B2 (ja) * 1993-03-25 2003-02-17 イスクラ産業株式会社 骨吸収抑制・骨形成促進化合物
EP0688787A4 (en) * 1993-12-29 1996-04-17 Iskra Industry Co Ltd MEDICAL COMPOSITION FOR INHIBITING BONE RESORPTION AND ACCELERATING OSTEOGENESIS
US5880111A (en) * 1995-06-07 1999-03-09 Farcasiu; Dan Therapeutic derivations of diphosphonates
JP2001511811A (ja) 1997-02-13 2001-08-14 ボーン ケア インターナショナル インコーポレイテッド ビタミンｄ化合物の標的治療放出
DE19828068C2 (de) * 1998-06-24 2003-12-18 Peter Dietsch Mittel zur spezifischen Hemmung osteoklastärer Knochenresorption
US6214381B1 (en) 1998-09-08 2001-04-10 Effcon, Inc. Methazolamide composition and method of use
AU4682700A (en) * 1999-04-30 2000-11-17 Research Corporation Technologies, Inc. Bone targeting agents for osteoporosis
US6436386B1 (en) * 2000-11-14 2002-08-20 Shearwater Corporation Hydroxyapatite-targeting poly (ethylene glycol) and related polymers
US7829074B2 (en) 2001-10-18 2010-11-09 Nektar Therapeutics Hydroxypatite-targeting poly(ethylene glycol) and related polymers
US9980946B1 (en) 2017-01-25 2018-05-29 Effcon Laboratories, Inc. Extended release methazolamide formulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666897A (en) * 1983-12-29 1987-05-19 Research Foundation Of State University Inhibition of mammalian collagenolytic enzymes by tetracyclines
US4704383A (en) * 1983-12-29 1987-11-03 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
ATE114473T1 (de) * 1984-04-30 1994-12-15 Procter & Gamble Ausrüstung für die verwendung bei der behandlung von osteoporose.

Also Published As

Publication number Publication date
IL78661A0 (en) 1986-08-31
EP0201057A2 (en) 1986-11-12
IE861148L (en) 1986-11-02
DK201486A (da) 1986-11-04
DK201486D0 (da) 1986-05-01
EP0201057B1 (en) 1992-12-02
JP2578098B2 (ja) 1997-02-05
DE3687181D1 (de) 1993-01-14
GR861167B (en) 1986-09-30
EP0201057A3 (en) 1989-10-18
ES555118A0 (es) 1988-07-16
ES8802468A1 (es) 1988-07-16
DE3687181T2 (de) 1993-04-15
ATE82854T1 (de) 1992-12-15
IE59801B1 (en) 1994-04-06
PT82499B (pt) 1988-10-14
JPS6226256A (ja) 1987-02-04
PT82499A (en) 1986-06-01

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Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void