IL70740A - 3-amino-6-aryl-pyridazines and 2-amino-4-aryl pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

3-amino-6-aryl-pyridazines and 2-amino-4-aryl pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL70740A
IL70740A IL70740A IL7074084A IL70740A IL 70740 A IL70740 A IL 70740A IL 70740 A IL70740 A IL 70740A IL 7074084 A IL7074084 A IL 7074084A IL 70740 A IL70740 A IL 70740A
Authority
IL
Israel
Prior art keywords
amino
aryl
pyridazines
preparation
image
Prior art date
Application number
IL70740A
Other languages
English (en)
Other versions
IL70740A0 (en
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of IL70740A0 publication Critical patent/IL70740A0/xx
Publication of IL70740A publication Critical patent/IL70740A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Polymerisation Methods In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL70740A 1983-01-21 1984-01-20 3-amino-6-aryl-pyridazines and 2-amino-4-aryl pyrimidines,their preparation and pharmaceutical compositions containing them IL70740A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8300954A FR2539741A1 (fr) 1983-01-21 1983-01-21 Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent

Publications (2)

Publication Number Publication Date
IL70740A0 IL70740A0 (en) 1984-04-30
IL70740A true IL70740A (en) 1986-09-30

Family

ID=9285183

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70740A IL70740A (en) 1983-01-21 1984-01-20 3-amino-6-aryl-pyridazines and 2-amino-4-aryl pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (30)

Country Link
US (1) US4624952A (hu)
EP (1) EP0114770B1 (hu)
JP (1) JPS59137469A (hu)
KR (1) KR910000640B1 (hu)
AT (1) ATE28453T1 (hu)
AU (1) AU563160B2 (hu)
CA (1) CA1217490A (hu)
CS (1) CS242894B2 (hu)
DD (1) DD216014A5 (hu)
DE (1) DE3464909D1 (hu)
DK (1) DK25684A (hu)
EG (1) EG16212A (hu)
ES (1) ES8407040A1 (hu)
FI (1) FI79537C (hu)
FR (1) FR2539741A1 (hu)
GR (1) GR79766B (hu)
HU (1) HU191586B (hu)
IE (1) IE56569B1 (hu)
IL (1) IL70740A (hu)
MA (1) MA20007A1 (hu)
NO (1) NO159170C (hu)
NZ (1) NZ206906A (hu)
OA (1) OA07638A (hu)
PH (1) PH21060A (hu)
PL (1) PL143224B1 (hu)
PT (1) PT77966B (hu)
SG (1) SG2189G (hu)
SU (1) SU1342415A3 (hu)
YU (1) YU10384A (hu)
ZA (1) ZA84342B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
FR2567518B1 (fr) * 1984-07-11 1987-11-13 Sanofi Sa Nouveaux composes a noyau heterocyclique azote, leur preparation et les medicaments qui en contiennent
DE3517617A1 (de) * 1985-05-15 1986-11-20 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Neue pyridaziniumverbindungen, verfahren zu deren herstellung und diese enthaltende fungizide und algizide mittel
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.
US5631255A (en) * 1989-02-07 1997-05-20 Sanofi Pyridazine derivatives
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US5952331A (en) * 1996-05-23 1999-09-14 Syntex (Usa) Inc. Aryl pyrimidine derivatives
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
WO2008096746A1 (ja) * 2007-02-06 2008-08-14 Takeda Pharmaceutical Company Limited スピロ化合物およびその用途
CN107614503B (zh) * 2015-04-29 2020-03-10 广东众生药业股份有限公司 稠环或三环芳基嘧啶化合物用作激酶抑制剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
US4302455A (en) * 1980-04-14 1981-11-24 Merck & Co., Inc. 2-(4-Aminopiperidino)pyrazines
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2511366A1 (fr) * 1981-08-11 1983-02-18 Sanofi Sa Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent

Also Published As

Publication number Publication date
FI79537C (fi) 1990-01-10
FI79537B (fi) 1989-09-29
YU10384A (en) 1986-10-31
PT77966A (fr) 1984-02-01
SU1342415A3 (ru) 1987-09-30
ZA84342B (en) 1984-08-29
GR79766B (hu) 1984-10-31
EG16212A (en) 1989-06-30
NO159170B (no) 1988-08-29
ES528921A0 (es) 1984-09-01
NO840214L (no) 1984-07-23
DD216014A5 (de) 1984-11-28
KR910000640B1 (ko) 1991-01-31
EP0114770B1 (en) 1987-07-22
DK25684A (da) 1984-07-22
MA20007A1 (fr) 1984-10-01
FR2539741B1 (hu) 1985-05-17
DE3464909D1 (en) 1987-08-27
EP0114770A2 (fr) 1984-08-01
ATE28453T1 (de) 1987-08-15
AU2323684A (en) 1984-07-26
AU563160B2 (en) 1987-07-02
PT77966B (fr) 1986-07-11
IE56569B1 (en) 1991-09-11
IE840102L (en) 1984-07-21
FR2539741A1 (fr) 1984-07-27
DK25684D0 (da) 1984-01-20
CA1217490A (en) 1987-02-03
OA07638A (fr) 1985-05-23
PL143224B1 (en) 1988-01-30
NO159170C (no) 1988-12-07
EP0114770A3 (en) 1984-08-22
SG2189G (en) 1989-06-02
ES8407040A1 (es) 1984-09-01
PH21060A (en) 1987-07-10
US4624952A (en) 1986-11-25
FI840238A (fi) 1984-07-22
NZ206906A (en) 1987-05-29
CS42484A2 (en) 1985-08-15
IL70740A0 (en) 1984-04-30
CS242894B2 (en) 1986-05-15
PL245836A1 (en) 1985-07-02
FI840238A0 (fi) 1984-01-20
HU191586B (en) 1987-03-30
JPS59137469A (ja) 1984-08-07
KR840007406A (ko) 1984-12-07

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