IL71187A0 - 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them - Google Patents

1,4-dihydropyridine derivatives and pharmaceutical compositions containing them

Info

Publication number
IL71187A0
IL71187A0 IL71187A IL7118784A IL71187A0 IL 71187 A0 IL71187 A0 IL 71187A0 IL 71187 A IL71187 A IL 71187A IL 7118784 A IL7118784 A IL 7118784A IL 71187 A0 IL71187 A0 IL 71187A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
dihydropyridine derivatives
dihydropyridine
derivatives
Prior art date
Application number
IL71187A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL71187A0 publication Critical patent/IL71187A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL71187A 1983-03-10 1984-03-08 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them IL71187A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838306666A GB8306666D0 (en) 1983-03-10 1983-03-10 Therapeutic agents

Publications (1)

Publication Number Publication Date
IL71187A0 true IL71187A0 (en) 1984-06-29

Family

ID=10539350

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71187A IL71187A0 (en) 1983-03-10 1984-03-08 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4590195A (fr)
EP (1) EP0119050B1 (fr)
JP (1) JPS59175466A (fr)
KR (1) KR840008147A (fr)
AU (1) AU546634B2 (fr)
DE (1) DE3477379D1 (fr)
DK (1) DK168378B1 (fr)
ES (3) ES8506275A1 (fr)
FI (1) FI840955A (fr)
GB (1) GB8306666D0 (fr)
GR (1) GR81872B (fr)
HU (1) HU191220B (fr)
IE (1) IE57116B1 (fr)
IL (1) IL71187A0 (fr)
PH (1) PH20692A (fr)
PL (2) PL252773A1 (fr)
PT (1) PT78219B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8421039D0 (en) * 1984-08-17 1984-09-19 Wyeth John & Brother Ltd Heterocyclic compounds
GB8501395D0 (en) * 1985-01-19 1985-02-20 Pfizer Ltd Dihydropyridine anti-ischaemic & anti-hypertensive agents
IT1204421B (it) * 1986-06-27 1989-03-01 Boehringer Biochemia Srl 2-(aminoalchiltio)metil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono
WO1987000836A1 (fr) * 1985-08-06 1987-02-12 Boehringer Biochemia Robin S.P.A. 1,4-dihydropyridines pharmaceutiquement actives a substitution 2-thiomethyle
IT1201454B (it) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-diidropiridine-2-sostituite
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents
EP0225175A3 (fr) * 1985-11-28 1988-12-28 FISONS plc Dérivés de dihydropyridine, leur procédé de préparation et les compositions pharmaceutiques les contenant
DE3621104A1 (de) * 1986-06-24 1988-01-07 Heumann Pharma Gmbh & Co 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1197012B (it) * 1986-07-29 1988-11-25 Boehringer Biochemia Srl 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono
FR2602231B1 (fr) * 1986-08-04 1988-10-28 Adir Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
IT1213555B (it) * 1986-12-11 1989-12-20 Boehringer Biochemia Srl 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono.
IT1215381B (it) * 1987-03-12 1990-02-08 Boehringer Biochemia Srl Farmaceutiche che le contengono. carbonil- e solfonil- derivati di 2-(aminoalchiltio)metil-1,4-diidropiridine, un metodo per la loro preparazione e composizioni
GB8710493D0 (en) * 1987-05-02 1987-06-03 Pfizer Ltd Dihydropyridines
NZ229828A (en) * 1988-08-09 1992-03-26 Squibb & Sons Inc Aryl cyanoguanidine derivatives and pharmaceutical compositions
US5278169A (en) * 1988-08-09 1994-01-11 E. R. Squibb & Sons, Inc. Method of treating or prevention of fibrillation of the heart
IE71183B1 (en) * 1988-12-27 1997-01-29 Takeda Chemical Industries Ltd Guanidine derivatives their production and insecticides
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
WO2003089414A1 (fr) * 2002-04-13 2003-10-30 Hanlim Pharmaceutical Co., Ltd. Nicotinate d'amlodipine et son procede de preparation
US20070066619A1 (en) * 2002-10-07 2007-03-22 Artesian Therapeutics, Inc. Compounds having simultaneous ability to block L-type calcium channels and to inhibit phosphodiesterase type 3 activity
EP1554267A1 (fr) * 2002-10-07 2005-07-20 Artesian Therapeutics, Inc. Composes de dihydropyridine presentant a la fois la capacite de bloquer des canaux calciques de type l et la capacite d'inhiber l'activite de type 3 de la phosphodiesterase

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974278A (en) * 1973-07-12 1976-08-10 Bayer Aktiengesellschaft 1,4-Dihydropyridine esters
US4177278A (en) * 1977-04-05 1979-12-04 Bayer Aktiengesellschaft 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use
JPS5547656A (en) * 1978-09-29 1980-04-04 Dainippon Pharmaceut Co Ltd 2-(2-substituted aminoethyl)-1,4-dihydropyridine derivative and its derivative
SE7910521L (sv) * 1979-12-20 1981-06-21 Haessle Ab Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
CS228917B2 (en) * 1981-03-14 1984-05-14 Pfizer Method of preparing substituted derivatives of 1,4-dihydropyridine
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
US4568677A (en) * 1983-07-23 1986-02-04 Pfizer Inc. 2-(4-Pyrimidone alkoxyalkyl) dihydropyridine anti-ischaemic and antihypertensive agents

Also Published As

Publication number Publication date
ES530379A0 (es) 1985-07-01
DK135884D0 (da) 1984-02-29
EP0119050A2 (fr) 1984-09-19
ES8507111A1 (es) 1985-08-16
KR840008147A (ko) 1984-12-13
AU2546484A (en) 1984-09-13
IE57116B1 (en) 1992-05-06
FI840955A (fi) 1984-09-11
EP0119050A3 (en) 1987-07-01
PH20692A (en) 1987-03-24
PT78219B (en) 1986-08-12
GR81872B (fr) 1984-12-12
DK168378B1 (da) 1994-03-21
AU546634B2 (en) 1985-09-12
PL246574A1 (en) 1985-08-13
HU191220B (en) 1987-01-28
ES537268A0 (es) 1985-08-16
JPS59175466A (ja) 1984-10-04
DE3477379D1 (en) 1989-04-27
IE840585L (en) 1984-09-10
PL252773A1 (en) 1985-11-19
PT78219A (en) 1984-04-01
ES8507112A1 (es) 1985-08-16
EP0119050B1 (fr) 1989-03-22
ES8506275A1 (es) 1985-07-01
GB8306666D0 (en) 1983-04-13
ES537269A0 (es) 1985-08-16
FI840955A0 (fi) 1984-03-08
US4590195A (en) 1986-05-20
DK135884A (da) 1984-09-11

Similar Documents

Publication Publication Date Title
NZ212895A (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions
DE3265978D1 (en) 1,4-dihydropyridine derivative and pharmaceutical composition containing same
IL72028A0 (en) Aminomethyl-oxooxazolidinylbenzene derivatives and pharmaceutical compositions containing them
IL73706A0 (en) 2,2'-iminobisethanol derivatives,their preparation and pharmaceutical compositions containing them
IL76405A (en) 1,3-diacyl-2-oxindole derivatives and pharmaceutical compositions containing them
IL72566A (en) Androst-5-en-17-one and 5alpha-androstan-17-one derivatives and pharmaceutical compositions containing the same
IL71187A0 (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them
IL70756A (en) 3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL73332A (en) 5-amino-6-phenyl-2,3-dihydro-3-imino-1,2,4-triazine derivatives,their preparation and pharmaceutical compositions containing them
NZ209064A (en) N 6 -diarylalkyl-adenosine derivatives and pharmaceutical compositions
IL75943A (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL71631A0 (en) Dihydropyridines,their preparation and pharmaceutical compositions containing them
IL83413A0 (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL70755A (en) 3-amino-4-cyano-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL72562A (en) 6,7-dimethoxy-4-piperidino-quinazoline derivatives and pharmaceutical compositions containing them
IL72152A0 (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
ZA86301B (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
NZ210223A (en) Substituted 3-carbamoyl-1,4-dihydropyridine derivatives and pharmaceutical compositions
DE3473444D1 (en) Acylindole derivatives and pharmaceutical compositions containing them
IL72239A (en) 1,5-diphenylpent-1-en-4-yne derivatives,and anticancer pharmaceutical compositions containing them
IL73278A0 (en) Pharmaceutical compositions containing 1,2-dithiolan derivatives,certain such derivatives and their preparation
IL74071A0 (en) Dihydropyridine derivatives and pharmaceutical compositions containing them
PH19575A (en) Cephalosporing derivatives and pharmaceutical compositions thereof
IL73224A (en) 2-dioxacycloalkylthiopenem derivatives and pharmaceutical compositions containing them
EP0184841A3 (en) 1,4-dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing same