IL74365A - 17beta-(n-t.-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one and pharmaceutical compositions containing it - Google Patents
17beta-(n-t.-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one and pharmaceutical compositions containing itInfo
- Publication number
- IL74365A IL74365A IL74365A IL7436585A IL74365A IL 74365 A IL74365 A IL 74365A IL 74365 A IL74365 A IL 74365A IL 7436585 A IL7436585 A IL 7436585A IL 74365 A IL74365 A IL 74365A
- Authority
- IL
- Israel
- Prior art keywords
- 5alpha
- 17beta
- androst
- butylcarbamoyl
- aza
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL86924A IL86924A (en) | 1984-02-27 | 1985-02-18 | 17beta-acyl-4-aza-5alpha-androst-1-en-3-ones and pharmaceutical compositions containing them |
IL86924A IL86924A0 (en) | 1984-02-27 | 1988-06-30 | 17beta-acyl-4-aza-5alpha-androst-1-en-3-ones and pharmaceutical compositions containing them |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58406184A | 1984-02-27 | 1984-02-27 | |
US58406284A | 1984-02-27 | 1984-02-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL74365A0 IL74365A0 (en) | 1985-05-31 |
IL74365A true IL74365A (en) | 1990-07-26 |
Family
ID=27078980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL74365A IL74365A (en) | 1984-02-27 | 1985-02-18 | 17beta-(n-t.-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one and pharmaceutical compositions containing it |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0155096B1 (pt) |
JP (1) | JPH0193600A (pt) |
KR (1) | KR900001206B1 (pt) |
AU (4) | AU584321B2 (pt) |
CA (1) | CA1314541C (pt) |
CY (1) | CY1553A (pt) |
DE (2) | DE3573429D1 (pt) |
DK (1) | DK166704B1 (pt) |
ES (1) | ES8702430A1 (pt) |
GR (1) | GR850483B (pt) |
HK (1) | HK63090A (pt) |
IE (2) | IE58058B1 (pt) |
IL (1) | IL74365A (pt) |
NL (1) | NL930005I2 (pt) |
NZ (1) | NZ211145A (pt) |
PT (1) | PT80010B (pt) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571817A (en) * | 1984-02-27 | 1996-11-05 | Merck & Co., Inc. | Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones] |
US5049562A (en) * | 1984-02-27 | 1991-09-17 | Merck & Co., Inc. | 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α-reductase inhibitors |
US5138063A (en) * | 1984-02-27 | 1992-08-11 | Merck & Co., Inc. | 17β-methoxycarbonyl-4-aza-androsten-1-en-3-ones |
US5120742A (en) * | 1984-02-27 | 1992-06-09 | Merck & Co., Inc. | 17 β-acyl-4-aza-5 α-androst-1-ene-3-ones as 5 α-reductase inhibitors |
US5151429A (en) * | 1984-02-27 | 1992-09-29 | Merck & Co., Inc. | 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α reductase inhibitors |
JPS62201896A (ja) * | 1986-02-28 | 1987-09-05 | Shiseido Co Ltd | 多毛症治療剤 |
EP0271219B1 (en) * | 1986-11-20 | 1992-07-29 | Merck & Co. Inc. | Topical pharmaceutical composition containing 17-beta-methoxycarbonyl-4-methyl-4-aza-5-alpha-androst-1-en-3-one |
US4845104A (en) * | 1986-11-20 | 1989-07-04 | Merck & Co., Inc. | Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones |
US4888336A (en) * | 1987-01-28 | 1989-12-19 | Smithkline Beckman Corporation | Steroid 5-alpha-reductase inhibitors |
DE3888378T2 (de) * | 1987-04-03 | 1994-09-29 | Merck & Co Inc | Behandlung von Prostatacarcinoma mit 17-beta-n-monosubstituierten-Carbamoyl-4-aza-5-alpha-Androst-1-en-3-onen. |
EP0285382B1 (en) * | 1987-04-03 | 1994-04-13 | Merck & Co. Inc. | Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones |
NZ225100A (en) * | 1987-06-29 | 1991-09-25 | Merck & Co Inc | Reaction of steroids (including 4-azasteroids) with a silylating agent in the presence of a quinone to introduce a delta' double bond and silylated intermediates |
US5084574A (en) * | 1988-04-18 | 1992-01-28 | Merck & Co., Inc. | Dehydrogenation process |
US5116983A (en) * | 1988-04-18 | 1992-05-26 | Merck & Co., Inc. | Dehydrogenation process intermediates |
US5237061A (en) * | 1988-10-31 | 1993-08-17 | Merck & Co., Inc. | Methods of synthesizing benign prostatic hypertropic agents and their intermediates |
CA2023157A1 (en) * | 1989-08-21 | 1991-02-22 | Gary H. Rasmusson | 17 beta-acyl-4-aza-5 alpha-androst-1-ene-3-ones as 5 alpha-reductase inhibitors |
US5021575A (en) * | 1989-11-13 | 1991-06-04 | Merck & Co., Inc. | Method for introducing a 1,2 double bond into azasteroids |
GB9002922D0 (en) * | 1990-02-09 | 1990-04-04 | Erba Carlo Spa | 17 beta-substituted-4-aza-5 alpha-androstan-3-one derivatives and process for their preparation |
EP0462664A3 (en) * | 1990-06-20 | 1992-11-25 | Merck & Co. Inc. | Specific 17beta-thiobenzoyl-4-aza-5alpha-androst-1-en-3-ones as antiandrogenic agents |
US5162332A (en) * | 1990-06-20 | 1992-11-10 | Merck & Co., Inc. | Selected 17 β-polyaroyl-4-aza-5 α-androst-1-en-3-ones as steroidal reductase inhibitors |
EP0462665A3 (en) * | 1990-06-20 | 1993-06-30 | Merck & Co. Inc. | Selected 17beta-polyaroyl-4-aza-5alpha-androst-1-en-3-ones as steroidal reductase inhibitors |
EP0462662A3 (en) * | 1990-06-20 | 1992-08-19 | Merck & Co. Inc. | 17beta-n-monosubstituted adamantyl/norbornanyl carbamoyl-4-aza-5alpha-androst-1-en-3-ones and androstan-3-ones |
US5098908A (en) * | 1990-06-20 | 1992-03-24 | Merck & Co., Inc. | 17β-hydroxybenzoyl-4-aza-5α-androst-1-en-3-ones as testosterone reductase inhibitors |
US5151430A (en) * | 1990-06-20 | 1992-09-29 | Merck & Co., Inc. | Specific 17β-thiobenzoyl-4-aza-5α-androst-1-en-3-ones as antiandrogen agents |
US5061802A (en) * | 1990-06-20 | 1991-10-29 | Merck & Co. Inc. | 17β-aminobenzoyl-4-aza-5α-androst-1-en-3-ones as benign prostatic hypertrophy agents |
US5091380A (en) * | 1990-06-28 | 1992-02-25 | Merck & Co., Inc. | N-monosubstituted adamantyl/norbornanyl 17β-carbamides of 3-carboxy-androst-3,5-dienes as testosterone 5α-reductase inhibitors |
US5091534A (en) * | 1990-08-27 | 1992-02-25 | Merck & Co., Inc. | Trialkylsilyl trifluoromethanesulfonate mediated α-methylenic carbon functionalization of 4-AZA-5α-androstan-3-one steroids |
US5120847A (en) * | 1990-08-27 | 1992-06-09 | Merck & Co., Inc. | Process for iodinating or brominating the α-methylenic carbon of a secondary amide |
US5061801A (en) * | 1990-09-24 | 1991-10-29 | Merck & Co., Inc. | Intermediate for making 3-oxo-4-aza-androst-1-ene 17β-ketones |
CA2050824A1 (en) * | 1990-09-24 | 1992-03-25 | John M. Williams | Process for making 3-oxo-4-aza-androst-1-ene 17-.beta.-ketones |
US5061803A (en) * | 1990-09-24 | 1991-10-29 | Merck & Co., Inc. | Process for making 17-beta alkanoyl 3-oxo-4-aza-5-α-androst-1-enes |
IE76452B1 (en) * | 1990-10-29 | 1997-10-22 | Sankyo Co | Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use |
NZ241979A (en) * | 1991-03-20 | 1996-01-26 | Merck & Co Inc | Treatment of benign prostatic hyperplasia using 5alpha-reductase inhibitor and an alpha1-adrenergic recepter blocker |
GB9115676D0 (en) * | 1991-07-19 | 1991-09-04 | Erba Carlo Spa | Process for the preparation of 17 beta substituted-4-aza-5 alpha-androstan-3-one derivatives |
US5304562A (en) * | 1991-10-09 | 1994-04-19 | Ciba-Geigy Corporation | 17β-substituted Aza-androstane derivatives |
EP0547687A1 (en) * | 1991-12-18 | 1993-06-23 | Merck & Co. Inc. | 17B-N-Substituted adamantyl/norbonanyl carbamoyl-4-aza-5a-and-rost-1-en-3-ones and androstan-3 ones |
JPH07502511A (ja) * | 1991-12-20 | 1995-03-16 | グラクソ、インコーポレーテッド | 5‐α‐テストステロンレダクターゼ阻害剤 |
EP0725074A3 (en) * | 1992-04-20 | 1996-11-20 | Sankyo Co | Compounds for use, therefore, intermediates for the preparation of androst-3,5-diene-3-carboxy derivatives |
US5698720A (en) * | 1992-04-20 | 1997-12-16 | Sankyo Company, Limited | Steroid derivatives |
EP0649306B1 (en) * | 1992-05-20 | 2001-01-10 | Merck & Co. Inc. | Ester derivatives of 4-aza-steroids |
US5237064A (en) * | 1992-05-20 | 1993-08-17 | Merck & Co., Inc. | Process for producing 7β-substituted-aza-5αandrostan-3-ones |
CA2135167A1 (en) * | 1992-05-20 | 1993-11-25 | Donald W. Graham | New 17-ester, amide, and ketone derivatives of 3-oxo-4- azasteroids as 5a-reductase inhibitors |
ES2148229T3 (es) * | 1992-05-20 | 2000-10-16 | Merck & Co Inc | Eteres y tioeteres en la posicion 17 de 4-aza-esteroides. |
ATE183193T1 (de) * | 1992-05-20 | 1999-08-15 | Merck & Co Inc | 17-amino-substituierte 4-azasteroide als 5-alpha- reductase inhibitoren |
JPH07508035A (ja) * | 1992-05-20 | 1995-09-07 | メルク エンド カンパニー インコーポレーテッド | 4−アザステロイド5α−レダクターゼ阻害剤 |
RU94046044A (ru) * | 1992-05-20 | 1996-10-10 | Мерк Энд Ко. | Новые 7 бета -замещенные 4-аза- 5 альфа -холестан-оны в качестве ингибиторов 5 альфа -редуктазы, фармацевтическая композиция на их основе, способ ее получения |
US5710275A (en) * | 1992-05-20 | 1998-01-20 | Merck & Co., Inc. | 7β-substituted-4-aza-5α-androstan-3-ones as 5α-reductase inhibitors |
WO1993023039A1 (en) * | 1992-05-20 | 1993-11-25 | Merck & Co., Inc. | Substituted 4-aza-5a-androstan-ones as 5a-reductase inhibitors |
UA35589C2 (uk) * | 1992-05-21 | 2001-04-16 | Андорешерш Інк. | ІНГІБІТОРИ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ІНГІБУВАННЯ АКТИВНОСТІ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ |
GB9216284D0 (en) * | 1992-07-31 | 1992-09-16 | Erba Carlo Spa | Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives |
GB9216329D0 (en) * | 1992-07-31 | 1992-09-16 | Erba Carlo Spa | 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives |
US5302589A (en) * | 1992-08-07 | 1994-04-12 | Glaxo, Inc. | Heterocyclic inhibitors of 5-α-testosterone reductase |
HU212459B (en) * | 1992-10-02 | 1996-06-28 | Richter Gedeon Vegyeszet | Process for producing new 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them |
US5278159A (en) * | 1992-10-06 | 1994-01-11 | Merck & Co., Inc. | Aryl ester derivatives of 3-oxo-4-aza-androstane 17-β-carboxylates as 5-α-reductase inhibitors |
US5468860A (en) | 1992-11-19 | 1995-11-21 | Merck & Co., Inc. | New finasteride processes |
US5359071A (en) * | 1993-03-12 | 1994-10-25 | Merck & Co., Inc. | 15-substituted 4-azasteroids |
AU6413594A (en) * | 1993-03-24 | 1994-10-11 | Merck & Co., Inc. | Substituted 3-phenanthridinone derivatives as 5alpha-reductase inhibitors |
DK0705272T3 (da) * | 1993-06-24 | 2002-05-27 | Richter Gedeon Vegyeszet | Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater |
JP3325026B2 (ja) * | 1993-06-28 | 2002-09-17 | メルク エンド カンパニー インコーポレーテッド | 4−アザ−プレグナン5α−レダクターゼアイソザイム1阻害剤 |
US5438061A (en) * | 1993-07-16 | 1995-08-01 | Merck & Co., Inc. | 7-substituted-δ4-6-azasteroid derivatives as 5α-reductase inhibitors |
TW369521B (en) * | 1993-09-17 | 1999-09-11 | Smithkline Beecham Corp | Androstenone derivative |
US5547957A (en) * | 1993-10-15 | 1996-08-20 | Merck & Co., Inc. | Method of treating androgenic alopecia with 5-α reductase inhibitors |
TW382595B (en) * | 1993-10-15 | 2000-02-21 | Merck & Co Inc | Pharmaceutical composition for use in arresting and reversing androgenic alopecia |
ATE175420T1 (de) * | 1993-10-21 | 1999-01-15 | Merck & Co Inc | 16-substituierte-4-aza-androstan-5-alpha- reduktase-isozym-i-inhibitoren |
GB9415178D0 (en) * | 1994-07-28 | 1994-09-21 | Erba Carlo Spa | 4-azasteroids with side-chain fluoroketones |
US5541322A (en) * | 1994-10-14 | 1996-07-30 | Glaxo Wellcome Inc. | Synthesis of 6-azaandrostenones |
US5595996A (en) * | 1994-10-25 | 1997-01-21 | Merck & Co., Inc. | 7-substituted 4-aza cholanic acid derivatives and their use |
US5656613A (en) * | 1995-01-04 | 1997-08-12 | Merck & Co., Inc. | Treatment of hyperandrogenic conditions |
GB0026876D0 (en) * | 2000-11-03 | 2000-12-20 | Glaxo Group Ltd | Process |
WO2003020311A1 (fr) * | 2001-08-28 | 2003-03-13 | Fujisawa Pharmaceutical Co., Ltd. | Remedes contre les maladies de la peau |
RS92304A (en) | 2002-04-24 | 2006-10-27 | Boehringer Ingelheim Pharma Gmbh. & Co.Kg. | Pharmaceutical combination for the treatment of benign prostatic hyperplasia or for long-term preservation of acute urinary retention |
HU227117B1 (en) | 2002-05-10 | 2010-07-28 | Richter Gedeon Nyrt | Process for dehydrogenation of aza-androstane compounds |
CN1314241C (zh) * | 2002-09-27 | 2007-05-02 | 华为技术有限公司 | 在城域网相同虚容器映射通道内传送不同用户数据的方法 |
KR100508019B1 (ko) | 2003-07-19 | 2005-08-17 | 한미약품 주식회사 | 고순도 1-안드로스텐 유도체의 제조 방법 |
EP1824495A2 (en) | 2004-12-03 | 2007-08-29 | ProteoSys AG | Finasteride, dutasteride and related compounds for preventing/treating neurologically-associated disorders |
EP2050436A1 (en) | 2007-12-21 | 2009-04-22 | Siegfried Generics International AG | Pharmaceutical composition containing dutasteride |
CN104292293B (zh) * | 2014-09-17 | 2016-04-06 | 广东众生药业股份有限公司 | 一种度他雄胺杂质i的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3285918A (en) * | 1962-04-18 | 1966-11-15 | Norman J Doorenbos | 1', 4', 5', 6'-tetrahydropyrimidino[a-4, 3]-4-aza-5-cholestene |
ZA791752B (en) * | 1978-04-13 | 1980-11-26 | Merck & Co Inc | 4-aza-17 beta -substituted-5 alpha -androstan-3-ones useful as 5 alpha -reductase inhibitors |
AU527030B2 (en) * | 1978-04-13 | 1983-02-10 | Merck & Co., Inc. | 4-aza-17-substituted-5a-androstan-3-ones |
US4377584A (en) * | 1978-04-13 | 1983-03-22 | Merck & Co., Inc. | 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors |
US4220775A (en) * | 1979-03-15 | 1980-09-02 | Merck & Co., Inc. | Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors |
GB8505862D0 (en) * | 1985-03-07 | 1985-04-11 | Erba Farmitalia | Steroidic 5alpha-reductase inhibitors |
-
1985
- 1985-02-18 IL IL74365A patent/IL74365A/xx not_active IP Right Cessation
- 1985-02-18 NZ NZ211145A patent/NZ211145A/xx unknown
- 1985-02-20 DE DE8585301122T patent/DE3573429D1/de not_active Expired
- 1985-02-20 EP EP85301122A patent/EP0155096B1/en not_active Expired
- 1985-02-20 DE DE8888119105T patent/DE3584172D1/de not_active Expired - Fee Related
- 1985-02-26 GR GR850483A patent/GR850483B/el not_active IP Right Cessation
- 1985-02-26 CA CA000475184A patent/CA1314541C/en not_active Expired - Lifetime
- 1985-02-26 DK DK085985A patent/DK166704B1/da not_active IP Right Cessation
- 1985-02-26 PT PT80010A patent/PT80010B/pt unknown
- 1985-02-26 IE IE47685A patent/IE58058B1/en not_active IP Right Cessation
- 1985-02-26 ES ES540705A patent/ES8702430A1/es not_active Expired
- 1985-02-26 AU AU39167/85A patent/AU584321B2/en not_active Expired
- 1985-02-26 IE IE922862A patent/IE922862L/xx unknown
- 1985-02-26 KR KR1019850001200A patent/KR900001206B1/ko not_active IP Right Cessation
-
1988
- 1988-06-01 JP JP63135348A patent/JPH0193600A/ja active Granted
-
1989
- 1989-04-18 AU AU33135/89A patent/AU626293B2/en not_active Expired
-
1990
- 1990-08-09 HK HK630/90A patent/HK63090A/xx not_active IP Right Cessation
-
1991
- 1991-02-06 AU AU70835/91A patent/AU7083591A/en not_active Abandoned
- 1991-03-22 CY CY1553A patent/CY1553A/xx unknown
-
1992
- 1992-10-30 AU AU27481/92A patent/AU651741B2/en not_active Ceased
-
1993
- 1993-02-09 NL NL930005C patent/NL930005I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
KR850006185A (ko) | 1985-10-02 |
ES8702430A1 (es) | 1987-01-01 |
KR900001206B1 (ko) | 1990-02-28 |
AU651741B2 (en) | 1994-07-28 |
NL930005I1 (nl) | 1993-04-01 |
DK85985A (da) | 1985-10-22 |
PT80010B (pt) | 1987-09-18 |
AU626293B2 (en) | 1992-07-30 |
GR850483B (pt) | 1985-06-26 |
EP0155096B1 (en) | 1989-10-04 |
AU7083591A (en) | 1991-07-11 |
AU3313589A (en) | 1989-08-10 |
EP0155096A3 (en) | 1986-07-02 |
IE58058B1 (en) | 1993-06-16 |
EP0155096A2 (en) | 1985-09-18 |
CY1553A (en) | 1991-03-22 |
HK63090A (en) | 1990-08-17 |
AU2748192A (en) | 1993-03-18 |
NZ211145A (en) | 1988-10-28 |
ES540705A0 (es) | 1987-01-01 |
JPH0193600A (ja) | 1989-04-12 |
DE3584172D1 (de) | 1991-10-24 |
IE922862L (en) | 1985-08-27 |
DK166704B1 (da) | 1993-06-28 |
AU3916785A (en) | 1985-09-05 |
DE3573429D1 (en) | 1989-11-09 |
JPH0541638B2 (pt) | 1993-06-24 |
IL74365A0 (en) | 1985-05-31 |
CA1314541C (en) | 1993-03-16 |
DK85985D0 (da) | 1985-02-26 |
PT80010A (en) | 1985-03-01 |
AU584321B2 (en) | 1989-05-25 |
NL930005I2 (nl) | 1993-09-16 |
IE850476L (en) | 1985-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL74365A (en) | 17beta-(n-t.-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one and pharmaceutical compositions containing it | |
IL74758A (en) | Acyltripeptides and pharmaceutical compositions containing them | |
NZ212005A (en) | Pyrrolobenzimidazoles and pharmaceutical compositions | |
GB2153678B (en) | Pharmaceutical composition | |
IL82221A0 (en) | Phenyl-piperazines and pharmaceutical compositions containing them | |
NZ212099A (en) | Substituted arylhydroxamates and pharmaceutical compositions | |
GB8413191D0 (en) | Pharmaceutical composition | |
IL77138A0 (en) | Pharmaceutical compositions containing 1-heteroaryl-4-arylpyrazolin-5-ones | |
IL79376A (en) | Substituted di-t-butylphenols and pharmaceutical compositions containing them | |
ZA859731B (en) | Pharmaceutical compositions containing tetrahydrobenzthiazoles | |
NZ214821A (en) | Spiro-dioxolanes, -dithiolanes and -oxothiolanes and pharmaceutical compositions | |
GB2153677B (en) | Pharmaceutical composition | |
IL75411A0 (en) | Dihydropyridines and pharmaceutical compositions containing them | |
NZ212953A (en) | 3-acyl-1-aminoalkyl-1h-indoles and pharmaceutical compositions thereof | |
NZ215070A (en) | Imidazole-indoles and pharmaceutical compositions | |
IL75427A0 (en) | Dihydropyridines and pharmaceutical compositions containing them | |
IL79003A0 (en) | Tetrahydroimidazoquinazolinones and pharmaceutical compositions containing them | |
NZ213581A (en) | Carboxyalkyldipeptides and pharmaceutical compositions | |
NZ216438A (en) | Steroid-pyrazoles and pharmaceutical compositions | |
PH19896A (en) | 4-phenyl-tetrahydro-furano-pyridine and pharmaceutical compositions containing them | |
IL74667A (en) | Spiro-oxazolidones,-thiazolidones and-imidazolidones and pharmaceutical compositions containing them | |
PH21779A (en) | Sulfonomidines and pharmaceutical compositions containing the same | |
PH23343A (en) | 8 0( acylaminoergolines and pharmaceutical compositions containing them | |
GB8410636D0 (en) | Pharmaceutical substances/compositions | |
IL79377A0 (en) | Substituted di-t-butylphenols and pharmaceutical compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXP | Patent expired |