IL69593A - Pilocarpine prodrugs,their preparation and pharmaceutical compositions containing them - Google Patents
Pilocarpine prodrugs,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL69593A IL69593A IL69593A IL6959383A IL69593A IL 69593 A IL69593 A IL 69593A IL 69593 A IL69593 A IL 69593A IL 6959383 A IL6959383 A IL 6959383A IL 69593 A IL69593 A IL 69593A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- pilocarpine
- prodrugs
- Prior art date
Links
- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical compound C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 title 1
- QCHFTSOMWOSFHM-UHFFFAOYSA-N SJ000285536 Natural products C1OC(=O)C(CC)C1CC1=CN=CN1C QCHFTSOMWOSFHM-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229960001416 pilocarpine Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK417082 | 1982-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL69593A true IL69593A (en) | 1988-09-30 |
Family
ID=8130941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69593A IL69593A (en) | 1982-09-17 | 1983-08-29 | Pilocarpine prodrugs,their preparation and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4742073A (pt) |
| EP (1) | EP0106541A3 (pt) |
| JP (1) | JPS59130275A (pt) |
| KR (1) | KR840006213A (pt) |
| AU (1) | AU557083B2 (pt) |
| CA (1) | CA1235416A (pt) |
| ES (1) | ES8502977A1 (pt) |
| IL (1) | IL69593A (pt) |
| NZ (1) | NZ205617A (pt) |
| PT (1) | PT77347B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU557083B2 (en) * | 1982-09-17 | 1986-12-04 | Hans Bundgaard | Pilocarpine prodrugs |
| DK406686D0 (da) * | 1986-08-26 | 1986-08-26 | Hans Bundgaard | Carboxylsyrederivater |
| US5066663A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Company | Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors |
| US5066665A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Co. | Substituted isoxazolidin-3-ones and derivatives thereof acting at muscarinic receptors |
| FI98910C (fi) | 1992-05-29 | 1997-09-10 | Santen Oy | Menetelmä farmaseuttisesti käyttökelpoisten pilokarpiinijohdannaisten valmistamiseksi |
| US5436350A (en) * | 1990-11-30 | 1995-07-25 | Jaervinen; Tomi | Bispilocarpic acid ester derivatives and process for their preparation |
| FI98815C (fi) | 1990-11-30 | 1997-08-25 | Santen Oy | Menetelmä uusien, farmakologisesti käyttökelpoisten bispilokarpiinihapon esterijohdannaisten valmistamiseksi |
| WO1993024466A1 (en) * | 1992-05-29 | 1993-12-09 | Leiras Oy | Novel pilocarpine derivatives and process for their preparation |
| US5521210A (en) * | 1993-04-13 | 1996-05-28 | Allergan, Inc. | Ophthalmic use of muscarinic agonists having increased duration of activity |
| CN115536641B (zh) * | 2022-09-29 | 2024-12-27 | 广州润尔眼科生物科技有限公司 | 一种内酯化合物及其制备方法与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3470197A (en) * | 1967-08-30 | 1969-09-30 | Miles Lab | 1-substituted derivatives of 3-ethyl-4 - (1-methylimidazolyl-(5)-methyl)-2-pyrrolidinone |
| US3631059A (en) * | 1967-09-11 | 1971-12-28 | John T Goorley | Process for the extraction and purification of pilocarpine |
| US4045558A (en) * | 1975-10-08 | 1977-08-30 | Merck & Co., Inc. | Pilocarpine salts |
| US4061722A (en) * | 1976-04-26 | 1977-12-06 | Interx Research Corporation | Selected quaternary ammonium salts of pilocarpine useful in reducing intraocular pressure in warm-blooded animals |
| AU557083B2 (en) * | 1982-09-17 | 1986-12-04 | Hans Bundgaard | Pilocarpine prodrugs |
-
1983
- 1983-08-29 AU AU18494/83A patent/AU557083B2/en not_active Ceased
- 1983-08-29 IL IL69593A patent/IL69593A/xx unknown
- 1983-09-16 NZ NZ205617A patent/NZ205617A/en unknown
- 1983-09-16 CA CA000436880A patent/CA1235416A/en not_active Expired
- 1983-09-16 ES ES525656A patent/ES8502977A1/es not_active Expired
- 1983-09-16 EP EP83305437A patent/EP0106541A3/en not_active Withdrawn
- 1983-09-16 JP JP58172052A patent/JPS59130275A/ja active Pending
- 1983-09-16 US US06/533,646 patent/US4742073A/en not_active Expired - Fee Related
- 1983-09-16 PT PT77347A patent/PT77347B/pt not_active IP Right Cessation
- 1983-09-17 KR KR1019830004369A patent/KR840006213A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU1849483A (en) | 1984-03-22 |
| EP0106541A3 (en) | 1985-12-18 |
| NZ205617A (en) | 1986-06-11 |
| AU557083B2 (en) | 1986-12-04 |
| KR840006213A (ko) | 1984-11-22 |
| EP0106541A2 (en) | 1984-04-25 |
| JPS59130275A (ja) | 1984-07-26 |
| CA1235416A (en) | 1988-04-19 |
| PT77347A (en) | 1983-10-01 |
| US4742073A (en) | 1988-05-03 |
| ES525656A0 (es) | 1985-02-01 |
| PT77347B (en) | 1986-03-11 |
| ES8502977A1 (es) | 1985-02-01 |
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