IL74422A - Antifungal dermatological solutions comprising certain imidazole derivatives of the class 1-(beta-aryl)ethyl-imidazole ethers - Google Patents

Antifungal dermatological solutions comprising certain imidazole derivatives of the class 1-(beta-aryl)ethyl-imidazole ethers

Info

Publication number
IL74422A
IL74422A IL74422A IL7442285A IL74422A IL 74422 A IL74422 A IL 74422A IL 74422 A IL74422 A IL 74422A IL 7442285 A IL7442285 A IL 7442285A IL 74422 A IL74422 A IL 74422A
Authority
IL
Israel
Prior art keywords
imidazole
antifungal
beta
aryl
ethyl
Prior art date
Application number
IL74422A
Other languages
English (en)
Other versions
IL74422A0 (en
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IL74422A0 publication Critical patent/IL74422A0/xx
Publication of IL74422A publication Critical patent/IL74422A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL74422A 1984-02-23 1985-02-22 Antifungal dermatological solutions comprising certain imidazole derivatives of the class 1-(beta-aryl)ethyl-imidazole ethers IL74422A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/583,081 US4912124A (en) 1984-02-23 1984-02-23 Antifungal dermatological solution

Publications (2)

Publication Number Publication Date
IL74422A0 IL74422A0 (en) 1985-05-31
IL74422A true IL74422A (en) 1988-12-30

Family

ID=24331614

Family Applications (1)

Application Number Title Priority Date Filing Date
IL74422A IL74422A (en) 1984-02-23 1985-02-22 Antifungal dermatological solutions comprising certain imidazole derivatives of the class 1-(beta-aryl)ethyl-imidazole ethers

Country Status (8)

Country Link
US (1) US4912124A (de)
EP (1) EP0156507B1 (de)
AT (1) ATE55906T1 (de)
CA (1) CA1241603A (de)
DE (1) DE3579337D1 (de)
IE (1) IE57948B1 (de)
IL (1) IL74422A (de)
ZA (1) ZA851374B (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820724A (en) * 1986-03-31 1989-04-11 University Of Southern California Dual phase solvent carrier system
FR2609714A1 (fr) * 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de derives antifongiques imidazoles
FR2613227B1 (fr) * 1987-04-01 1990-12-28 Oreal Compositions pharmaceutiques a base de nitrate de miconazole ou de nitrate d'econazole dans le traitement des infections fongiques des ongles
US5087620A (en) * 1990-05-17 1992-02-11 Bristol-Myers Squibb Co. Controlled dermal penetration enhancement using imidazoles
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US6005001A (en) * 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
US5461068A (en) * 1993-09-29 1995-10-24 Corwood Laboratories, Inc. Imidazole derivative tincture and method of manufacture
US5514698A (en) * 1994-03-21 1996-05-07 Ortho Pharmaceutical Corporation Antifungal vaginal cream composition
JPH10504291A (ja) * 1994-07-22 1998-04-28 ジー．ディー．サール アンド カンパニー 自己乳化性ドラッグデリバリーシステム
US6075056A (en) * 1997-10-03 2000-06-13 Penederm, Inc. Antifungal/steroid topical compositions
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US7244703B2 (en) 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
HU0104790D0 (en) * 2001-11-08 2002-01-28 Human Rt Pharmaceutical combinations for topical application
GB2384985A (en) * 2002-02-12 2003-08-13 Barry Siberry Cures and preventions for fungal infections in humans and animals
KR20100055542A (ko) * 2002-06-25 2010-05-26 애크럭스 디디에스 피티와이 리미티드 비정질 약학적 조성물을 이용한 경피전달속도의 제어
US20060140984A1 (en) 2002-10-25 2006-06-29 Foamix Ltd. Cosmetic and pharmaceutical foam
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
WO2004037197A2 (en) * 2002-10-24 2004-05-06 Goldstein Jay A Antifungal formulations
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
WO2004108114A2 (en) * 2003-03-31 2004-12-16 Dinesh Shantilal Patel Anti-fungal composition and a process for its manufacture
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
CN101829319A (zh) 2003-12-08 2010-09-15 Cpex药品公司 用于胰岛素治疗的药用组合物及方法
WO2005115336A2 (en) * 2004-05-15 2005-12-08 Collegium Pharmaceutical, Inc. Sprayable formulations for the treatment of acute inflammatory skin conditions
WO2007054818A2 (en) * 2005-05-09 2007-05-18 Foamix Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20090215888A1 (en) * 2006-03-02 2009-08-27 Singh Jagat Topical nail formulation
US20070249546A1 (en) * 2006-04-22 2007-10-25 Sawaya Assad S Ophthalmic and related aqueous solutions containing antifungal agents, uses therefor and methods for preparing them
US8413435B2 (en) * 2006-06-13 2013-04-09 Wescast Industries, Inc. Exhaust manifolds including heat shield assemblies
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
WO2009090558A2 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
AU2010302350B2 (en) 2009-10-02 2015-06-18 Journey Medical Corporation Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
NZ613167A (en) * 2010-12-16 2015-09-25 Univ Texas Azole pharmaceutical formulations for parenteral administration and methods for preparing and using the same as treatment of diseases sensitive to azole compounds
US9364433B2 (en) 2011-04-28 2016-06-14 Borje S. Andersson Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
MX363386B (es) 2013-10-03 2019-03-20 Dow Pharmaceutical Sciences Formulaciones de efinaconazol estabilizadas.
CN105848719A (zh) 2013-11-22 2016-08-10 道尔医药科学公司 抗感染的方法、组合物和装置
US20170064956A1 (en) * 2015-11-14 2017-03-09 Park Eugene Garnes, JR. Medisox: Disposable Medicated Athlete's Foot Fungal Socks
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
US3989815A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Novel N-bis-azacyclopentan-2-onyl alkanes
JPS5815909A (ja) * 1981-07-22 1983-01-29 Toko Yakuhin Kogyo Kk 抗真菌外用剤
DE3202602A1 (de) * 1982-01-27 1983-08-04 Bayer Ag, 5090 Leverkusen Antimykotisches mittel

Also Published As

Publication number Publication date
IL74422A0 (en) 1985-05-31
EP0156507A1 (de) 1985-10-02
US4912124A (en) 1990-03-27
CA1241603A (en) 1988-09-06
ATE55906T1 (de) 1990-09-15
EP0156507B1 (de) 1990-08-29
IE57948B1 (en) 1993-05-19
ZA851374B (en) 1986-09-24
IE850442L (en) 1985-08-23
DE3579337D1 (de) 1990-10-04

Similar Documents

Publication Publication Date Title
IL74422A (en) Antifungal dermatological solutions comprising certain imidazole derivatives of the class 1-(beta-aryl)ethyl-imidazole ethers
CA2260185A1 (en) Hormone replacement therapy drug formulations for topical application to the skin
HK68085A (en) Preparations containing methylsulfonylmethane and method of purification
EP0727427A4 (de) Antibacterielles, antipilz- und antiviren-mittel
DK1248613T3 (da) Clonidinpræparater
CA2119636A1 (en) Low pH Aqueous Cosmetic Gel Containing Non-Ionic Polyacrylamide Derivatives
CA2081269A1 (en) Penetration enhancement of topically applied formulations
DE69005398D1 (de) Topisch kosmetisch anzuwendende depolymerisierte Nukleinsäuren enthaltende Arzneizubereitungen.
EP0535237A4 (en) Composition for relieving skin irritation and external preparation for percutaneous adminstration containing the same
ES2137125B1 (es) La utilizacion de la sal de zinc del acido glicirretico en preparados contra el acne y las composiciones que contienen dicha sal.
GB2010679A (en) Fungicidal combination and its use and formulations
GB1288641A (de)
DE59100466D1 (de) Alkohol enthaltende wässrige gelartige phospholipidzusammensetzung, ihre verwendung und topische zubereitungen, die diese enthalten.
AU4307993A (en) Topical application composition
IE810489L (en) Composition for topical application
ATE44233T1 (de) Fungizide aerosol-loesung.
IE43886L (en) Antifungal compositions
PT1207861E (pt) Tratamento de infeccoes fungicas utilizando um meio de crescimento fungico
IE45516L (en) 2-(4'-thiazolyl) benzimidazole complex
ES8601690A1 (es) Un procedimiento para la obtencion de preparados del bifanazol con elevada liberacion del producto actuvo
TR200000890T2 (tr) Topik ilacın üretilmesi için -amino levülozik asidin kullanılması
Smith Topical antifungal agents
KR900016130A (ko) 2-피리딜메틸티오 유도체 및 궤양 치료제
ECSP972226A (es) Derivado analgesico antiinflamatorio no ulcerogenico de clonixina
MX9201491A (es) Producto para el tratamiento de verrugas (fibroma pendulo), alopecia, arrugas, araeata local y universal, herpes y hongos de toda clase en la piel

Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void
KB Patent renewed
EXP Patent expired