IL68142A0 - Preparation of diphenyl ethers - Google Patents
Preparation of diphenyl ethersInfo
- Publication number
- IL68142A0 IL68142A0 IL68142A IL6814283A IL68142A0 IL 68142 A0 IL68142 A0 IL 68142A0 IL 68142 A IL68142 A IL 68142A IL 6814283 A IL6814283 A IL 6814283A IL 68142 A0 IL68142 A0 IL 68142A0
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- formula
- hereinbefore defined
- see diagramm
- alkyl
- Prior art date
Links
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 101100097467 Arabidopsis thaliana SYD gene Proteins 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 101100495925 Schizosaccharomyces pombe (strain 972 / ATCC 24843) chr3 gene Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical class [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- -1 nitrophenoxy, cyanophenoxy, amino Chemical group 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Abstract
1. Process for the preparation of compounds of formula (I) see diagramm : EP0089517,P19,F2 wherein n represents an integer from 1 to 3, if R1 represents hydrogen, halogen or alkyl with 1 to 8 carbon atoms or n represents 1 if R1 represents hydrogen, trifluoromethyl, alkoxy with 1 to 8 carbon atoms or acetyl, R2 represents hydrogen ; alkyl, alkenyl or alkynyl with up to 16 carbon atoms ; an alkyl group with 2 to 6 carbon atoms substituted by hydroxy, C1-4 alkoxy, phenoxy, halophenoxy, C1-4 alkylphenoxy, C1-4 alkoxyphenoxy, nitrophenoxy, cyanophenoxy, amino or C1-4 alkylthio ; optionally halogen-substituted benzyl, NR3 R4 , CHR3 - COOR4 or CHR3 -CONR4 R5 , whilst R3 , R4 and R5 , which may be identical or different, represent hydrogen or C1-8 alkyl groups, and X1 and X2 , which may be identical or different, represent hydrogen or halogen, and X1 may also represent methyl, wherein in a first step (IV) see diagramm : EP0089517,P20,F1 wherein X1 and X2 are as hereinbefore defined, is reacted with a phenol of formula (VI) see diagramm : EP0089517,P20,F2 wherein n and R1 are as hereinbefore defined, in the presence of an aqueous alkali metal or alkaline earth metal base and in a second step the resulting compound of formula (II) see diagramm : EP0089517,P20,F3 wherein n, R1 , X1 and X2 are as hereinbefore defined, is reacted with an amine of formula H2 NR2 (III) wherein R2 is as hereinbefore defined, characterised in that the first step of the reaction is effected in the presence of a conventional phase transfer catalyst and for the second step an alcohol which contains ether groupings is used as solvent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823209878 DE3209878A1 (en) | 1982-03-18 | 1982-03-18 | METHOD FOR PRODUCING DIPHENYL ETHERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL68142A0 true IL68142A0 (en) | 1983-06-15 |
Family
ID=6158603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL68142A IL68142A0 (en) | 1982-03-18 | 1983-03-16 | Preparation of diphenyl ethers |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0089517B1 (en) |
| JP (1) | JPS58170736A (en) |
| AT (1) | ATE20340T1 (en) |
| CA (1) | CA1264763A (en) |
| DE (2) | DE3209878A1 (en) |
| IL (1) | IL68142A0 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424280A (en) * | 1993-10-07 | 1995-06-13 | American Cyanamid Company | Aryloxybenzene herbicidal agents |
| GB9622345D0 (en) * | 1996-10-28 | 1997-01-08 | Zeneca Ltd | Chemical process |
| CN101835742A (en) * | 2007-10-24 | 2010-09-15 | 陶氏益农公司 | Improved process for the preparation of R- (+) -2- (4- (4-cyano-2-fluorophenoxy) phenoxy) propanoic acid esters |
| MX2016002974A (en) | 2013-09-09 | 2016-06-02 | Peloton Therapeutics Inc | Aryl ethers and uses thereof. |
| EP3268362B1 (en) | 2015-03-11 | 2021-10-20 | Peloton Therapeutics, Inc. | Substituted pyridines and uses thereof |
| WO2016145045A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating glioblastoma |
| EP3267792A4 (en) | 2015-03-11 | 2018-09-26 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
| US10807948B2 (en) | 2015-03-11 | 2020-10-20 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
| WO2016168510A1 (en) | 2015-04-17 | 2016-10-20 | Peloton Therapeutics, Inc. | Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof |
| CN114349647B (en) * | 2021-10-29 | 2024-01-09 | 陕西菲尔特化工有限公司 | Synthesis method of aclonifen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2311004A1 (en) * | 1975-05-13 | 1976-12-10 | Ciba Geigy Ag | PROCESS FOR PREPARING DIARYLIC COMPOUNDS OR HETEROARYLIC COMPOUNDS AND PRODUCTS OBTAINED BY THIS PROCESS |
| DE2938595A1 (en) * | 1979-09-24 | 1981-04-23 | Celamerck Gmbh & Co Kg, 6507 Ingelheim | METHOD FOR PRODUCING DIPHENYL ETHERS |
-
1982
- 1982-03-18 DE DE19823209878 patent/DE3209878A1/en not_active Withdrawn
-
1983
- 1983-02-28 AT AT83101949T patent/ATE20340T1/en not_active IP Right Cessation
- 1983-02-28 EP EP83101949A patent/EP0089517B1/en not_active Expired
- 1983-02-28 DE DE8383101949T patent/DE3364001D1/en not_active Expired
- 1983-03-15 JP JP58044033A patent/JPS58170736A/en active Granted
- 1983-03-16 CA CA000423736A patent/CA1264763A/en not_active Expired - Lifetime
- 1983-03-16 IL IL68142A patent/IL68142A0/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3209878A1 (en) | 1983-09-29 |
| DE3364001D1 (en) | 1986-07-17 |
| JPS58170736A (en) | 1983-10-07 |
| JPH0480898B2 (en) | 1992-12-21 |
| EP0089517A1 (en) | 1983-09-28 |
| CA1264763A (en) | 1990-01-23 |
| ATE20340T1 (en) | 1986-06-15 |
| EP0089517B1 (en) | 1986-06-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3364001D1 (en) | Process for the preparation of diphenyl ethers | |
| GB1492362A (en) | M-acyloxyphenyl-1,3-oxazolidenes and methods of synthesis thereof | |
| ES484167A1 (en) | A PROCEDURE TO PREPARE 9- (HIDROXIALCOHIL) -PURINAS | |
| ES8101536A1 (en) | PROCEDURE FOR PREPARING NEW DERIVATIVES OF PLEUROMUTI-LIN | |
| ES8201519A1 (en) | Process for the preparation of diphenyl ethers. | |
| JPS57150442A (en) | Catalyst for introducing alkoxy type substitution group and its manufacture | |
| ES8502681A1 (en) | Process for the preparation of N-allyl-o-alkyl-thioncarbamates. | |
| ES8502107A1 (en) | process for the production of isochromans and indane precursors used in this process. | |
| DK218786D0 (en) | METHOD OF PREPARING 2-CARBOXY-PYRAZINE-4-OXIDES | |
| EP0094612A3 (en) | Novel alkyloxazolylacetic acid derivative, processes for preparation and pharmaceutical compositions containing same | |
| ES8201149A1 (en) | Preparation of glycidyl ether | |
| GB1305547A (en) | ||
| DK184386A (en) | PROCEDURE FOR THE PREPARATION OF 2,2,2-TRIFLUORETHANOL BY HYDROGENOLOGY OF FLUORAL DERIVATIVES | |
| JPS55153790A (en) | Preparation of 7-amino-3-heterocyclic thiomethyl-delta3- cephem-4-carboxylic acid | |
| DK0526318T3 (en) | Process for the preparation of aliphatic asymmetric secondary amines | |
| KR920012048A (en) | Method for preparing optically active esters of quinoxalinyloxyphenoxypropionic acid | |
| ES8105261A1 (en) | Long chain amine derivatives and process for their preparation. | |
| ES278409A1 (en) | Procedure for preparing new amino acids (Machine-translation by Google Translate, not legally binding) | |
| JPS5610149A (en) | Preparation of nitrotoluene derivative | |
| ES469913A1 (en) | 6,11-dihydrodibenzo-(b. e.)-thiepin-11-one-3-aldehyde and 3-acetal derivatives | |
| DE3263287D1 (en) | Process for the preparation of aminoplast resins and their use | |
| JPS55115835A (en) | Preparation of monoalkylresorcinol | |
| GB1516382A (en) | Process for the preparation of 11beta-hydroxy-18-alkyl-estrane compounds | |
| KR870006163A (en) | Method for preparing a new phosphorus-containing sulfur compound | |
| JPS56118027A (en) | Novel preparation of (omega-) -alkyn-1-ol |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |