IL73533A - Enzyme-resistant immunomodulatory peptides,and their preparation - Google Patents
Enzyme-resistant immunomodulatory peptides,and their preparationInfo
- Publication number
- IL73533A IL73533A IL73533A IL7353384A IL73533A IL 73533 A IL73533 A IL 73533A IL 73533 A IL73533 A IL 73533A IL 7353384 A IL7353384 A IL 7353384A IL 73533 A IL73533 A IL 73533A
- Authority
- IL
- Israel
- Prior art keywords
- enzyme
- resistant
- preparation
- immunomodulatory peptides
- peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/66—Thymopoietins
- C07K14/662—Thymopoietins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/66—Thymopoietins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/18—Thymus derived hormone or factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Vibration Dampers (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/553,281 US4505853A (en) | 1983-11-18 | 1983-11-18 | Enzyme-resistant immunomodulatory peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
IL73533A0 IL73533A0 (en) | 1985-02-28 |
IL73533A true IL73533A (en) | 1988-06-30 |
Family
ID=24208835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL73533A IL73533A (en) | 1983-11-18 | 1984-11-16 | Enzyme-resistant immunomodulatory peptides,and their preparation |
Country Status (14)
Country | Link |
---|---|
US (1) | US4505853A (de) |
EP (1) | EP0146266B1 (de) |
JP (2) | JPH0753752B2 (de) |
KR (1) | KR940001007B1 (de) |
AT (1) | ATE63748T1 (de) |
AU (1) | AU579595B2 (de) |
CA (1) | CA1269498A (de) |
DE (1) | DE3484616D1 (de) |
DK (1) | DK167928B1 (de) |
FI (1) | FI86860C (de) |
IL (1) | IL73533A (de) |
NO (1) | NO166943C (de) |
NZ (1) | NZ210194A (de) |
ZA (1) | ZA848973B (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3401545A1 (de) * | 1983-08-03 | 1985-02-14 | Hoechst Ag, 6230 Frankfurt | Neue peptide mit immunstimulierender wirkung, verfahren zu deren herstellung und deren verwendung |
US4629723A (en) * | 1984-06-27 | 1986-12-16 | Ortho Pharmaceutical Corporation | Potent thymopentin analogs |
AU602483B2 (en) * | 1985-01-18 | 1990-10-18 | Immunetech Pharmaceuticals | Immunoregulatory peptides |
DE3619633A1 (de) * | 1986-06-11 | 1987-12-17 | Hoechst Ag | Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung |
US5200506A (en) * | 1987-03-19 | 1993-04-06 | Eniricerche S.P.A. | Process for preparing new thymopentin retro-inverso analogs and fragments thereof and the intermediates obtained therein |
IT1216908B (it) * | 1987-03-19 | 1990-03-14 | Eniricerche Spa | Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche. |
US5656601A (en) * | 1987-06-19 | 1997-08-12 | Berlin-Chemie Ag | Acylated splenopentins, methods for their synthesis and their use |
JPH01125328A (ja) * | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
US5807830A (en) * | 1987-12-30 | 1998-09-15 | Cytoven J.V. | Method for treatment of purulent inflammatory diseases |
US5728680A (en) | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes |
GB8807427D0 (en) * | 1988-03-28 | 1988-05-05 | National Biological Standards Board | Peptides |
WO1989009229A1 (en) * | 1988-03-31 | 1989-10-05 | Immunobiology Research Institute, Inc. | Treatment of hiv viremic patients with thymopentin |
NZ229004A (en) * | 1988-05-19 | 1993-09-27 | Immunobiology Res Inst Inc | Tetrapeptides having t cell helper acitivity |
HU201095B (en) * | 1988-06-14 | 1990-09-28 | Richter Gedeon Vegyeszet | New peptides inhibiting the activity of the immune system and pharmaceutical compositions comprising same, as well as process for producing these peptides and compositions |
IT1226552B (it) * | 1988-07-29 | 1991-01-24 | Ellem Ind Farmaceutica | Peptidi immunostimolanti. |
US5225400A (en) * | 1988-07-29 | 1993-07-06 | Ellem Industria Farmaceutica S.R.L. | Immunostimulating peptides, a process for their preparation and pharmaceutical compositions containing them |
HU205143B (en) * | 1988-09-30 | 1992-03-30 | Immunobiology Res Inst Inc | Process for producing peptides having t cell suppressor activity and pharmaceutical compositions comprising same |
DE3833936C1 (de) * | 1988-10-05 | 1989-09-21 | Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De | |
US5811399A (en) * | 1988-12-14 | 1998-09-22 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants |
IT1227908B (it) * | 1988-12-23 | 1991-05-14 | Eniricerche S P A Milano Sclav | Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche |
US5218089A (en) * | 1988-12-23 | 1993-06-08 | Sclavo S.P.A. | Retro-inverso analogues of thymopentin and the method for their synthesis |
US5036050A (en) * | 1989-01-12 | 1991-07-30 | Immunobiology Research Institute, Inc. | Compositions containing thymopentin for topical treatment of skin disorders |
US5770576A (en) * | 1989-08-30 | 1998-06-23 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity |
JP2745351B2 (ja) * | 1991-02-14 | 1998-04-28 | 富士写真フイルム株式会社 | ペプチド誘導体及びその用途 |
DK53291D0 (da) * | 1991-03-25 | 1991-03-25 | Carlbiotech Ltd As | Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser |
EP0668770A1 (de) * | 1991-04-24 | 1995-08-30 | Warner-Lambert Company | Alpha-substituierte polypeptide und therapeutischer aktivität |
US5215964A (en) * | 1991-06-03 | 1993-06-01 | Immunobiology Research Institute, Inc. | Peptides useful in regulating the immune and nervous systems |
US6100380A (en) * | 1991-10-28 | 2000-08-08 | Cytran, Inc. | Immunomodulating peptides and methods of use |
US6066622A (en) * | 1991-10-28 | 2000-05-23 | Cytran, Inc. | Immunomodulating peptides and methods of use |
US5928896A (en) * | 1993-04-23 | 1999-07-27 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site |
US5965698A (en) * | 1993-04-23 | 1999-10-12 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site |
WO1994025482A1 (en) * | 1993-04-23 | 1994-11-10 | Evans Herbert J | Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site |
US5952465A (en) * | 1993-04-23 | 1999-09-14 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site |
US6258550B1 (en) | 1993-04-23 | 2001-07-10 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site |
US5639729A (en) * | 1993-08-26 | 1997-06-17 | Immunobiology Research Institute, Inc. | Tripeptides useful in immune and CNS therapy |
US6084066A (en) * | 1993-10-29 | 2000-07-04 | Virginia Commonwealth University | Polypetides that include conformation-constraining groups which flank a protein-protein interaction site |
US6849712B1 (en) * | 1998-01-22 | 2005-02-01 | Regents Of The University Of Minnesota | Peptides with β1 integrin subunit dependent cell adhesion modulating activity |
CN1927879B (zh) * | 2006-09-25 | 2010-11-24 | 吉林大学 | 胸腺五肽活性异构体及其在药物制备中的应用 |
CN101168560B (zh) * | 2006-10-23 | 2012-09-05 | 江苏正大天晴药业股份有限公司 | N-取代肽酰胺,其药物组合物与用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4077949A (en) | 1973-12-28 | 1978-03-07 | Sloan-Kettering Institute For Cancer Research | Polypeptide hormones of the thymus |
US4002740A (en) | 1975-08-21 | 1977-01-11 | Gideon Goldstein | Tridecapeptide compositions and methods |
US4190646A (en) * | 1975-11-11 | 1980-02-26 | Sloan-Kettering Institute For Cancer Research | Polypeptide compositions and methods |
US4261886A (en) * | 1980-03-13 | 1981-04-14 | Ortho Pharmaceutical Corporation | Peptides having thymopoietin-like activity |
CA1157466A (en) * | 1979-04-12 | 1983-11-22 | Gideon Goldstein | Peptides having thymopoietin-like activity |
JPS55149237A (en) * | 1979-04-12 | 1980-11-20 | Ortho Pharma Corp | Thymopoietin active peptide |
DE2938420A1 (de) | 1979-09-22 | 1981-04-09 | Hoechst Ag, 6000 Frankfurt | Neue peptide und verfahren zu ihrer herstellung |
US4309340A (en) * | 1980-03-31 | 1982-01-05 | American Home Products Corporation | Polypeptide compositions |
US4298523A (en) * | 1980-06-17 | 1981-11-03 | Ortho Pharmaceutical Corporation | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R |
US4369137A (en) * | 1980-06-17 | 1983-01-18 | Ortho Pharmaceutical Corporation | N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide |
US4361673A (en) | 1980-09-19 | 1982-11-30 | American Home Products Corporation | Polypeptide compositions |
US4305852A (en) * | 1980-10-20 | 1981-12-15 | American Home Products Corporation | Polypeptide compositions |
-
1983
- 1983-11-18 US US06/553,281 patent/US4505853A/en not_active Expired - Lifetime
-
1984
- 1984-11-12 NZ NZ210194A patent/NZ210194A/xx unknown
- 1984-11-14 CA CA000467773A patent/CA1269498A/en not_active Expired - Lifetime
- 1984-11-16 NO NO844579A patent/NO166943C/no not_active IP Right Cessation
- 1984-11-16 IL IL73533A patent/IL73533A/xx not_active IP Right Cessation
- 1984-11-16 DE DE8484307968T patent/DE3484616D1/de not_active Expired - Lifetime
- 1984-11-16 DK DK545584A patent/DK167928B1/da not_active IP Right Cessation
- 1984-11-16 FI FI844510A patent/FI86860C/fi not_active IP Right Cessation
- 1984-11-16 JP JP59242206A patent/JPH0753752B2/ja not_active Expired - Lifetime
- 1984-11-16 AT AT84307968T patent/ATE63748T1/de not_active IP Right Cessation
- 1984-11-16 EP EP84307968A patent/EP0146266B1/de not_active Expired - Lifetime
- 1984-11-16 ZA ZA848973A patent/ZA848973B/xx unknown
- 1984-11-17 KR KR1019840007210A patent/KR940001007B1/ko not_active IP Right Cessation
- 1984-11-19 AU AU35652/84A patent/AU579595B2/en not_active Ceased
-
1994
- 1994-09-22 JP JP6254375A patent/JP2633481B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA1269498A (en) | 1990-05-22 |
NZ210194A (en) | 1988-11-29 |
JPH07165791A (ja) | 1995-06-27 |
EP0146266A3 (en) | 1987-08-12 |
KR940001007B1 (ko) | 1994-02-08 |
FI86860C (fi) | 1992-10-26 |
JPS60123498A (ja) | 1985-07-02 |
JP2633481B2 (ja) | 1997-07-23 |
AU3565284A (en) | 1985-05-23 |
EP0146266A2 (de) | 1985-06-26 |
EP0146266B1 (de) | 1991-05-22 |
KR850004594A (ko) | 1985-07-25 |
AU579595B2 (en) | 1988-12-01 |
FI86860B (fi) | 1992-07-15 |
DE3484616D1 (de) | 1991-06-27 |
DK545584A (da) | 1985-05-19 |
FI844510L (fi) | 1985-05-19 |
DK545584D0 (da) | 1984-11-16 |
US4505853A (en) | 1985-03-19 |
ZA848973B (en) | 1986-06-25 |
FI844510A0 (fi) | 1984-11-16 |
ATE63748T1 (de) | 1991-06-15 |
NO166943C (no) | 1991-09-18 |
NO844579L (no) | 1985-05-20 |
DK167928B1 (da) | 1994-01-03 |
JPH0753752B2 (ja) | 1995-06-07 |
NO166943B (no) | 1991-06-10 |
IL73533A0 (en) | 1985-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
RH1 | Patent not in force |