IL68142A0 - Preparation of diphenyl ethers - Google Patents
Preparation of diphenyl ethersInfo
- Publication number
- IL68142A0 IL68142A0 IL68142A IL6814283A IL68142A0 IL 68142 A0 IL68142 A0 IL 68142A0 IL 68142 A IL68142 A IL 68142A IL 6814283 A IL6814283 A IL 6814283A IL 68142 A0 IL68142 A0 IL 68142A0
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- formula
- hereinbefore defined
- see diagramm
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
Abstract
1. Process for the preparation of compounds of formula (I) see diagramm : EP0089517,P19,F2 wherein n represents an integer from 1 to 3, if R1 represents hydrogen, halogen or alkyl with 1 to 8 carbon atoms or n represents 1 if R1 represents hydrogen, trifluoromethyl, alkoxy with 1 to 8 carbon atoms or acetyl, R2 represents hydrogen ; alkyl, alkenyl or alkynyl with up to 16 carbon atoms ; an alkyl group with 2 to 6 carbon atoms substituted by hydroxy, C1-4 alkoxy, phenoxy, halophenoxy, C1-4 alkylphenoxy, C1-4 alkoxyphenoxy, nitrophenoxy, cyanophenoxy, amino or C1-4 alkylthio ; optionally halogen-substituted benzyl, NR3 R4 , CHR3 - COOR4 or CHR3 -CONR4 R5 , whilst R3 , R4 and R5 , which may be identical or different, represent hydrogen or C1-8 alkyl groups, and X1 and X2 , which may be identical or different, represent hydrogen or halogen, and X1 may also represent methyl, wherein in a first step (IV) see diagramm : EP0089517,P20,F1 wherein X1 and X2 are as hereinbefore defined, is reacted with a phenol of formula (VI) see diagramm : EP0089517,P20,F2 wherein n and R1 are as hereinbefore defined, in the presence of an aqueous alkali metal or alkaline earth metal base and in a second step the resulting compound of formula (II) see diagramm : EP0089517,P20,F3 wherein n, R1 , X1 and X2 are as hereinbefore defined, is reacted with an amine of formula H2 NR2 (III) wherein R2 is as hereinbefore defined, characterised in that the first step of the reaction is effected in the presence of a conventional phase transfer catalyst and for the second step an alcohol which contains ether groupings is used as solvent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823209878 DE3209878A1 (en) | 1982-03-18 | 1982-03-18 | METHOD FOR PRODUCING DIPHENYL ETHERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL68142A0 true IL68142A0 (en) | 1983-06-15 |
Family
ID=6158603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL68142A IL68142A0 (en) | 1982-03-18 | 1983-03-16 | Preparation of diphenyl ethers |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0089517B1 (en) |
| JP (1) | JPS58170736A (en) |
| AT (1) | ATE20340T1 (en) |
| CA (1) | CA1264763A (en) |
| DE (2) | DE3209878A1 (en) |
| IL (1) | IL68142A0 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424280A (en) * | 1993-10-07 | 1995-06-13 | American Cyanamid Company | Aryloxybenzene herbicidal agents |
| GB9622345D0 (en) * | 1996-10-28 | 1997-01-08 | Zeneca Ltd | Chemical process |
| WO2009055278A1 (en) * | 2007-10-24 | 2009-04-30 | Dow Agrosciences Llc | Improved process for the manufacture of r-(+)-2-(4-(4-cyano-2-fluorophenoxy)phenoxy)propionic acid esters |
| RS60953B1 (en) | 2013-09-09 | 2020-11-30 | Peloton Therapeutics Inc | Aryl ethers and uses thereof |
| US10807948B2 (en) | 2015-03-11 | 2020-10-20 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
| EP3267792A4 (en) | 2015-03-11 | 2018-09-26 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
| WO2016145045A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating glioblastoma |
| US10155726B2 (en) | 2015-03-11 | 2018-12-18 | Peloton Therapeutics, Inc. | Substituted pyridines and uses thereof |
| WO2016168510A1 (en) | 2015-04-17 | 2016-10-20 | Peloton Therapeutics, Inc. | Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof |
| CN114349647B (en) * | 2021-10-29 | 2024-01-09 | 陕西菲尔特化工有限公司 | Synthesis method of aclonifen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2311004A1 (en) * | 1975-05-13 | 1976-12-10 | Ciba Geigy Ag | PROCESS FOR PREPARING DIARYLIC COMPOUNDS OR HETEROARYLIC COMPOUNDS AND PRODUCTS OBTAINED BY THIS PROCESS |
| DE2938595A1 (en) * | 1979-09-24 | 1981-04-23 | Celamerck Gmbh & Co Kg, 6507 Ingelheim | METHOD FOR PRODUCING DIPHENYL ETHERS |
-
1982
- 1982-03-18 DE DE19823209878 patent/DE3209878A1/en not_active Withdrawn
-
1983
- 1983-02-28 EP EP83101949A patent/EP0089517B1/en not_active Expired
- 1983-02-28 DE DE8383101949T patent/DE3364001D1/en not_active Expired
- 1983-02-28 AT AT83101949T patent/ATE20340T1/en not_active IP Right Cessation
- 1983-03-15 JP JP58044033A patent/JPS58170736A/en active Granted
- 1983-03-16 CA CA000423736A patent/CA1264763A/en not_active Expired - Lifetime
- 1983-03-16 IL IL68142A patent/IL68142A0/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE20340T1 (en) | 1986-06-15 |
| DE3364001D1 (en) | 1986-07-17 |
| EP0089517B1 (en) | 1986-06-11 |
| DE3209878A1 (en) | 1983-09-29 |
| JPH0480898B2 (en) | 1992-12-21 |
| CA1264763A (en) | 1990-01-23 |
| EP0089517A1 (en) | 1983-09-28 |
| JPS58170736A (en) | 1983-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |