IL67533A - Preparation of beta-((2-methyl-propoxy)methyl)-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine hydrochloride hydrate - Google Patents

Preparation of beta-((2-methyl-propoxy)methyl)-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine hydrochloride hydrate

Info

Publication number
IL67533A
IL67533A IL67533A IL6753382A IL67533A IL 67533 A IL67533 A IL 67533A IL 67533 A IL67533 A IL 67533A IL 6753382 A IL6753382 A IL 6753382A IL 67533 A IL67533 A IL 67533A
Authority
IL
Israel
Prior art keywords
methyl
pyrrolidineethanamine
phenylmethyl
propoxy
beta
Prior art date
Application number
IL67533A
Other languages
English (en)
Original Assignee
Carter Wallace
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carter Wallace filed Critical Carter Wallace
Publication of IL67533A publication Critical patent/IL67533A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Thermally Insulated Containers For Foods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL67533A 1981-12-28 1982-12-21 Preparation of beta-((2-methyl-propoxy)methyl)-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine hydrochloride hydrate IL67533A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33453581A 1981-12-28 1981-12-28

Publications (1)

Publication Number Publication Date
IL67533A true IL67533A (en) 1986-03-31

Family

ID=23307674

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67533A IL67533A (en) 1981-12-28 1982-12-21 Preparation of beta-((2-methyl-propoxy)methyl)-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine hydrochloride hydrate

Country Status (18)

Country Link
US (1) US4620015A (da)
EP (1) EP0096720B1 (da)
JP (1) JPS58502209A (da)
AT (1) ATE32715T1 (da)
AU (1) AU559555B2 (da)
BR (1) BR8208033A (da)
CA (1) CA1192907A (da)
DE (1) DE3278160D1 (da)
DK (1) DK161143C (da)
ES (1) ES518593A0 (da)
FI (1) FI69304C (da)
IE (1) IE54312B1 (da)
IL (1) IL67533A (da)
IT (1) IT1157249B (da)
NO (1) NO158059C (da)
NZ (1) NZ202857A (da)
PT (1) PT76027B (da)
WO (1) WO1983002274A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU568704B2 (en) * 1983-11-11 1988-01-07 Akzo N.V. Ether of n-propanolamine derivative
GB8330197D0 (en) * 1983-11-11 1983-12-21 Akzo Nv Ether of n-propanolamine derivative
DE3726632A1 (de) * 1987-08-11 1989-05-18 Boehringer Mannheim Gmbh 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE3726633A1 (de) * 1987-08-11 1989-02-23 Boehringer Mannheim Gmbh Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US4888335A (en) * 1988-07-25 1989-12-19 Mcneilab, Inc. 3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents
US5185362A (en) * 1988-09-14 1993-02-09 Mcneilab, Inc. Diphenylamine cardiovascular agents, compositions and use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2568778A (en) * 1948-05-28 1951-09-25 Sterling Drug Inc Tertiary-aminoalkyl-alpha-arylalpha-(4-quinolyl) acetates and amides and their preparation
FR6571M (da) * 1967-08-03 1968-12-23
BE795735A (fr) * 1972-03-06 1973-06-18 Cerm Cent Europ Rech Mauvernay Nouvelles ethylenediamines substituees a activite cardiovasculaire
FR2378024A1 (fr) * 1977-01-25 1978-08-18 Cerm Cent Europ Rech Mauvernay Nouvelle propylamine substituee, obtention et application
CA1085841A (en) * 1976-05-19 1980-09-16 Jean-Marie Ferland Aryloxy proplamines, their preparation and use thereof
FR2376123A1 (fr) * 1977-01-04 1978-07-28 Esteve Intercional Sa Prod Nouveaux derives de 4-tert.butyl-3'-chlorodiphenylamine a activite anti-histaminique, et leur procede de preparation
JPS5429493A (en) * 1977-08-10 1979-03-05 Hitachi Ltd Slat type free flow conveyor

Also Published As

Publication number Publication date
EP0096720A4 (en) 1984-05-29
DK161143B (da) 1991-06-03
DK161143C (da) 1991-11-18
NZ202857A (en) 1986-04-11
ES8402257A1 (es) 1984-02-01
EP0096720B1 (en) 1988-03-02
IT1157249B (it) 1987-02-11
BR8208033A (pt) 1983-11-22
CA1192907A (en) 1985-09-03
FI833016A (fi) 1983-08-23
IE54312B1 (en) 1989-08-16
NO158059C (no) 1988-07-06
JPS58502209A (ja) 1983-12-22
DE3278160D1 (en) 1988-04-07
PT76027A (en) 1983-01-01
DK391983A (da) 1983-08-26
IE823025L (en) 1983-06-28
FI69304B (fi) 1985-09-30
WO1983002274A1 (en) 1983-07-07
FI833016A0 (fi) 1983-08-23
EP0096720A1 (en) 1983-12-28
ES518593A0 (es) 1984-02-01
ATE32715T1 (de) 1988-03-15
FI69304C (fi) 1986-01-10
AU559555B2 (en) 1987-03-12
DK391983D0 (da) 1983-08-26
IT8249760A0 (it) 1982-12-28
PT76027B (en) 1985-11-18
NO158059B (no) 1988-03-28
US4620015A (en) 1986-10-28
NO833071L (no) 1983-08-26

Similar Documents

Publication Publication Date Title
MY109731A (en) Process for preparing aryl piperazinyl-heterocyclic compounds.
JPS56115769A (en) Piperazine derivative and its preparation
IL67533A (en) Preparation of beta-((2-methyl-propoxy)methyl)-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine hydrochloride hydrate
RO87707A (ro) Procedeu pentru prepararea unor saruri de piridiniu
ZA88446B (en) Allylmercaptoacetylsydnonimines,processes for their preparation, and their use
DE3474145D1 (en) Benzothiazolone derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same
EP0779895A4 (en) AN IMPROVED METHOD FOR PRODUCING SIDE CHAIN DERIVATIVES OF CYCLOHEXAPEPTIDYL LIPOPEPTIDES
PL246418A1 (en) Process for preparing n-/3-trifluoromethylphenyl/-n'-propargylpiperazine
KR870003095A (ko) 퀴놀론 카복실산 유도체의 제조방법
GR81759B (da)
HUT40110A (en) Process for preparing indole derivatives
GR81771B (da)
ES484086A1 (es) Procedimiento para la preparacion de compuestos de isopropi-lamina
DK74594A (da) Fremgangsmåde til fremstilling af paroxetin eller et farmaceutisk acceptabelt salt deraf
GB9309321D0 (en) Process for the preparation of ng-monoalkyl-l-arginine derivatives
ES8704922A2 (es) Procedimiento de obtencion de nuevos derivados de -(alquilaminopropionil)-tiofeno sustituidos en el anillo tiofenico

Legal Events

Date Code Title Description
RH Patent void