IL72475A - 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them - Google Patents

1,4-dihydropyridine derivatives and pharmaceutical compositions containing them

Info

Publication number
IL72475A
IL72475A IL72475A IL7247584A IL72475A IL 72475 A IL72475 A IL 72475A IL 72475 A IL72475 A IL 72475A IL 7247584 A IL7247584 A IL 7247584A IL 72475 A IL72475 A IL 72475A
Authority
IL
Israel
Prior art keywords
sub
heterocyclic ring
dihydropyridine derivatives
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL72475A
Other languages
English (en)
Other versions
IL72475A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838319886A external-priority patent/GB8319886D0/en
Priority claimed from GB848400354A external-priority patent/GB8400354D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of IL72475A0 publication Critical patent/IL72475A0/xx
Publication of IL72475A publication Critical patent/IL72475A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Registering, Tensioning, Guiding Webs, And Rollers Therefor (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IL72475A 1983-07-23 1984-07-20 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them IL72475A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838319886A GB8319886D0 (en) 1983-07-23 1983-07-23 Therapeutic agents
GB848400354A GB8400354D0 (en) 1984-01-07 1984-01-07 Therapeutic agents

Publications (2)

Publication Number Publication Date
IL72475A0 IL72475A0 (en) 1984-11-30
IL72475A true IL72475A (en) 1987-10-20

Family

ID=26286678

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72475A IL72475A (en) 1983-07-23 1984-07-20 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4568677A (fr)
EP (1) EP0132375B1 (fr)
AT (1) ATE44146T1 (fr)
AU (1) AU547188B2 (fr)
CA (1) CA1265796A (fr)
CS (1) CS241549B2 (fr)
DD (1) DD226285A5 (fr)
DE (1) DE3478746D1 (fr)
DK (1) DK170069B1 (fr)
ES (1) ES8700856A1 (fr)
FI (1) FI79105C (fr)
GR (1) GR82230B (fr)
HU (1) HU212133B (fr)
IE (1) IE58443B1 (fr)
IL (1) IL72475A (fr)
NO (1) NO161174C (fr)
NZ (1) NZ208954A (fr)
PH (1) PH20479A (fr)
PL (1) PL142659B1 (fr)
PT (1) PT78958B (fr)
YU (1) YU43738B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8306666D0 (en) * 1983-03-10 1983-04-13 Pfizer Ltd Therapeutic agents
GR851819B (fr) * 1984-08-17 1985-11-26 Wyeth John & Brother Ltd
GB8501395D0 (en) * 1985-01-19 1985-02-20 Pfizer Ltd Dihydropyridine anti-ischaemic & anti-hypertensive agents
US4833150A (en) * 1985-03-14 1989-05-23 Nelson Research & Development Co. 1,4-dihydropyridines
JPS61227567A (ja) * 1985-04-01 1986-10-09 Eisai Co Ltd １，４−ジヒドロピリジン誘導体
HU199796B (en) * 1985-08-06 1990-03-28 Boehringer Biochemia Srl Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds
IT1201454B (it) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-diidropiridine-2-sostituite
GB8526411D0 (en) * 1985-10-25 1985-11-27 Pfizer Ltd Dihydropyridines
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents
EP0225175A3 (fr) * 1985-11-28 1988-12-28 FISONS plc Dérivés de dihydropyridine, leur procédé de préparation et les compositions pharmaceutiques les contenant
US4654372A (en) * 1986-01-10 1987-03-31 Warner-Lambert Company Method for using verapamil for treating stroke
US4849436A (en) * 1986-03-11 1989-07-18 Nelson Research & Development Co. 1,4-dihydropyridines
IT1197012B (it) * 1986-07-29 1988-11-25 Boehringer Biochemia Srl 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono
GB8710493D0 (en) * 1987-05-02 1987-06-03 Pfizer Ltd Dihydropyridines
WO2004033444A1 (fr) * 2002-10-07 2004-04-22 Artesian Therapeutics, Inc. Composes de dihydropyridine presentant a la fois la capacite de bloquer des canaux calciques de type l et la capacite d'inhiber l'activite de type 3 de la phosphodiesterase
US20070066619A1 (en) * 2002-10-07 2007-03-22 Artesian Therapeutics, Inc. Compounds having simultaneous ability to block L-type calcium channels and to inhibit phosphodiesterase type 3 activity
JP2008519850A (ja) * 2004-11-10 2008-06-12 シンタ ファーマシューティカルズ コーポレーション Ｉｌ−１２調節化合物
CN115557883A (zh) * 2022-10-28 2023-01-03 常州制药厂有限公司 一种氨氯地平的合成工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS228917B2 (en) * 1981-03-14 1984-05-14 Pfizer Method of preparing substituted derivatives of 1,4-dihydropyridine
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3363743D1 (en) * 1982-07-22 1986-07-03 Pfizer Ltd Dihydropyridine anti-ischaemic and antihypertensive agents
EP0107293A3 (fr) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
GB8414518D0 (en) * 1984-06-07 1984-07-11 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
HUT36113A (en) 1985-08-28
FI79105B (fi) 1989-07-31
CS557084A2 (en) 1985-07-16
HU212133B (en) 1996-05-28
YU130584A (en) 1986-12-31
US4568677A (en) 1986-02-04
AU3089984A (en) 1985-01-24
DE3478746D1 (en) 1989-07-27
FI79105C (fi) 1989-11-10
PH20479A (en) 1987-01-16
CS241549B2 (en) 1986-03-13
PL248857A1 (en) 1985-08-27
NO161174B (no) 1989-04-03
PL142659B1 (en) 1987-11-30
DK170069B1 (da) 1995-05-15
CA1265796A (fr) 1990-02-13
NZ208954A (en) 1986-11-12
NO842987L (no) 1985-01-24
ES534505A0 (es) 1986-11-16
PT78958B (en) 1986-10-21
PT78958A (en) 1984-08-01
DK355784D0 (da) 1984-07-20
YU43738B (en) 1989-10-31
FI842911A0 (fi) 1984-07-19
DD226285A5 (de) 1985-08-21
EP0132375B1 (fr) 1989-06-21
NO161174C (no) 1989-07-12
GR82230B (fr) 1984-12-13
IL72475A0 (en) 1984-11-30
ES8700856A1 (es) 1986-11-16
IE841905L (en) 1985-01-23
IE58443B1 (en) 1993-09-22
EP0132375A2 (fr) 1985-01-30
EP0132375A3 (en) 1987-07-01
FI842911A (fi) 1985-01-24
AU547188B2 (en) 1985-10-10
DK355784A (da) 1985-01-24
ATE44146T1 (de) 1989-07-15

Similar Documents

Publication Publication Date Title
IL72475A0 (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them
DE3363743D1 (en) Dihydropyridine anti-ischaemic and antihypertensive agents
IL70477A (en) Dihydropyridines and pharmaceutical compositions containing them
IL75165A0 (en) Dihydropyridines and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees