IL72491A0 - Aminopyrimidinone derivatives,pharmaceutical compositions containing them,their use as histamine h2-antagonists,processes for their preparation and intermediates therefor - Google Patents
Aminopyrimidinone derivatives,pharmaceutical compositions containing them,their use as histamine h2-antagonists,processes for their preparation and intermediates thereforInfo
- Publication number
- IL72491A0 IL72491A0 IL72491A IL7249184A IL72491A0 IL 72491 A0 IL72491 A0 IL 72491A0 IL 72491 A IL72491 A IL 72491A IL 7249184 A IL7249184 A IL 7249184A IL 72491 A0 IL72491 A0 IL 72491A0
- Authority
- IL
- Israel
- Prior art keywords
- histamine
- antagonists
- processes
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838320505A GB8320505D0 (en) | 1983-07-29 | 1983-07-29 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL72491A0 true IL72491A0 (en) | 1984-11-30 |
Family
ID=10546495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72491A IL72491A0 (en) | 1983-07-29 | 1984-07-25 | Aminopyrimidinone derivatives,pharmaceutical compositions containing them,their use as histamine h2-antagonists,processes for their preparation and intermediates therefor |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0134096B1 (da) |
| JP (1) | JPS6051179A (da) |
| KR (1) | KR850001174A (da) |
| AT (1) | ATE40552T1 (da) |
| AU (1) | AU564650B2 (da) |
| CA (1) | CA1261831A (da) |
| CS (1) | CS244448B2 (da) |
| DD (1) | DD216933A5 (da) |
| DE (1) | DE3476541D1 (da) |
| DK (1) | DK368284A (da) |
| ES (1) | ES534620A0 (da) |
| FI (1) | FI842976A (da) |
| GB (1) | GB8320505D0 (da) |
| GR (1) | GR82226B (da) |
| HU (1) | HUT34743A (da) |
| IL (1) | IL72491A0 (da) |
| JO (1) | JO1327B1 (da) |
| NO (1) | NO843043L (da) |
| PT (1) | PT78977B (da) |
| ZA (1) | ZA845820B (da) |
| ZW (1) | ZW11584A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4772704A (en) * | 1983-09-21 | 1988-09-20 | Bristol-Myers Company | 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity |
| GB8421427D0 (en) * | 1984-08-23 | 1984-09-26 | Smith Kline French Lab | Chemical compounds |
| JP2007531753A (ja) | 2004-03-31 | 2007-11-08 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 非イミダゾール系複素環式化合物 |
| AU2007256931B2 (en) | 2006-05-30 | 2013-01-24 | Janssen Pharmaceutica N.V. | Substituted pyridyl amide compounds as modulators of the histamine H3 receptor |
| KR101546712B1 (ko) | 2007-11-20 | 2015-08-24 | 얀센 파마슈티카 엔.브이. | 히스타민 ｈ3 수용체의 조절제로서 사이클로알킬옥시- 및 헤테로사이클로알킬옥시피리딘 화합물 |
| WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN151188B (da) * | 1978-02-13 | 1983-03-05 | Smith Kline French Lab | |
| ZA793443B (en) * | 1978-07-26 | 1980-12-31 | Glaxo Group Ltd | Heterocyclic derivatives |
| US4496567A (en) * | 1978-11-13 | 1985-01-29 | Smith Kline & French Laboratories Limited | Phenyl alkylaminopyrimidones |
| US4521418A (en) * | 1979-02-21 | 1985-06-04 | Smith Kline & French Laboratories Limited | Guanidinothiazolyl derivatives |
| ZW21281A1 (en) * | 1980-10-01 | 1981-11-18 | Smith Kline French Lab | Amine derivatives |
| NZ202797A (en) * | 1981-12-28 | 1985-08-30 | Lilly Co Eli | Pyrimidine derivatives and pharmaceutical compositions |
-
1983
- 1983-07-29 GB GB838320505A patent/GB8320505D0/en active Pending
-
1984
- 1984-07-18 JO JO19841327A patent/JO1327B1/en active
- 1984-07-23 GR GR75407A patent/GR82226B/el unknown
- 1984-07-24 AU AU30991/84A patent/AU564650B2/en not_active Ceased
- 1984-07-24 CA CA000459505A patent/CA1261831A/en not_active Expired
- 1984-07-25 IL IL72491A patent/IL72491A0/xx unknown
- 1984-07-25 PT PT78977A patent/PT78977B/pt unknown
- 1984-07-25 AT AT84305045T patent/ATE40552T1/de not_active IP Right Cessation
- 1984-07-25 EP EP84305045A patent/EP0134096B1/en not_active Expired
- 1984-07-25 DE DE8484305045T patent/DE3476541D1/de not_active Expired
- 1984-07-26 ES ES534620A patent/ES534620A0/es active Granted
- 1984-07-26 FI FI842976A patent/FI842976A/fi not_active Application Discontinuation
- 1984-07-27 JP JP59158537A patent/JPS6051179A/ja active Pending
- 1984-07-27 ZW ZW115/84A patent/ZW11584A1/xx unknown
- 1984-07-27 ZA ZA845820A patent/ZA845820B/xx unknown
- 1984-07-27 DK DK368284A patent/DK368284A/da not_active Application Discontinuation
- 1984-07-27 DD DD84265728A patent/DD216933A5/de unknown
- 1984-07-27 CS CS845810A patent/CS244448B2/cs unknown
- 1984-07-27 KR KR1019840004474A patent/KR850001174A/ko not_active Application Discontinuation
- 1984-07-27 HU HU842902A patent/HUT34743A/hu unknown
- 1984-07-27 NO NO843043A patent/NO843043L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS581084A2 (en) | 1985-08-15 |
| FI842976A (fi) | 1985-01-30 |
| DE3476541D1 (de) | 1989-03-09 |
| ES8600254A1 (es) | 1985-09-16 |
| PT78977B (en) | 1986-06-05 |
| EP0134096B1 (en) | 1989-02-01 |
| GB8320505D0 (en) | 1983-09-01 |
| GR82226B (da) | 1984-12-13 |
| EP0134096A2 (en) | 1985-03-13 |
| FI842976A0 (fi) | 1984-07-26 |
| ES534620A0 (es) | 1985-09-16 |
| ZW11584A1 (en) | 1985-04-17 |
| KR850001174A (ko) | 1985-03-16 |
| ZA845820B (en) | 1985-06-26 |
| DK368284D0 (da) | 1984-07-27 |
| JO1327B1 (en) | 1986-11-30 |
| EP0134096A3 (en) | 1985-12-18 |
| AU564650B2 (en) | 1987-08-20 |
| HUT34743A (en) | 1985-04-28 |
| ATE40552T1 (de) | 1989-02-15 |
| CS244448B2 (en) | 1986-07-17 |
| AU3099184A (en) | 1985-01-31 |
| DD216933A5 (de) | 1985-01-02 |
| PT78977A (en) | 1984-08-01 |
| CA1261831A (en) | 1989-09-26 |
| NO843043L (no) | 1985-01-30 |
| DK368284A (da) | 1985-01-30 |
| JPS6051179A (ja) | 1985-03-22 |
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