IL70776A - Recombinant dna molecule encoding at least one polypeptide displaying the immunogenicity of at least one merozoite antigen or asexual blood stage antigen of p.falciparum,vectors comprising the dna molecule,host cells transformed thereby,immunogenic polypeptides produced by host cells and compositions containing the polypeptides - Google Patents
Recombinant dna molecule encoding at least one polypeptide displaying the immunogenicity of at least one merozoite antigen or asexual blood stage antigen of p.falciparum,vectors comprising the dna molecule,host cells transformed thereby,immunogenic polypeptides produced by host cells and compositions containing the polypeptidesInfo
- Publication number
- IL70776A IL70776A IL70776A IL7077684A IL70776A IL 70776 A IL70776 A IL 70776A IL 70776 A IL70776 A IL 70776A IL 7077684 A IL7077684 A IL 7077684A IL 70776 A IL70776 A IL 70776A
- Authority
- IL
- Israel
- Prior art keywords
- host cells
- dna molecule
- antigen
- polypeptides
- falciparum
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 3
- 102000053602 DNA Human genes 0.000 title 2
- 239000000427 antigen Substances 0.000 title 2
- 102000036639 antigens Human genes 0.000 title 2
- 108091007433 antigens Proteins 0.000 title 2
- 210000004027 cell Anatomy 0.000 title 2
- 108020004414 DNA Proteins 0.000 title 1
- 241000223960 Plasmodium falciparum Species 0.000 title 1
- 206010035500 Plasmodium falciparum infection Diseases 0.000 title 1
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 230000005847 immunogenicity Effects 0.000 title 1
- 210000003936 merozoite Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPF784383 | 1983-01-28 | ||
AUPF978883 | 1983-06-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL70776A0 IL70776A0 (en) | 1984-04-30 |
IL70776A true IL70776A (en) | 1991-09-16 |
Family
ID=25642630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL70776A IL70776A (en) | 1983-01-28 | 1984-01-25 | Recombinant dna molecule encoding at least one polypeptide displaying the immunogenicity of at least one merozoite antigen or asexual blood stage antigen of p.falciparum,vectors comprising the dna molecule,host cells transformed thereby,immunogenic polypeptides produced by host cells and compositions containing the polypeptides |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0134799B1 (no) |
JP (1) | JPH06225786A (no) |
AU (1) | AU569722B2 (no) |
DE (1) | DE3486110D1 (no) |
DK (1) | DK467484A (no) |
ES (1) | ES8606494A1 (no) |
GB (1) | GB2143830B (no) |
GR (1) | GR81750B (no) |
IL (1) | IL70776A (no) |
MY (1) | MY102594A (no) |
NO (1) | NO843872L (no) |
OA (1) | OA07823A (no) |
PT (1) | PT78032B (no) |
SG (1) | SG41089G (no) |
WO (1) | WO1984002917A1 (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2145092B (en) * | 1983-01-28 | 1988-04-07 | Univ New York | Protective peptide antigen |
EP0135108A3 (en) * | 1983-08-12 | 1988-07-13 | Rockefeller University | Nucleotide hybridization assay for protozoan parasites |
WO1985003724A1 (en) * | 1984-02-21 | 1985-08-29 | National Research Development Corporation | Improvements in or relating to the production of malaria vaccines |
EP0154454B1 (en) * | 1984-02-22 | 1991-07-03 | The Wellcome Foundation Limited | Cloning of dna for protozoal antigens |
US5126264A (en) * | 1984-09-11 | 1992-06-30 | The Walter & Eliza Hall Institute Of Medical Research | The RESA and FIRA antigens of plasmodium falciparum |
IL76338A (en) * | 1984-09-11 | 1994-08-26 | Saramane Pty Ltd | Plasmodium plasmodium immunogenic polypeptides, AND molecules encoding them, a method for preparing the polypeptides and preparations containing the polypeptide |
NZ215023A (en) * | 1985-02-07 | 1989-07-27 | Smithkline Beckman Corp | Vaccine against plasmodium falciparum and antigenic peptides |
CN86100979A (zh) * | 1985-02-07 | 1986-12-17 | 史密丝克莱恩贝克曼公司 | 疟疾疫苗的制备方法 |
JPS62502933A (ja) * | 1985-02-20 | 1987-11-26 | メモリアル スロ−ン−ケツタリング キヤンサ− センタ− | 分子量130,000ダルトンと155,000ダルトンを持つプラスモディウム・ファルシパルムのグリコホリン結合蛋白に対するcDNAのコ−ド付け |
EP0217877A4 (en) * | 1985-04-11 | 1988-03-30 | Inst Medical W & E Hall | VERY REPEATABLE ANTIGENS FROM PLASMODIUM FALCIPARUM. |
IL79880A0 (en) * | 1985-08-29 | 1986-11-30 | Inst Medical W & E Hall | Recombinant virus |
JPS63502002A (ja) * | 1985-12-24 | 1988-08-11 | ザ・ワルタ−・アンド・エリザ・ホ−ル・インスティテュ−ト・オヴ・メディカル・リサ−チ | 無性の血中段階におけるプラズモジウム・ファルシパルムの抗原 |
KR880701243A (ko) * | 1986-03-14 | 1988-07-26 | 원본미기재 | 말라리아에 대한 보호 면역을 제공하는 폴리펩티드 |
US5006514A (en) * | 1986-03-20 | 1991-04-09 | Sawai Pharmaceutical Co., Ltd. | α,α-trehalose trimycolates and pharmaceutical compositions |
FR2610631B1 (fr) * | 1987-02-09 | 1989-11-24 | Pasteur Institut | Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme |
FR2672290B1 (fr) | 1991-02-05 | 1995-04-21 | Pasteur Institut | Sequences peptidiques specifiques des stades hepatiques de p. falciparum porteuses d'epitopes capables de stimuler les lymphocytes t. |
DE3741057A1 (de) * | 1987-03-18 | 1988-09-29 | Behringwerke Ag | Klonierung von malaria-spezifischen dna-sequenzen:isolierung des gens fuer das 140 kd protein |
ZA888983B (en) * | 1987-12-01 | 1989-08-30 | Saramane Pty Ltd | Rhoptry antigen of plasmodium falciparum |
DE68922896T2 (de) * | 1988-02-12 | 1995-11-16 | Saramane Pty Ltd | RHOPTRY-MEMBRAN-ANTIGEN VON -i(PLASMODIUM FALCIPARUM). |
GB8819209D0 (en) * | 1988-08-12 | 1988-09-14 | Research Corp Ltd | Polypeptide & dna encoding same |
US5231168A (en) * | 1988-09-16 | 1993-07-27 | Statens Seruminstitut | Malaria antigen |
GB8905857D0 (en) * | 1989-03-14 | 1989-04-26 | Hoffmann La Roche | Plasmodium merozoite rhoptries antigen |
CA2011031C (en) * | 1989-03-14 | 2000-07-18 | Robert George Ridley | Plasmodium merozoite rhoptries antigen and derivatives thereof |
GB9002512D0 (en) * | 1990-02-05 | 1990-04-04 | 3I Res Expl Ltd | Polypeptides and dna encoding same |
KR20020028385A (ko) * | 2000-10-09 | 2002-04-17 | 박제철 | 마커를 이용한 말라리아 원충에 감염된 모기 검출방법 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5434837B2 (no) * | 1972-02-08 | 1979-10-29 | ||
DE3033776A1 (de) * | 1980-09-09 | 1982-04-22 | Behringwerke Ag, 3550 Marburg | Verfahren zur vermehrung von protozoen |
FI64813C (fi) * | 1980-12-31 | 1984-01-10 | Ilkka Antero Palva | Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer |
GB2145092B (en) * | 1983-01-28 | 1988-04-07 | Univ New York | Protective peptide antigen |
JPS57156421A (en) * | 1981-03-24 | 1982-09-27 | Nippon Koutai Kenkyusho:Kk | Malaria vaccine and its preparation |
JPS5810524A (ja) * | 1981-04-15 | 1983-01-21 | ザ・ウエルカム・フアウンデ−シヨン・リミテツド | 保護誘発、蛋白性抗原 |
IL65496A (en) * | 1981-04-15 | 1985-10-31 | Wellcome Found | Protozoal antigen,its preparation and vaccine containing it |
EP0071705B1 (en) * | 1981-05-21 | 1989-11-23 | The Wellcome Foundation Limited | Protozoal antigen |
GB2099300B (en) * | 1981-05-21 | 1985-02-27 | Wellcome Found | Antigens from parasites of the genus plasmodium |
WO1983002896A1 (en) * | 1982-02-17 | 1983-09-01 | D'antonio, Lawrence, E. | Method for the purification of parasite antigenic factors |
DE3221881A1 (de) * | 1982-06-09 | 1983-12-15 | Münchener Apparatebau Kimmel GmbH, 8012 Ottobrunn | Verfahren zur herstellung eines impfstoffs gegen parasitaere krankheitserreger |
-
1983
- 1983-01-28 AU AU23842/84A patent/AU569722B2/en not_active Ceased
-
1984
- 1984-01-25 IL IL70776A patent/IL70776A/xx not_active IP Right Cessation
- 1984-01-26 GR GR73633A patent/GR81750B/el unknown
- 1984-01-27 DE DE8484900598T patent/DE3486110D1/de not_active Expired - Fee Related
- 1984-01-27 PT PT78032A patent/PT78032B/pt unknown
- 1984-01-27 EP EP84900598A patent/EP0134799B1/en not_active Expired - Lifetime
- 1984-01-27 GB GB08424104A patent/GB2143830B/en not_active Expired
- 1984-01-27 ES ES529232A patent/ES8606494A1/es not_active Expired
- 1984-01-27 WO PCT/AU1984/000016 patent/WO1984002917A1/en active IP Right Grant
- 1984-09-25 OA OA58399A patent/OA07823A/xx unknown
- 1984-09-27 NO NO843872A patent/NO843872L/no unknown
- 1984-09-28 DK DK467484A patent/DK467484A/da not_active Application Discontinuation
-
1987
- 1987-09-11 MY MYPI87001636A patent/MY102594A/en unknown
-
1989
- 1989-07-07 SG SG410/89A patent/SG41089G/en unknown
-
1993
- 1993-10-27 JP JP5268818A patent/JPH06225786A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE3486110D1 (de) | 1993-04-29 |
JPH06225786A (ja) | 1994-08-16 |
EP0134799B1 (en) | 1993-03-24 |
IL70776A0 (en) | 1984-04-30 |
ES8606494A1 (es) | 1986-04-16 |
GB2143830A (en) | 1985-02-20 |
PT78032B (en) | 1986-03-27 |
EP0134799A4 (en) | 1985-07-30 |
GB2143830B (en) | 1987-02-25 |
DK467484D0 (da) | 1984-09-28 |
WO1984002917A1 (en) | 1984-08-02 |
DK467484A (da) | 1984-09-28 |
ES529232A0 (es) | 1986-04-16 |
AU569722B2 (en) | 1988-02-18 |
EP0134799A1 (en) | 1985-03-27 |
PT78032A (en) | 1984-02-01 |
GB8424104D0 (en) | 1984-10-31 |
OA07823A (en) | 1986-11-20 |
AU2384284A (en) | 1984-08-09 |
GR81750B (no) | 1984-12-12 |
SG41089G (en) | 1989-12-22 |
MY102594A (en) | 1992-08-17 |
DE3486110T2 (no) | 1993-09-09 |
NO843872L (no) | 1984-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |