IL67000A0 - 3-chloropregnane derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
3-chloropregnane derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL67000A0 IL67000A0 IL67000A IL6700082A IL67000A0 IL 67000 A0 IL67000 A0 IL 67000A0 IL 67000 A IL67000 A IL 67000A IL 6700082 A IL6700082 A IL 6700082A IL 67000 A0 IL67000 A0 IL 67000A0
- Authority
- IL
- Israel
- Prior art keywords
- general formula
- image
- derivatives
- chloropregnane
- preparation
- Prior art date
Links
- RCRPCSZLUSZXST-PYASFRJRSA-N (8s,9s,10s,13r,14s,17s)-3-chloro-17-ethyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene Chemical class C1CC2CC(Cl)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CC)[C@@]1(C)CC2 RCRPCSZLUSZXST-PYASFRJRSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 125000002668 chloroacetyl group Chemical group ClCC(=O)* 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- QKZHYYBXLJMLNM-UHFFFAOYSA-N methanimidoyl chloride Chemical class ClC=N QKZHYYBXLJMLNM-UHFFFAOYSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU812976A HU182775B (en) | 1981-10-15 | 1981-10-15 | Process for preparing new 3-chloro-pregnane derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL67000A0 true IL67000A0 (en) | 1983-02-23 |
Family
ID=10961967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67000A IL67000A0 (en) | 1981-10-15 | 1982-10-15 | 3-chloropregnane derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4456601A (en, 2012) |
| EP (1) | EP0077541B1 (en, 2012) |
| JP (1) | JPS5899500A (en, 2012) |
| AT (1) | ATE13676T1 (en, 2012) |
| AU (1) | AU550441B2 (en, 2012) |
| CA (1) | CA1202299A (en, 2012) |
| CS (1) | CS232737B2 (en, 2012) |
| DD (1) | DD204096A5 (en, 2012) |
| DE (1) | DE3264070D1 (en, 2012) |
| HU (1) | HU182775B (en, 2012) |
| IL (1) | IL67000A0 (en, 2012) |
| MX (1) | MX157221A (en, 2012) |
| PL (1) | PL131232B1 (en, 2012) |
| SU (1) | SU1181551A3 (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8403905D0 (sv) * | 1984-07-30 | 1984-07-30 | Draco Ab | Liposomes and steroid esters |
| HU203769B (en) * | 1989-03-09 | 1991-09-30 | Richter Gedeon Vegyeszet | Process for producing new steroide derivatives and pharmaceutical compositions containing them |
| FR2695826B1 (fr) * | 1992-09-21 | 1995-01-06 | Theramex | Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention. |
| HUT72442A (en) * | 1992-12-24 | 1996-04-29 | Rhone Poulenc Rorer Ltd | Steroids condensed with heteroring containing oxygene, pharmaceutical compositions containing them and processes for their production |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2990401A (en) * | 1958-06-18 | 1961-06-27 | American Cyanamid Co | 11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids |
| US2985652A (en) * | 1958-06-17 | 1961-05-23 | Syntex Sa | 3-enol esters of 6-halo-16alpha-hydroxy cortical hormones |
| NL187577C (nl) * | 1978-04-05 | 1991-11-18 | Sibla Srl | 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen. |
-
1981
- 1981-10-15 HU HU812976A patent/HU182775B/hu not_active IP Right Cessation
-
1982
- 1982-10-14 US US06/434,335 patent/US4456601A/en not_active Expired - Fee Related
- 1982-10-14 AU AU89380/82A patent/AU550441B2/en not_active Ceased
- 1982-10-15 AT AT82109551T patent/ATE13676T1/de active
- 1982-10-15 EP EP82109551A patent/EP0077541B1/de not_active Expired
- 1982-10-15 MX MX194824A patent/MX157221A/es unknown
- 1982-10-15 JP JP57181219A patent/JPS5899500A/ja active Granted
- 1982-10-15 DD DD82244042A patent/DD204096A5/de not_active IP Right Cessation
- 1982-10-15 CS CS827364A patent/CS232737B2/cs unknown
- 1982-10-15 CA CA000413492A patent/CA1202299A/en not_active Expired
- 1982-10-15 SU SU823505873A patent/SU1181551A3/ru active
- 1982-10-15 DE DE8282109551T patent/DE3264070D1/de not_active Expired
- 1982-10-15 PL PL1982238641A patent/PL131232B1/pl unknown
- 1982-10-15 IL IL67000A patent/IL67000A0/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL238641A1 (en) | 1983-05-23 |
| JPS5899500A (ja) | 1983-06-13 |
| ATE13676T1 (de) | 1985-06-15 |
| HU182775B (en) | 1984-03-28 |
| AU550441B2 (en) | 1986-03-20 |
| SU1181551A3 (ru) | 1985-09-23 |
| EP0077541B1 (de) | 1985-06-05 |
| EP0077541A1 (de) | 1983-04-27 |
| AU8938082A (en) | 1983-04-21 |
| CS736482A2 (en) | 1984-06-18 |
| CS232737B2 (en) | 1985-02-14 |
| MX157221A (es) | 1988-11-04 |
| US4456601A (en) | 1984-06-26 |
| CA1202299A (en) | 1986-03-25 |
| DE3264070D1 (en) | 1985-07-11 |
| JPH0121840B2 (en, 2012) | 1989-04-24 |
| DD204096A5 (de) | 1983-11-16 |
| PL131232B1 (en) | 1984-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |