IL78352A0 - Aminopropanol derivatives,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Aminopropanol derivatives,processes for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- IL78352A0 IL78352A0 IL78352A IL7835286A IL78352A0 IL 78352 A0 IL78352 A0 IL 78352A0 IL 78352 A IL78352 A IL 78352A IL 7835286 A IL7835286 A IL 7835286A IL 78352 A0 IL78352 A0 IL 78352A0
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- group
- straight
- replaced
- chained
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- MXZROAOUCUVNHX-UHFFFAOYSA-N 2-Aminopropanol Chemical class CCC(N)O MXZROAOUCUVNHX-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 125000004417 unsaturated alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Measurement Of Force In General (AREA)
- Professional, Industrial, Or Sporting Protective Garments (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853512627 DE3512627A1 (de) | 1985-04-06 | 1985-04-06 | Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL78352A0 true IL78352A0 (en) | 1986-07-31 |
Family
ID=6267498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL78352A IL78352A0 (en) | 1985-04-06 | 1986-03-31 | Aminopropanol derivatives,processes for the preparation thereof and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4863949A (cs) |
| EP (1) | EP0200915B1 (cs) |
| JP (1) | JPS61236758A (cs) |
| AT (1) | ATE46688T1 (cs) |
| AU (1) | AU5552886A (cs) |
| CS (1) | CS223886A2 (cs) |
| DD (1) | DD247214A5 (cs) |
| DE (2) | DE3512627A1 (cs) |
| DK (1) | DK155186A (cs) |
| ES (1) | ES8705371A1 (cs) |
| FI (1) | FI861410A7 (cs) |
| GR (1) | GR860900B (cs) |
| HU (1) | HU198444B (cs) |
| IL (1) | IL78352A0 (cs) |
| ZA (1) | ZA862407B (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3705622A1 (de) * | 1987-02-21 | 1988-09-01 | Boehringer Mannheim Gmbh | Neue amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| US5229412A (en) * | 1988-03-25 | 1993-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds |
| US5428061A (en) * | 1988-09-15 | 1995-06-27 | Schwarz Pharma Ag | Organic nitrates and method for their preparation |
| JP2628756B2 (ja) * | 1988-09-15 | 1997-07-09 | シュバルツファルマ アクチェンゲゼルシャフト | 新規有機ニトレート及びそれらの製造方法 |
| NL8802276A (nl) * | 1988-09-15 | 1990-04-02 | Cedona Pharm Bv | Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat. |
| DE3836021A1 (de) * | 1988-10-22 | 1990-05-03 | Boehringer Mannheim Gmbh | Arzneimittel enthaltend nitroxyalkylamine mit amidfunktion und verfahren zur herstellung dieser verbindungen |
| DE4011505C2 (de) * | 1990-04-10 | 1995-01-12 | Sanol Arznei Schwarz Gmbh | Nitratoalkancarbonsäure-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| US5284872A (en) * | 1989-09-12 | 1994-02-08 | Schwarz Pharma Ag | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof |
| US5925658A (en) * | 1995-03-02 | 1999-07-20 | Sankyo Company, Limited | Optically active thiazolidinone derivative |
| DE19616020A1 (de) * | 1996-04-23 | 1997-10-30 | Huels Chemische Werke Ag | Neue Polyamine sowie ein Verfahren zu ihrer Herstellung |
| US20050137191A1 (en) * | 1996-06-04 | 2005-06-23 | Thatcher Gregory R. | Nitrate esters and their use for mitigating cellular damage |
| US6310052B1 (en) | 1996-06-04 | 2001-10-30 | Queen's University At Kingston | Nitrate esters and their use for neurological conditions |
| US5807847A (en) * | 1996-06-04 | 1998-09-15 | Queen's University At Kingston | Nitrate esters |
| US20070010571A1 (en) * | 2003-08-20 | 2007-01-11 | Nitromed, Inc. | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use |
| ES2285549T3 (es) * | 2003-12-02 | 2007-11-16 | Nicox S.A. | Derivados nitroxxi de carvedidol y otros beta bloqueantes utilizados como medicamentos antihipertensores. |
| AU2005304770A1 (en) * | 2004-11-08 | 2006-05-18 | Nicox S.A. | Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders |
| CN115010631B (zh) * | 2021-03-05 | 2024-12-06 | 中国石油化工股份有限公司 | 一种从天然气中脱除硫化氢及硫醇的化合物及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL163775C (nl) * | 1967-12-18 | 1980-10-15 | Boehringer Sohn Ingelheim | Werkwijze ter bereiding van farmaceutische preparaten met beta-receptoren blokkerende werking, alsmede werkwijze ter bereiding van 1-(cyaanfenoxy)-2-hydroxy-3-(sec.alkylamino) propaanderivaten. |
| SE379196B (cs) * | 1971-06-24 | 1975-09-29 | Sandoz Ag | |
| GB1455116A (en) * | 1972-12-15 | 1976-11-10 | Ici Ltd | Pharmaceutical compositions |
| ZA742728B (en) * | 1973-05-08 | 1975-04-30 | Simes | Pharmaceutical composition for the treatment of coronaric ailments |
| GB1508208A (en) * | 1975-12-05 | 1978-04-19 | Ici Ltd | Amide derivatives |
| GB1540463A (en) * | 1976-10-07 | 1979-02-14 | Ici Ltd | Alkanolamine derivatives |
| DE2805404A1 (de) * | 1978-02-09 | 1979-08-16 | Merck Patent Gmbh | 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung |
| CH636856A5 (en) * | 1978-07-17 | 1983-06-30 | Sandoz Ag | 4-(3-Aminopropoxy)indole derivatives, their preparation and medicines containing them |
| GB2044251B (en) * | 1978-12-01 | 1983-03-23 | Bristol Myers Co | Phenoxypropanolamine derivatives |
| JPS5677257A (en) * | 1979-11-29 | 1981-06-25 | Teikoku Chem Ind Corp Ltd | Drug having beta-blocking activity |
| JPS56113748A (en) * | 1980-02-13 | 1981-09-07 | Kowa Co | Aminoethanol derivative and its preparation |
| DE3426419A1 (de) * | 1984-07-18 | 1986-01-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte |
-
1985
- 1985-04-06 DE DE19853512627 patent/DE3512627A1/de not_active Withdrawn
-
1986
- 1986-03-31 IL IL78352A patent/IL78352A0/xx unknown
- 1986-04-01 AT AT86104392T patent/ATE46688T1/de not_active IP Right Cessation
- 1986-04-01 DE DE8686104392T patent/DE3665862D1/de not_active Expired
- 1986-04-01 FI FI861410A patent/FI861410A7/fi not_active Application Discontinuation
- 1986-04-01 AU AU55528/86A patent/AU5552886A/en not_active Abandoned
- 1986-04-01 EP EP86104392A patent/EP0200915B1/de not_active Expired
- 1986-04-01 CS CS862238A patent/CS223886A2/cs unknown
- 1986-04-02 ZA ZA862407A patent/ZA862407B/xx unknown
- 1986-04-03 HU HU861421A patent/HU198444B/hu not_active IP Right Cessation
- 1986-04-03 ES ES553684A patent/ES8705371A1/es not_active Expired
- 1986-04-04 DD DD86288793A patent/DD247214A5/de not_active IP Right Cessation
- 1986-04-04 JP JP61076827A patent/JPS61236758A/ja active Pending
- 1986-04-04 GR GR860900A patent/GR860900B/el unknown
- 1986-04-04 DK DK155186A patent/DK155186A/da not_active IP Right Cessation
-
1987
- 1987-09-21 US US07/098,719 patent/US4863949A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI861410A7 (fi) | 1986-10-07 |
| DK155186A (da) | 1986-10-07 |
| DD247214A5 (de) | 1987-07-01 |
| ZA862407B (en) | 1986-11-26 |
| DK155186D0 (da) | 1986-04-04 |
| EP0200915A1 (de) | 1986-11-12 |
| GR860900B (en) | 1986-08-04 |
| AU5552886A (en) | 1986-10-09 |
| DE3665862D1 (en) | 1989-11-02 |
| ES8705371A1 (es) | 1987-05-16 |
| FI861410A0 (fi) | 1986-04-01 |
| ATE46688T1 (de) | 1989-10-15 |
| DE3512627A1 (de) | 1986-10-09 |
| JPS61236758A (ja) | 1986-10-22 |
| HUT40617A (en) | 1987-01-28 |
| US4863949A (en) | 1989-09-05 |
| EP0200915B1 (de) | 1989-09-27 |
| ES553684A0 (es) | 1987-05-16 |
| CS223886A2 (en) | 1989-02-10 |
| HU198444B (en) | 1989-10-30 |
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