PT72883B - Process for preparing antiinflamatory 4,5-diaryl-alpha-(poly- fluoroalxyl)-1h-pyrrole-2-methanamines - Google Patents

Process for preparing antiinflamatory 4,5-diaryl-alpha-(poly- fluoroalxyl)-1h-pyrrole-2-methanamines

Info

Publication number
PT72883B
PT72883B PT72883A PT7288381A PT72883B PT 72883 B PT72883 B PT 72883B PT 72883 A PT72883 A PT 72883A PT 7288381 A PT7288381 A PT 7288381A PT 72883 B PT72883 B PT 72883B
Authority
PT
Portugal
Prior art keywords
fluoroalxyl
methanamines
antiinflamatory
diaryl
pyrrole
Prior art date
Application number
PT72883A
Other languages
English (en)
Other versions
PT72883A (en
Inventor
Saul Carl Cherkofsky
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of PT72883A publication Critical patent/PT72883A/pt
Publication of PT72883B publication Critical patent/PT72883B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT72883A 1980-04-18 1981-04-16 Process for preparing antiinflamatory 4,5-diaryl-alpha-(poly- fluoroalxyl)-1h-pyrrole-2-methanamines PT72883B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14166480A 1980-04-18 1980-04-18
US06/237,638 US4335136A (en) 1980-04-18 1981-03-04 Anti-inflammatory 4,5-diaryl-α-(polyfluoroalkyl)-1H-pyrrole-2-methanamines

Publications (2)

Publication Number Publication Date
PT72883A PT72883A (en) 1981-05-01
PT72883B true PT72883B (en) 1983-02-28

Family

ID=26839336

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72883A PT72883B (en) 1980-04-18 1981-04-16 Process for preparing antiinflamatory 4,5-diaryl-alpha-(poly- fluoroalxyl)-1h-pyrrole-2-methanamines

Country Status (17)

Country Link
US (1) US4335136A (pt)
EP (1) EP0038536B1 (pt)
AR (1) AR228270A1 (pt)
AU (1) AU540024B2 (pt)
CA (1) CA1144551A (pt)
DE (1) DE3162089D1 (pt)
DK (1) DK159681A (pt)
ES (1) ES8206465A1 (pt)
FI (1) FI811191L (pt)
GR (1) GR74514B (pt)
HU (1) HU184851B (pt)
IL (1) IL62660A (pt)
NO (1) NO811321L (pt)
NZ (1) NZ196860A (pt)
PH (1) PH16105A (pt)
PT (1) PT72883B (pt)
YU (1) YU100381A (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477463A (en) * 1982-05-10 1984-10-16 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalkyl-1H-pyrroles
US4652582A (en) * 1985-01-09 1987-03-24 E. I. Du Pont De Nemours And Company Antiinflammatory-2-halo-4,5-diarylpyrroles
US5908858A (en) 1996-04-05 1999-06-01 Sankyo Company, Limited 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
ES2208964T3 (es) * 1996-12-10 2004-06-16 G.D. SEARLE & CO. Compuestos de pirrolilo substituidos para el tratamiento de la inflamacion.
US6294568B1 (en) 1997-12-26 2001-09-25 Nissin Food Products Co., Ltd. 5-arylpyrrole derivatives
DE19963174A1 (de) 1999-12-27 2001-07-12 Gruenenthal Gmbh Substituierte Pyrrol-Mannichbasen
DE10261130A1 (de) * 2002-12-20 2004-07-01 Grünenthal GmbH Arzneimittel enthaltend substituierte 2,5-Diaminomethyl-1H-pyrrole
FR2874012B1 (fr) * 2004-08-09 2008-08-22 Sanofi Synthelabo Derives de pyrrole, leur preparation et leur utlisation en therapeutique
FR2887548B1 (fr) * 2005-06-27 2007-09-21 Sanofi Aventis Sa Derives de 4,5-diarylpyrrole, leur preparation et leur application en therapeutique
CN101801188A (zh) 2007-07-12 2010-08-11 特拉加拉医药品公司 治疗癌症、肿瘤和肿瘤相关性疾病的方法和组合物
EP3561023B1 (en) * 2016-12-21 2022-10-12 Kyushu University National University Corporation Light-emitting material, coumpound, and organic light-emitting element

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3564016A (en) * 1968-03-07 1971-02-16 Endo Lab Method of decarbonylation
US3709906A (en) * 1968-07-26 1973-01-09 Sankyo Co 2-alkyl-4,5-diphenylpyrrole derivatives
JPS4838705B1 (pt) * 1969-09-11 1973-11-19
JPS4843117B1 (pt) * 1969-09-16 1973-12-17
DE2062985A1 (de) * 1970-01-23 1971-07-29 Perstorp Ab Verfahren zur Herstellung von stabi len Trioxan Copolymeren
SE435278B (sv) * 1977-12-08 1984-09-17 Sagami Chem Res 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat

Also Published As

Publication number Publication date
DK159681A (da) 1981-10-19
CA1144551A (en) 1983-04-12
AU6963281A (en) 1981-10-22
IL62660A0 (en) 1981-06-29
IL62660A (en) 1984-06-29
ES501432A0 (es) 1982-08-16
NO811321L (no) 1981-10-19
AU540024B2 (en) 1984-10-25
YU100381A (en) 1983-12-31
DE3162089D1 (de) 1984-03-08
US4335136A (en) 1982-06-15
EP0038536A1 (en) 1981-10-28
GR74514B (pt) 1984-06-29
AR228270A1 (es) 1983-02-15
NZ196860A (en) 1984-05-31
EP0038536B1 (en) 1984-02-01
ES8206465A1 (es) 1982-08-16
FI811191L (fi) 1981-10-19
PT72883A (en) 1981-05-01
HU184851B (en) 1984-10-29
PH16105A (en) 1983-06-30

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