IL75733A - 5-phenyl-1,6-naphthyridin-2(1h)-ones,their preparation and pharmaceutical compositions containing them - Google Patents
5-phenyl-1,6-naphthyridin-2(1h)-ones,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL75733A IL75733A IL75733A IL7573385A IL75733A IL 75733 A IL75733 A IL 75733A IL 75733 A IL75733 A IL 75733A IL 7573385 A IL7573385 A IL 7573385A IL 75733 A IL75733 A IL 75733A
- Authority
- IL
- Israel
- Prior art keywords
- naphthyridin
- ones
- phenyl
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/630,810 US4560691A (en) | 1984-07-13 | 1984-07-13 | 5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL75733A0 IL75733A0 (en) | 1985-11-29 |
| IL75733A true IL75733A (en) | 1988-07-31 |
Family
ID=24528649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL75733A IL75733A (en) | 1984-07-13 | 1985-07-05 | 5-phenyl-1,6-naphthyridin-2(1h)-ones,their preparation and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4560691A (fr) |
| EP (1) | EP0168037B1 (fr) |
| JP (1) | JPS6140286A (fr) |
| KR (1) | KR870001089B1 (fr) |
| AR (1) | AR242388A1 (fr) |
| AT (1) | ATE50259T1 (fr) |
| AU (1) | AU584103B2 (fr) |
| DE (1) | DE3575926D1 (fr) |
| DK (1) | DK318985A (fr) |
| ES (1) | ES8706151A1 (fr) |
| FI (1) | FI852765L (fr) |
| GR (1) | GR851677B (fr) |
| IL (1) | IL75733A (fr) |
| MX (1) | MX161361A (fr) |
| NO (1) | NO852677L (fr) |
| NZ (1) | NZ212647A (fr) |
| PH (1) | PH21844A (fr) |
| PT (1) | PT80809B (fr) |
| ZA (1) | ZA855280B (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4532247A (en) * | 1983-08-08 | 1985-07-30 | Sterling Drug Inc. | 5-(Hydroxyalkyl or alkanoyloxymethyl)-1,6-naphthyridin-2(1H)-one and cardiotonic use thereof |
| US4567186A (en) * | 1985-01-14 | 1986-01-28 | Sterling Drug Inc. | 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor |
| NZ214837A (en) * | 1985-01-28 | 1988-10-28 | Sterling Drug Inc | 5-substituted 1,6 naphthyridin-2(1h)-ones |
| DE3840341A1 (de) * | 1988-11-30 | 1990-06-07 | Basf Ag | Verfahren zur herstellung von 1-nitroanthrachinon-2-carbonsaeure |
| US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| DK1333833T3 (da) | 2000-10-23 | 2011-12-12 | Glaxosmithkline Llc | Ny trisubstitueret 8H-pyridol[2,3-d]pyrimidin-7-on-forbindelse til behandling af CSBP/RK/p38-kinnasemedierede sygdomme |
| CA2482022A1 (fr) * | 2002-04-19 | 2003-10-30 | Smithkline Beecham Corporation | Nouveaux composes |
| US7550480B2 (en) * | 2003-02-14 | 2009-06-23 | Smithkline Beecham Corporation | Compounds |
| MY145281A (en) | 2005-03-25 | 2012-01-13 | Glaxo Group Ltd | Novel compounds |
| WO2006110298A2 (fr) * | 2005-03-25 | 2006-10-19 | Glaxo Group Limited | Nouveaux composes |
| AR053450A1 (es) * | 2005-03-25 | 2007-05-09 | Glaxo Group Ltd | Derivados de 3,4-dihidro-pirimido(4,5-d)pirimidin-2-(1h)-ona 1,5,7 trisustituidos como inhibidores de la quinasa p38 |
| CA2603163A1 (fr) * | 2005-03-25 | 2006-10-05 | Glaxo Group Limited | Procede de preparation de derives pyrido[2,3-d]pyrimidin-7-one et 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one |
| CN105218388B (zh) * | 2015-10-26 | 2017-07-11 | 西北农林科技大学 | β‑羰基烯胺类化合物及作为制备植物病原菌抗菌剂的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4412077A (en) * | 1982-03-15 | 1983-10-25 | Sterling Drug Inc. | Process for preparing 5-(lower-alkanoyl)-6-(lower-alkyl)-2(1H)-pyridinone |
| US4415580A (en) * | 1982-08-02 | 1983-11-15 | Sterling Drug Inc. | Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same |
-
1984
- 1984-07-13 US US06/630,810 patent/US4560691A/en not_active Expired - Fee Related
-
1985
- 1985-07-03 NO NO852677A patent/NO852677L/no unknown
- 1985-07-04 NZ NZ212647A patent/NZ212647A/xx unknown
- 1985-07-05 GR GR851677A patent/GR851677B/el unknown
- 1985-07-05 IL IL75733A patent/IL75733A/xx unknown
- 1985-07-09 DE DE8585108538T patent/DE3575926D1/de not_active Expired - Fee Related
- 1985-07-09 AT AT85108538T patent/ATE50259T1/de not_active IP Right Cessation
- 1985-07-09 MX MX8266A patent/MX161361A/es unknown
- 1985-07-09 EP EP85108538A patent/EP0168037B1/fr not_active Expired - Lifetime
- 1985-07-10 AU AU44747/85A patent/AU584103B2/en not_active Ceased
- 1985-07-10 JP JP15215885A patent/JPS6140286A/ja active Pending
- 1985-07-11 AR AR85300954A patent/AR242388A1/es active
- 1985-07-11 PH PH32510A patent/PH21844A/en unknown
- 1985-07-12 ES ES545139A patent/ES8706151A1/es not_active Expired
- 1985-07-12 KR KR1019850004976A patent/KR870001089B1/ko not_active IP Right Cessation
- 1985-07-12 PT PT80809A patent/PT80809B/pt unknown
- 1985-07-12 ZA ZA855280A patent/ZA855280B/xx unknown
- 1985-07-12 DK DK318985A patent/DK318985A/da unknown
- 1985-07-12 FI FI852765A patent/FI852765L/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US4560691A (en) | 1985-12-24 |
| EP0168037A3 (en) | 1986-03-26 |
| FI852765L (fi) | 1986-01-14 |
| JPS6140286A (ja) | 1986-02-26 |
| PT80809A (en) | 1985-08-01 |
| IL75733A0 (en) | 1985-11-29 |
| NO852677L (no) | 1986-01-14 |
| GR851677B (fr) | 1985-11-26 |
| PT80809B (en) | 1987-01-12 |
| ATE50259T1 (de) | 1990-02-15 |
| EP0168037B1 (fr) | 1990-02-07 |
| EP0168037A2 (fr) | 1986-01-15 |
| KR870001089B1 (ko) | 1987-06-04 |
| DE3575926D1 (de) | 1990-03-15 |
| KR860001109A (ko) | 1986-02-22 |
| ZA855280B (en) | 1986-02-26 |
| ES8706151A1 (es) | 1987-06-01 |
| DK318985A (da) | 1986-01-14 |
| NZ212647A (en) | 1988-07-28 |
| ES545139A0 (es) | 1987-06-01 |
| DK318985D0 (da) | 1985-07-12 |
| AU4474785A (en) | 1986-01-16 |
| FI852765A0 (fi) | 1985-07-12 |
| MX161361A (es) | 1990-09-18 |
| AU584103B2 (en) | 1989-05-18 |
| AR242388A1 (es) | 1993-03-31 |
| PH21844A (en) | 1988-03-17 |
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