IL65211A - Polypeptide antagonists of arginine vasopressin - Google Patents
Polypeptide antagonists of arginine vasopressinInfo
- Publication number
- IL65211A IL65211A IL65211A IL6521182A IL65211A IL 65211 A IL65211 A IL 65211A IL 65211 A IL65211 A IL 65211A IL 6521182 A IL6521182 A IL 6521182A IL 65211 A IL65211 A IL 65211A
- Authority
- IL
- Israel
- Prior art keywords
- arginine vasopressin
- polypeptide antagonists
- antagonists
- polypeptide
- vasopressin
- Prior art date
Links
- 102400000059 Arg-vasopressin Human genes 0.000 title 1
- 101800001144 Arg-vasopressin Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/15—Oxytocin or vasopressin; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/247,008 US4367225A (en) | 1981-03-24 | 1981-03-24 | Novel antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin |
| US06/322,071 US4399125A (en) | 1981-03-24 | 1981-11-16 | Novel antagonists of the antidiuretic action of arginine vasopressin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL65211A0 IL65211A0 (en) | 1982-05-31 |
| IL65211A true IL65211A (en) | 1986-02-28 |
Family
ID=26938391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL65211A IL65211A (en) | 1981-03-24 | 1982-03-09 | Polypeptide antagonists of arginine vasopressin |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4399125A (ro) |
| EP (1) | EP0061356B1 (ro) |
| KR (1) | KR880000758B1 (ro) |
| AU (1) | AU546865B2 (ro) |
| BG (1) | BG38487A3 (ro) |
| CA (1) | CA1185235A (ro) |
| DD (2) | DD202695A5 (ro) |
| DE (1) | DE3264734D1 (ro) |
| DK (1) | DK130182A (ro) |
| ES (2) | ES8604264A1 (ro) |
| FI (1) | FI77047C (ro) |
| HU (1) | HU189127B (ro) |
| IE (1) | IE52624B1 (ro) |
| IL (1) | IL65211A (ro) |
| NO (1) | NO162024C (ro) |
| NZ (1) | NZ199908A (ro) |
| PH (1) | PH19237A (ro) |
| PT (1) | PT74615B (ro) |
| RO (1) | RO84361B (ro) |
| YU (1) | YU63482A (ro) |
| ZW (1) | ZW4882A1 (ro) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4491577A (en) * | 1981-11-16 | 1985-01-01 | The Medical College Of Ohio | Antagonists of the antidiuretic action of arginine vasopressin |
| DK153883A (da) * | 1982-04-20 | 1983-10-21 | Ceskoslovenska Akademie Ved | Vasopressin-analoge |
| US4587045A (en) * | 1983-02-16 | 1986-05-06 | Smithkline Beckman Corporation | Intermediates for preparing octapeptide vasopressin antagonists |
| US4469679A (en) * | 1983-02-16 | 1984-09-04 | Smithkline Beckman Corporation | Octapeptide vasopressin antagonists |
| US4483794A (en) * | 1983-05-10 | 1984-11-20 | Ceskoslovenska Akademie Ved | Analogs of neurohypophysial hormones |
| CA1238314A (en) * | 1983-09-22 | 1988-06-21 | James F. Callahan | Process for preparing basic heptapeptide vasopressin antagonists |
| US4551445A (en) * | 1983-10-14 | 1985-11-05 | The Medical College Of Ohio | Derivatives of arginine vasopressin antagonists |
| US4649130A (en) * | 1984-01-26 | 1987-03-10 | Medical College Of Ohio | Novel derivatives of arginine vasopressin antagonists |
| US4714696A (en) * | 1984-01-26 | 1987-12-22 | Medical College Of Ohio | Novel derivatives of arginine vasopressin antagonists |
| CA1249397A (en) * | 1984-03-07 | 1989-01-24 | Fadia E. Ali | Process for preparing des-proline vasopressin antagonists |
| US4481193A (en) * | 1984-03-07 | 1984-11-06 | Smithkline Beckman Corporation | Des-proline vasopressin antagonists |
| US4481194A (en) * | 1984-03-07 | 1984-11-06 | Smithkline Beckman Corporation | Des-proline-des-glycine vasopressin antagonists |
| US4597901A (en) * | 1984-12-14 | 1986-07-01 | Smithkline Beckman Corporation | β-indolylalanyl or β-indolylglycinyl vasopressin antagonists |
| US4719199A (en) * | 1984-12-14 | 1988-01-12 | Smithkline Beckman Corporation | Diuretic compositions and methods of producing diuresis |
| US4684716A (en) * | 1984-12-14 | 1987-08-04 | Smithkline Beckman Corporation | Polypeptide intermediates |
| US4624943A (en) * | 1985-03-20 | 1986-11-25 | Smithkline Beckman Corporation | Aromatic basic-tailed vasopressin antagonists |
| WO1987002676A1 (en) * | 1985-10-25 | 1987-05-07 | Gibson-Stephens Neuropharmaceuticals, Inc. | Conformationally constrained oxytocin antagonists with prolonged biological activities |
| PT84342B (pt) * | 1986-02-25 | 1989-09-14 | Smithkline Beecham Corp | Processo de preparacao de compostos de vasopressina |
| US4762820A (en) * | 1986-03-03 | 1988-08-09 | Trustees Of Boston University | Therapeutic treatment for congestive heart failure |
| WO1988005661A1 (en) * | 1987-01-30 | 1988-08-11 | Biomed Research Consultants, Limited | Vasopressin-based pharmaceutical compositions |
| US5055448A (en) * | 1987-06-25 | 1991-10-08 | Medical College Of Ohio | Linear derivatives of arginine vasopressin antagonists |
| AT398766B (de) * | 1988-05-26 | 1995-01-25 | Gebro Broschek Gmbh | Verfahren zur intramolekularen oxidation von zwei -sh gruppen in einer peptidverbindung zu einer disulfidbrücke |
| US5070187A (en) * | 1989-11-03 | 1991-12-03 | Trustees Of Boston University | Pharmacologically effective antagonists of arginine-vasopressin |
| US5051400A (en) * | 1990-06-28 | 1991-09-24 | Smithkline Beecham Corporation | Method of treating nausea and emesis related to motion sickness with vasopressin antagonists |
| RU2342949C1 (ru) * | 2007-03-26 | 2009-01-10 | Юрий Георгиевич Жуковский | Применение [дезамино-1, изолейцин-3, аргинин-8]вазопрессина в качестве средства для увеличения выведения почкой солей натрия и усиления обратного избирательного всасывания из почечных канальцев в кровь воды-растворителя |
| CN111253569B (zh) * | 2020-02-26 | 2021-06-01 | 山东大学 | 一种聚合物、其制剂及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1193509B (de) * | 1960-06-02 | 1965-05-26 | Hoechst Ag | Verfahren zur Herstellung eines neuen Oktapeptids mit vasopressorischer Wirksamkeit |
| CH426861A (de) * | 1963-06-06 | 1966-12-31 | Sandoz Ag | Verfahren zur Herstellung eines bisher unbekannten Polypeptids |
| CH442342A (de) * | 1964-07-17 | 1967-08-31 | Sandoz Ag | Verfahren zur Herstellung eines neuen Polypeptids |
| CH460039A (de) * | 1965-04-15 | 1968-07-31 | Sandoz Ag | Verfahren zur Herstellung eines neuen Polypeptids |
| CH495957A (de) * | 1966-09-15 | 1970-09-15 | Ceskoslovenska Akademie Ved | Verfahren zur Herstellung eines antidiuretisch wirksamen Polypeptids |
| US4148787A (en) * | 1976-05-24 | 1979-04-10 | Ferring Ab | Antidiuretically effective polypeptide and a process for preparing the same |
-
1981
- 1981-11-16 US US06/322,071 patent/US4399125A/en not_active Expired - Fee Related
-
1982
- 1982-03-02 IE IE465/82A patent/IE52624B1/en unknown
- 1982-03-03 CA CA000397464A patent/CA1185235A/en not_active Expired
- 1982-03-04 NZ NZ199908A patent/NZ199908A/xx unknown
- 1982-03-09 IL IL65211A patent/IL65211A/xx unknown
- 1982-03-10 PH PH26975A patent/PH19237A/en unknown
- 1982-03-16 ZW ZW48/82A patent/ZW4882A1/xx unknown
- 1982-03-17 AU AU81617/82A patent/AU546865B2/en not_active Ceased
- 1982-03-18 ES ES510579A patent/ES8604264A1/es not_active Expired
- 1982-03-19 PT PT74615A patent/PT74615B/pt unknown
- 1982-03-23 BG BG055925A patent/BG38487A3/xx unknown
- 1982-03-23 KR KR8201234A patent/KR880000758B1/ko not_active Expired
- 1982-03-23 NO NO820967A patent/NO162024C/no unknown
- 1982-03-23 HU HU82880A patent/HU189127B/hu unknown
- 1982-03-23 RO RO107007A patent/RO84361B/ro unknown
- 1982-03-23 FI FI821019A patent/FI77047C/fi not_active IP Right Cessation
- 1982-03-23 DK DK130182A patent/DK130182A/da not_active Application Discontinuation
- 1982-03-24 DE DE8282301555T patent/DE3264734D1/de not_active Expired
- 1982-03-24 DD DD82238409A patent/DD202695A5/de not_active IP Right Cessation
- 1982-03-24 EP EP82301555A patent/EP0061356B1/en not_active Expired
- 1982-03-24 DD DD82255304A patent/DD212735A5/de not_active IP Right Cessation
- 1982-03-24 YU YU00634/82A patent/YU63482A/xx unknown
-
1985
- 1985-08-14 ES ES546137A patent/ES8703489A1/es not_active Expired
Also Published As
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