IL62660A - 4,5-diaryl-alpha(polyfluoroalkyl)-1h-pyrrole-2-methanamines,their preparation and pharmaceutical compositions containing them - Google Patents

4,5-diaryl-alpha(polyfluoroalkyl)-1h-pyrrole-2-methanamines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL62660A
IL62660A IL62660A IL6266081A IL62660A IL 62660 A IL62660 A IL 62660A IL 62660 A IL62660 A IL 62660A IL 6266081 A IL6266081 A IL 6266081A IL 62660 A IL62660 A IL 62660A
Authority
IL
Israel
Prior art keywords
methanamines
polyfluoroalkyl
diaryl
pyrrole
alpha
Prior art date
Application number
IL62660A
Other languages
English (en)
Other versions
IL62660A0 (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL62660A0 publication Critical patent/IL62660A0/xx
Publication of IL62660A publication Critical patent/IL62660A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL62660A 1980-04-18 1981-04-16 4,5-diaryl-alpha(polyfluoroalkyl)-1h-pyrrole-2-methanamines,their preparation and pharmaceutical compositions containing them IL62660A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14166480A 1980-04-18 1980-04-18
US06/237,638 US4335136A (en) 1980-04-18 1981-03-04 Anti-inflammatory 4,5-diaryl-α-(polyfluoroalkyl)-1H-pyrrole-2-methanamines

Publications (2)

Publication Number Publication Date
IL62660A0 IL62660A0 (en) 1981-06-29
IL62660A true IL62660A (en) 1984-06-29

Family

ID=26839336

Family Applications (1)

Application Number Title Priority Date Filing Date
IL62660A IL62660A (en) 1980-04-18 1981-04-16 4,5-diaryl-alpha(polyfluoroalkyl)-1h-pyrrole-2-methanamines,their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4335136A (fr)
EP (1) EP0038536B1 (fr)
AR (1) AR228270A1 (fr)
AU (1) AU540024B2 (fr)
CA (1) CA1144551A (fr)
DE (1) DE3162089D1 (fr)
DK (1) DK159681A (fr)
ES (1) ES8206465A1 (fr)
FI (1) FI811191L (fr)
GR (1) GR74514B (fr)
HU (1) HU184851B (fr)
IL (1) IL62660A (fr)
NO (1) NO811321L (fr)
NZ (1) NZ196860A (fr)
PH (1) PH16105A (fr)
PT (1) PT72883B (fr)
YU (1) YU100381A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477463A (en) * 1982-05-10 1984-10-16 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalkyl-1H-pyrroles
US4652582A (en) * 1985-01-09 1987-03-24 E. I. Du Pont De Nemours And Company Antiinflammatory-2-halo-4,5-diarylpyrroles
US5908858A (en) 1996-04-05 1999-06-01 Sankyo Company, Limited 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
AU5377698A (en) * 1996-12-10 1998-07-03 G.D. Searle & Co. Substituted pyrrolyl compounds for the treatment of inflammation
CA2316953A1 (fr) 1997-12-26 1999-07-08 Nissin Food Products Co., Ltd. Derives de 5-arylpyrrole
DE19963174A1 (de) * 1999-12-27 2001-07-12 Gruenenthal Gmbh Substituierte Pyrrol-Mannichbasen
DE10261130A1 (de) 2002-12-20 2004-07-01 Grünenthal GmbH Arzneimittel enthaltend substituierte 2,5-Diaminomethyl-1H-pyrrole
FR2874012B1 (fr) * 2004-08-09 2008-08-22 Sanofi Synthelabo Derives de pyrrole, leur preparation et leur utlisation en therapeutique
FR2887548B1 (fr) * 2005-06-27 2007-09-21 Sanofi Aventis Sa Derives de 4,5-diarylpyrrole, leur preparation et leur application en therapeutique
CN101801188A (zh) 2007-07-12 2010-08-11 特拉加拉医药品公司 治疗癌症、肿瘤和肿瘤相关性疾病的方法和组合物
EP3561023B1 (fr) * 2016-12-21 2022-10-12 Kyushu University National University Corporation Matériau luminescent, composé et élément luminescent organique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3564016A (en) * 1968-03-07 1971-02-16 Endo Lab Method of decarbonylation
US3709906A (en) * 1968-07-26 1973-01-09 Sankyo Co 2-alkyl-4,5-diphenylpyrrole derivatives
JPS4838705B1 (fr) * 1969-09-11 1973-11-19
JPS4843117B1 (fr) * 1969-09-16 1973-12-17
DE2062985A1 (de) * 1970-01-23 1971-07-29 Perstorp Ab Verfahren zur Herstellung von stabi len Trioxan Copolymeren
SE435278B (sv) * 1977-12-08 1984-09-17 Sagami Chem Res 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat

Also Published As

Publication number Publication date
IL62660A0 (en) 1981-06-29
GR74514B (fr) 1984-06-29
NO811321L (no) 1981-10-19
AU6963281A (en) 1981-10-22
ES501432A0 (es) 1982-08-16
NZ196860A (en) 1984-05-31
CA1144551A (fr) 1983-04-12
EP0038536A1 (fr) 1981-10-28
YU100381A (en) 1983-12-31
HU184851B (en) 1984-10-29
PH16105A (en) 1983-06-30
FI811191L (fi) 1981-10-19
ES8206465A1 (es) 1982-08-16
EP0038536B1 (fr) 1984-02-01
US4335136A (en) 1982-06-15
AR228270A1 (es) 1983-02-15
DK159681A (da) 1981-10-19
AU540024B2 (en) 1984-10-25
PT72883A (en) 1981-05-01
DE3162089D1 (de) 1984-03-08
PT72883B (en) 1983-02-28

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