IL65556A - Pharmaceutical compositions containing n-(aryloxyalkyl)-n'-(aminoalkyl)ureas or salts thereof and some such novel compounds - Google Patents

Pharmaceutical compositions containing n-(aryloxyalkyl)-n'-(aminoalkyl)ureas or salts thereof and some such novel compounds

Info

Publication number
IL65556A
IL65556A IL65556A IL6555682A IL65556A IL 65556 A IL65556 A IL 65556A IL 65556 A IL65556 A IL 65556A IL 6555682 A IL6555682 A IL 6555682A IL 65556 A IL65556 A IL 65556A
Authority
IL
Israel
Prior art keywords
aryloxyalkyl
ureas
aminoalkyl
salts
pharmaceutical compositions
Prior art date
Application number
IL65556A
Other languages
English (en)
Other versions
IL65556A0 (en
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IL65556A0 publication Critical patent/IL65556A0/xx
Publication of IL65556A publication Critical patent/IL65556A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/08—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL65556A 1981-05-20 1982-04-20 Pharmaceutical compositions containing n-(aryloxyalkyl)-n'-(aminoalkyl)ureas or salts thereof and some such novel compounds IL65556A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26551081A 1981-05-20 1981-05-20

Publications (2)

Publication Number Publication Date
IL65556A0 IL65556A0 (en) 1982-07-30
IL65556A true IL65556A (en) 1985-07-31

Family

ID=23010745

Family Applications (1)

Application Number Title Priority Date Filing Date
IL65556A IL65556A (en) 1981-05-20 1982-04-20 Pharmaceutical compositions containing n-(aryloxyalkyl)-n'-(aminoalkyl)ureas or salts thereof and some such novel compounds

Country Status (22)

Country Link
EP (1) EP0066987B1 (xx)
JP (1) JPS57197215A (xx)
KR (1) KR890001999B1 (xx)
AU (1) AU544977B2 (xx)
CA (1) CA1190228A (xx)
DE (1) DE3272856D1 (xx)
DK (1) DK228582A (xx)
EG (1) EG15911A (xx)
ES (3) ES512338A0 (xx)
FI (1) FI76552C (xx)
GR (1) GR76408B (xx)
HK (1) HK86187A (xx)
HU (1) HU187706B (xx)
IE (1) IE53319B1 (xx)
IL (1) IL65556A (xx)
IN (1) IN156479B (xx)
NO (1) NO153295C (xx)
NZ (1) NZ200668A (xx)
PH (1) PH20208A (xx)
PT (1) PT74931B (xx)
SG (1) SG48887G (xx)
ZA (1) ZA823213B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486344A (en) * 1983-03-28 1984-12-04 Miles Laboratories, Inc. Urea-linked immunogens, antibodies, and preparative method
JPS61126065A (ja) * 1984-11-26 1986-06-13 Mitsui Petrochem Ind Ltd 置換フエノキシ尿素、その製造法およびそれを有効成分として含有する除草剤
US4895840A (en) * 1987-06-10 1990-01-23 A. H. Robins Company, Incorporated N-(aryl-,aryloxy-,arylthio-arylsulfinyl-and arylsulfonyl-)alkyl-N,N'-(or n'n')alkylaminoalkyl ureas and cyanoguanidines
JP2826826B2 (ja) * 1988-04-11 1998-11-18 日本ケミファ株式会社 アルキレンジアミン誘導体
AU2031692A (en) * 1991-07-22 1993-01-28 Zyma S.A. Arylalkylamine derivatives
US8106221B2 (en) 2007-06-20 2012-01-31 Vitae Pharmaceuticals, Inc. Renin inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2344934A (en) * 1943-02-12 1944-03-21 American Cyanamid Co Quaternary nitrogen condensation products of methylol urea ethers
GB1031165A (en) * 1965-08-18 1966-05-25 Wellcome Found Guanidines, isoureas and isothioureas

Also Published As

Publication number Publication date
HU187706B (en) 1986-02-28
EP0066987A2 (en) 1982-12-15
AU544977B2 (en) 1985-06-27
KR830010058A (ko) 1983-12-24
CA1190228A (en) 1985-07-09
NZ200668A (en) 1985-11-08
HK86187A (en) 1987-11-27
GR76408B (xx) 1984-08-10
NO821669L (no) 1982-11-22
EG15911A (en) 1986-09-30
JPS57197215A (en) 1982-12-03
ES8303308A1 (es) 1983-02-01
PT74931B (en) 1983-12-23
PT74931A (en) 1982-06-01
AU8388282A (en) 1982-11-25
EP0066987B1 (en) 1986-08-27
DK228582A (da) 1982-11-21
ES8303306A1 (es) 1983-02-01
ZA823213B (en) 1983-03-30
ES512337A0 (es) 1983-02-01
ES512338A0 (es) 1983-02-01
NO153295C (no) 1986-02-19
NO153295B (no) 1985-11-11
IL65556A0 (en) 1982-07-30
FI76552B (fi) 1988-07-29
ES512335A0 (es) 1983-02-01
FI821775A0 (fi) 1982-05-19
DE3272856D1 (de) 1986-10-02
FI76552C (fi) 1988-11-10
PH20208A (en) 1986-10-20
IE821192L (en) 1982-11-20
ES8303307A1 (es) 1983-02-01
IE53319B1 (en) 1988-10-12
IN156479B (xx) 1985-08-10
SG48887G (en) 1987-07-24
KR890001999B1 (ko) 1989-06-07
EP0066987A3 (en) 1983-09-14

Similar Documents

Publication Publication Date Title
PH20866A (en) N-((4,6-dimethoxypyrimidin-2-yl)aminocarbonyl)-3-trifluoromethylpyridine-2-sulfonamide or salts thereof, herbicidal composition and method of use thereof
PT84737A (en) N-(2(-aminophenyl)-benzamide derivatives process for the preparation thereof and pharmaceutical compositions containing them
IL75038A0 (en) 2-(n-substituted guanidino)-4-heteroarylthiazoles and pharmaceutical compositions containing them
NZ189349A (en) N-phenyl-n'-(2-chloro-6-fluorobenzoyl) ureas and athropodicidal compositions
PT87680A (pt) A process for the preparation of n-(aryl-,arylthio-arylsulfinyl-and arylsulfonyl-n,n'-(or n'n')alkylamino-alkyl ureas and cyanoguanidines and of pharmaceutical compositions containing the same
IL60891A (en) N-(trimethoxybenzyl)-n'-(substituted phenyl)piperazines,their preparation and pharmaceutical compositions comprising them
IL65556A (en) Pharmaceutical compositions containing n-(aryloxyalkyl)-n'-(aminoalkyl)ureas or salts thereof and some such novel compounds
AU572832B2 (en) N-(halo-benzoyl)-n'-(halo-alkenyl-phenyl)-ureas as insecticides
IL70580A (en) N-(phenoxyphenyl or phenoxypyridyl)-n'-benzoyl ureas,substituted at the phenoxy group,process for their preparation and pesticidal compositions containing the same
IL64507A (en) N-(p-aminophenyl)-n'-benzoyl urea derivatives,their production and pesticidal compositions containing them
IL65567A0 (en) N-(arylthioalkyl)-n'-(aminoalkyl)ureas and pharmaceutical compositions containing them
DE3362332D1 (de) N-(aminomethyl-5-oxazolin-2-yl-2)-n'-phenyl ureas
IL74140A0 (en) Substituted n-((amino)alkyl)-1-pyrrolidine,-1-piperidine and-1-homopiperidinecarboxamides and pharmaceutical compositions containing them
NZ192771A (en) N-(4-alkenylthio-phenyl)-n'-benzoylureas and insecticidal compositions
ZA823212B (en) N-(arylthioalkyl)-n'-(aminoalkyl)
KE3663A (en) N-(arylthioalkyl)-n'-(aminoalkyl)ureas
IL92438A0 (en) Amine salts of 1,4,2-oxazaphospholidine-4-acetic acid,2-alkoxy-2-oxides and herbicidal compositions
PT69214A (en) Process for the preparation of an arthropodical or fungicidal composition containing n-(omega-chloroalkanoyl)-n'-trifluoromethylphenyl ureas
IL59019A (en) Pharmaceutical compositions comprising n-aryl-n'-(2-imidazolinylidene)urea compounds,certain such novel compounds and their preparation
KE3735A (en) N-(aryloxyalkyl)-n'-(amino-alkyl)ureas
ZA761477B (en) N-(6-acyloxybenzothiazol-2-yl)-n'-phenyl(or substituted phenyl)ureas
IL70693A (en) N-(2-(1,2-dichlorovinyloxy)phenylsulfonyl)ureas and thioureas,their preparation and bactericidal compositions containing them
IL63099A (en) N-phenyl-n'-(1,4,5,6-tetrahydropyrimidin-2-yl)or(4,5,6,7-tetrahydro-1-h-1,3-diazepin-2-yl))ureas,their preparation and pharmaceutical compositions containing them
IL76579A0 (en) Octahydroindolo(2,3-a)quinoli-zin-1-yl-alkanecarboxylic acid amides and their acid addition salts,their preparation and pharmaceutical compositions containing them
LT2602B (lt) N-(ciklopropiltriazinil)-arba n-(ciklopropilpirimidinil)-n'-arilsulfonilkarbamido gavimo budas