IL75739A - Phenyloxy(or thio)methyl-3-fluoroalkylamines and pharmaceutical compositions comprising them - Google Patents

Phenyloxy(or thio)methyl-3-fluoroalkylamines and pharmaceutical compositions comprising them

Info

Publication number
IL75739A
IL75739A IL75739A IL7573985A IL75739A IL 75739 A IL75739 A IL 75739A IL 75739 A IL75739 A IL 75739A IL 7573985 A IL7573985 A IL 7573985A IL 75739 A IL75739 A IL 75739A
Authority
IL
Israel
Prior art keywords
fluoroalkylamines
phenyloxy
thio
methyl
pharmaceutical compositions
Prior art date
Application number
IL75739A
Other languages
English (en)
Other versions
IL75739A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL75739A0 publication Critical patent/IL75739A0/xx
Publication of IL75739A publication Critical patent/IL75739A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/42—Halogenated unsaturated alcohols acyclic
    • C07C33/423—Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL75739A 1984-07-13 1985-07-08 Phenyloxy(or thio)methyl-3-fluoroalkylamines and pharmaceutical compositions comprising them IL75739A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63055684A 1984-07-13 1984-07-13

Publications (2)

Publication Number Publication Date
IL75739A0 IL75739A0 (en) 1985-11-29
IL75739A true IL75739A (en) 1988-07-31

Family

ID=24527644

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75739A IL75739A (en) 1984-07-13 1985-07-08 Phenyloxy(or thio)methyl-3-fluoroalkylamines and pharmaceutical compositions comprising them

Country Status (20)

Country Link
EP (1) EP0168013B1 (fr)
JP (1) JPS61257952A (fr)
KR (1) KR900008113B1 (fr)
AR (1) AR240043A1 (fr)
AT (1) ATE32711T1 (fr)
AU (1) AU575973B2 (fr)
CA (1) CA1256453A (fr)
DE (1) DE3561723D1 (fr)
DK (1) DK166878C (fr)
ES (1) ES545111A0 (fr)
FI (1) FI84057C (fr)
GB (1) GB2162518B (fr)
HU (1) HU195181B (fr)
IE (1) IE58305B1 (fr)
IL (1) IL75739A (fr)
NO (1) NO161313C (fr)
NZ (1) NZ212675A (fr)
PH (1) PH21647A (fr)
PT (1) PT80805B (fr)
ZA (1) ZA855101B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE71933T1 (de) * 1985-12-05 1992-02-15 Merrell Dow Pharma Nichtaromatische fluoralkylamin-mao-inhibitoren.
GB2202222B (en) * 1987-03-16 1991-03-27 American Home Prod Fluorooxirane carboxylates
US4822812A (en) * 1987-05-21 1989-04-18 Merrell Dow Pharmaceuticals Inc. β-(Fluoromethylene)-5-hydroxytryptophan and derivatives and their use as prodrugs for MAO inhibition
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5059714A (en) * 1988-02-25 1991-10-22 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5252608A (en) * 1988-02-25 1993-10-12 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5488188A (en) * 1994-09-29 1996-01-30 Merrell Dow Pharmaceuticals Inc. Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof
EP2004166A2 (fr) * 2006-03-31 2008-12-24 La Jolla Pharmaceutical Company Inhibiteurs d'adhérence médiée par l'amine oxydase sensible aux semi-carbazides (ssao) et la vap-1 utilisés dans le traitement et la prévention de maladies
CN107266332B (zh) * 2012-05-02 2020-07-24 勃林格殷格翰国际有限公司 Ssao的取代的3-卤代烯丙基胺抑制剂及其用途
WO2024044813A1 (fr) * 2022-08-29 2024-03-07 Pharmaxis Ltd. Nouveaux inhibiteurs sélectifs de lysyl oxydases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1027611A (en) * 1962-01-04 1966-04-27 May & Baker Ltd Phenoxy- and phenylthio-alkylamines and acid addition salts thereof
US3205136A (en) * 1962-12-24 1965-09-07 Smith Kline French Lab Antidepressant phenyloxyalkylamines
US3513198A (en) * 1965-10-22 1970-05-19 Hoffmann La Roche Aryloxy- and arylthio-acetylenic amines and the salts thereof
CH480306A (de) * 1966-06-03 1969-10-31 Ciba Geigy Verfahren zur Herstellung von schwefelhaltigen Aminen

Also Published As

Publication number Publication date
GB8517454D0 (en) 1985-08-14
NO161313B (no) 1989-04-24
GB2162518A (en) 1986-02-05
PT80805A (en) 1985-08-01
CA1256453A (fr) 1989-06-27
JPH0530823B2 (fr) 1993-05-11
DK166878C (da) 1993-12-13
AU575973B2 (en) 1988-08-11
DK320585D0 (da) 1985-07-12
ZA855101B (en) 1986-05-28
IE58305B1 (en) 1993-09-08
FI852748L (fi) 1986-01-14
GB2162518B (en) 1987-11-18
NO161313C (no) 1989-08-02
FI84057C (fi) 1991-10-10
EP0168013A1 (fr) 1986-01-15
JPS61257952A (ja) 1986-11-15
PH21647A (en) 1988-01-13
PT80805B (pt) 1987-09-18
IL75739A0 (en) 1985-11-29
DK320585A (da) 1986-01-14
AR240043A1 (es) 1990-01-31
ES8603809A1 (es) 1986-01-01
DE3561723D1 (de) 1988-04-07
HUT38604A (en) 1986-06-30
NO852810L (no) 1986-01-14
ES545111A0 (es) 1986-01-01
NZ212675A (en) 1988-02-29
AU4466085A (en) 1986-01-16
IE851746L (en) 1986-01-13
KR900008113B1 (ko) 1990-10-31
ATE32711T1 (de) 1988-03-15
FI84057B (fi) 1991-06-28
KR860001048A (ko) 1986-02-22
FI852748A0 (fi) 1985-07-11
HU195181B (en) 1988-04-28
EP0168013B1 (fr) 1988-03-02
DK166878B (da) 1993-07-26

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.