IL75901A - 8-(2(1,4-benzodioxan-2-yl alkylamino)alkyl)-8-glutarimide derivatives and antianxiety and antihypertensive compositions containing them - Google Patents
8-(2(1,4-benzodioxan-2-yl alkylamino)alkyl)-8-glutarimide derivatives and antianxiety and antihypertensive compositions containing themInfo
- Publication number
- IL75901A IL75901A IL75901A IL7590185A IL75901A IL 75901 A IL75901 A IL 75901A IL 75901 A IL75901 A IL 75901A IL 7590185 A IL7590185 A IL 7590185A IL 75901 A IL75901 A IL 75901A
- Authority
- IL
- Israel
- Prior art keywords
- antianxiety
- benzodioxan
- alkylamino
- alkyl
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63539484A | 1984-07-30 | 1984-07-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL75901A0 IL75901A0 (en) | 1985-12-31 |
| IL75901A true IL75901A (en) | 1988-11-15 |
Family
ID=24547629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL75901A IL75901A (en) | 1984-07-30 | 1985-07-24 | 8-(2(1,4-benzodioxan-2-yl alkylamino)alkyl)-8-glutarimide derivatives and antianxiety and antihypertensive compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0170213B1 (xx) |
| JP (1) | JPH0631222B2 (xx) |
| KR (1) | KR880002625B1 (xx) |
| AR (1) | AR241161A1 (xx) |
| AT (1) | ATE49409T1 (xx) |
| AU (1) | AU578962B2 (xx) |
| CA (1) | CA1244418A (xx) |
| DE (1) | DE3575301D1 (xx) |
| DK (1) | DK163304C (xx) |
| ES (1) | ES8604151A1 (xx) |
| FI (1) | FI84178C (xx) |
| GR (1) | GR851835B (xx) |
| HU (1) | HU197002B (xx) |
| IE (1) | IE58073B1 (xx) |
| IL (1) | IL75901A (xx) |
| NO (1) | NO159089C (xx) |
| NZ (1) | NZ212856A (xx) |
| PT (1) | PT80859B (xx) |
| ZA (1) | ZA855563B (xx) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4704389A (en) * | 1986-03-05 | 1987-11-03 | Merrell Dow Pharmaceuticals Inc. | Aromatic omega-alkyl-imino-tetrahydro-6H-1,3-thiazin-6-one derivatives |
| US4696927A (en) * | 1986-03-05 | 1987-09-29 | Merrell Dow Pharmaceuticals Inc. | 4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives |
| US4748182A (en) * | 1986-03-05 | 1988-05-31 | Merrell Dow Pharmaceuticals Inc. | Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents |
| ZA871449B (en) * | 1986-03-05 | 1987-08-20 | Merrell Dow Pharmaceutical Inc. | Aromatic omega-alkylimino-tetrahydro-6h-1,3-thiazin-6-one derivatives |
| US5258379A (en) * | 1990-05-04 | 1993-11-02 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with n-arylpiperazines |
| US5158956A (en) * | 1990-05-04 | 1992-10-27 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with benzodioxanes |
| US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| EP0564520A1 (en) * | 1990-12-24 | 1993-10-13 | Merrell Dow Pharmaceuticals Inc. | Use of certain glutarimide derivatives in the treatment of depression and mania |
| MX9201991A (es) * | 1991-05-02 | 1992-11-01 | Jonh Wyeth & Brother Limited | Derivados de piperazina y procedimiento para su preparacion. |
| WO1992020338A1 (en) * | 1991-05-10 | 1992-11-26 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of glaucoma |
| US5126367A (en) * | 1991-06-21 | 1992-06-30 | American Home Products Corporation | Psychotropic benzodioxan derivatives |
| US5221745A (en) * | 1991-06-21 | 1993-06-22 | American Home Products Corp. | Psychotropic piperidinylmethyl benzodioxans |
| US5126366A (en) * | 1991-06-21 | 1992-06-30 | American Home Products Corporation | Aminophenoxyalkyl derivatives of benzodioxan |
| US5134140A (en) * | 1991-06-21 | 1992-07-28 | American Home Products Corporation | Psychotropic benzofuran derivatives |
| US5189171A (en) * | 1991-06-21 | 1993-02-23 | American Home Products Corporation | Antipsychotic benzodioxan derivatives |
| US5182292A (en) * | 1991-06-21 | 1993-01-26 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
| US5212170A (en) * | 1991-06-21 | 1993-05-18 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
| US5166367A (en) * | 1991-06-21 | 1992-11-24 | American Home Products Corporation | Antipsychotic benzodioxan derivatives |
| FR2678617B1 (fr) * | 1991-07-01 | 1995-01-20 | Adir | Nouveau procede de synthese d'enantiomeres de derives du 3-amino chromane. |
| FR2681325B1 (fr) * | 1991-09-16 | 1993-12-17 | Fabre Medicament Pierre | Derives de l'aminomethyl-4 piperidine, leur preparation et leur application en therapeutique. |
| JP3136206B2 (ja) * | 1991-10-22 | 2001-02-19 | 中外製薬株式会社 | ベンゾジオキサン誘導体 |
| ZA931343B (en) * | 1992-03-06 | 1993-09-24 | Akzo Nv | 1,4-dioxino(2,3-b)pyridine derivatives. |
| US5235055A (en) * | 1992-09-02 | 1993-08-10 | American Home Products Corporation | Antipsychotic quinoline derivatives of benzodioxanmethylamine |
| US5245051A (en) * | 1992-09-03 | 1993-09-14 | American Home Products Corporation | Antipsychotic chroman derivatives of benzodioxanmethylamine |
| GB9305672D0 (en) * | 1993-03-19 | 1993-05-05 | Wyeth John & Brother Ltd | Amide derivatives |
| US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
| US5631017A (en) * | 1993-03-26 | 1997-05-20 | Beth Israel Deaconess Medical Center, Inc. | Topical application of buspirone for treatment of pathological conditions associated with immune responses |
| US5637314A (en) * | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
| JP4690314B2 (ja) * | 2004-05-17 | 2011-06-01 | ダイセル化学工業株式会社 | Ｎ−ヒドロキシ環状イミド化合物の製造法 |
| EP2236511A4 (en) | 2007-12-21 | 2011-04-13 | Alla Chem Llc | LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF |
| KR102022154B1 (ko) * | 2016-11-24 | 2019-09-18 | 한양대학교 산학협력단 | MBD2-p66α(GATAD2A)의 상호작용을 억제하는 화합물을 포함하는 암 전이 억제 및 암 질환 예방 및 치료용 조성물 |
-
1985
- 1985-07-23 AR AR301063A patent/AR241161A1/es active
- 1985-07-23 ZA ZA855563A patent/ZA855563B/xx unknown
- 1985-07-23 CA CA000487290A patent/CA1244418A/en not_active Expired
- 1985-07-24 GR GR851835A patent/GR851835B/el unknown
- 1985-07-24 ES ES545558A patent/ES8604151A1/es not_active Expired
- 1985-07-24 PT PT80859A patent/PT80859B/pt not_active IP Right Cessation
- 1985-07-24 NZ NZ212856A patent/NZ212856A/en unknown
- 1985-07-24 IL IL75901A patent/IL75901A/xx not_active IP Right Cessation
- 1985-07-25 EP EP85109362A patent/EP0170213B1/en not_active Expired - Lifetime
- 1985-07-25 AU AU45353/85A patent/AU578962B2/en not_active Ceased
- 1985-07-25 AT AT85109362T patent/ATE49409T1/de not_active IP Right Cessation
- 1985-07-25 DE DE8585109362T patent/DE3575301D1/de not_active Expired - Fee Related
- 1985-07-25 IE IE187085A patent/IE58073B1/en not_active IP Right Cessation
- 1985-07-26 HU HU852846A patent/HU197002B/hu not_active IP Right Cessation
- 1985-07-26 FI FI852922A patent/FI84178C/fi not_active IP Right Cessation
- 1985-07-29 DK DK344085A patent/DK163304C/da not_active IP Right Cessation
- 1985-07-29 KR KR1019850005433A patent/KR880002625B1/ko not_active IP Right Cessation
- 1985-07-29 JP JP60166059A patent/JPH0631222B2/ja not_active Expired - Lifetime
- 1985-07-29 NO NO852994A patent/NO159089C/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3575301D1 (de) | 1990-02-15 |
| NZ212856A (en) | 1988-05-30 |
| CA1244418A (en) | 1988-11-08 |
| ZA855563B (en) | 1986-05-28 |
| JPS61246180A (ja) | 1986-11-01 |
| NO159089C (no) | 1988-11-30 |
| AU578962B2 (en) | 1988-11-10 |
| ES8604151A1 (es) | 1986-01-16 |
| AR241161A2 (es) | 1991-12-30 |
| FI852922L (fi) | 1986-01-31 |
| FI84178B (fi) | 1991-07-15 |
| EP0170213A1 (en) | 1986-02-05 |
| HU197002B (en) | 1989-02-28 |
| DK163304B (da) | 1992-02-17 |
| ES545558A0 (es) | 1986-01-16 |
| DK344085D0 (da) | 1985-07-29 |
| DK163304C (da) | 1992-07-06 |
| EP0170213B1 (en) | 1990-01-10 |
| FI852922A0 (fi) | 1985-07-26 |
| AR241161A1 (es) | 1991-12-30 |
| PT80859B (pt) | 1987-09-18 |
| KR880002625B1 (ko) | 1988-12-07 |
| NO159089B (no) | 1988-08-22 |
| JPH0631222B2 (ja) | 1994-04-27 |
| IE58073B1 (en) | 1993-06-30 |
| DK344085A (da) | 1986-01-31 |
| KR860001103A (ko) | 1986-02-22 |
| AU4535385A (en) | 1986-02-06 |
| IE851870L (en) | 1986-01-30 |
| FI84178C (fi) | 1991-10-25 |
| NO852994L (no) | 1986-01-31 |
| IL75901A0 (en) | 1985-12-31 |
| GR851835B (xx) | 1985-12-02 |
| HUT38338A (en) | 1986-05-28 |
| PT80859A (en) | 1985-08-01 |
| ATE49409T1 (de) | 1990-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH1 | Patent not in force | ||
| HC | Change of name of proprietor(s) |
Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC. |