IL60104A - Specific binding assay method using column chromatography and device and test kit therefor - Google Patents

Specific binding assay method using column chromatography and device and test kit therefor

Info

Publication number
IL60104A
IL60104A IL60104A IL6010480A IL60104A IL 60104 A IL60104 A IL 60104A IL 60104 A IL60104 A IL 60104A IL 6010480 A IL6010480 A IL 6010480A IL 60104 A IL60104 A IL 60104A
Authority
IL
Israel
Prior art keywords
species
ligand
binding
bed
column chromatography
Prior art date
Application number
IL60104A
Other languages
English (en)
Original Assignee
Ames Yissum Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ames Yissum Ltd filed Critical Ames Yissum Ltd
Publication of IL60104A publication Critical patent/IL60104A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/528—Monolithic sorbent material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL60104A 1979-06-21 1980-05-16 Specific binding assay method using column chromatography and device and test kit therefor IL60104A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/050,543 US4301139A (en) 1979-06-21 1979-06-21 Multilayer column chromatography specific binding assay method, test device and test kit

Publications (1)

Publication Number Publication Date
IL60104A true IL60104A (en) 1983-03-31

Family

ID=21965858

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60104A IL60104A (en) 1979-06-21 1980-05-16 Specific binding assay method using column chromatography and device and test kit therefor

Country Status (8)

Country Link
US (1) US4301139A (fr)
EP (1) EP0021214B1 (fr)
JP (1) JPS566163A (fr)
AT (1) ATE2807T1 (fr)
AU (1) AU516431B2 (fr)
CA (1) CA1140465A (fr)
DE (1) DE3062332D1 (fr)
IL (1) IL60104A (fr)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
IL56839A0 (en) * 1979-03-11 1979-05-31 Technion Res & Dev Foundation Improvement in specific binding assay technique
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
JPS5782766A (en) * 1980-11-11 1982-05-24 Konishiroku Photo Ind Co Ltd Amynological measuring element
US4425438A (en) * 1981-03-13 1984-01-10 Bauman David S Assay method and device
NZ201901A (en) * 1981-09-25 1986-11-12 Commw Serum Lab Commission An apparatus suitable for performing automated heterogeneous immunoassays in a plurality of samples
US4938927A (en) * 1982-01-08 1990-07-03 Environmental Diagnostics, Inc. Rotary fluid manipulator
US5496520A (en) * 1982-01-08 1996-03-05 Kelton; Arden A. Rotary fluid manipulator
US5141875A (en) * 1982-01-08 1992-08-25 Environmental Diagnostics, Inc. Rotary fluid manipulator
JPS58144743A (ja) * 1982-02-23 1983-08-29 Japan Exlan Co Ltd 活性度の異なるゲルの効率的な併用方法
US4487681A (en) * 1983-01-17 1984-12-11 Chemcut Corporation Electroplating test cell
GB8305197D0 (en) * 1983-02-24 1983-03-30 Amersham Int Plc Assay methods
US4666866A (en) * 1983-04-19 1987-05-19 Krauth Gary H Immunoassay for antigens employing supported binder
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
US4552839A (en) * 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
US4522923A (en) * 1983-10-03 1985-06-11 Genetic Diagnostics Corporation Self-contained assay method and kit
US4786471A (en) * 1983-10-21 1988-11-22 Baxter Travenol Laboratories, Inc. Heterogeneous immunoassay method and assembly
DE3342627A1 (de) * 1983-11-25 1985-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemischer schnelltest
JPS60235060A (ja) * 1984-05-08 1985-11-21 Dai Ichi Pure Chem Co Ltd 放射性物質を利用した迅速免疫測定法
JPS60133368A (ja) * 1983-12-19 1985-07-16 Dai Ichi Pure Chem Co Ltd 免疫測定方法
EP0149168B1 (fr) * 1983-12-19 1991-04-24 Daiichi Pure Chemicals Co. Ltd. Dosage immunologique
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
US4740306A (en) * 1986-03-17 1988-04-26 Temple University - Of The Commonwealth System Of Higher Education Chromatographic column
US5039488A (en) * 1986-06-06 1991-08-13 Genentech, Inc. Devices for amino acid sequence determination
US5223435A (en) * 1986-06-06 1993-06-29 Genetech, Inc. Amino acid sequence determination with mobile peptide
DE3643760A1 (de) * 1986-12-20 1988-06-23 Boehringer Mannheim Gmbh Verfahren zur anreicherung und/oder isolierung von herzglykosiden unter verwendung unpolarer adsorberharze
IL84939A (en) * 1987-01-06 1991-05-12 Baylor College Medicine Chemically inert wafer for synthesizing biopolymers
US4787971A (en) * 1987-01-23 1988-11-29 Alan Donald Miniaturized column chromatography separation apparatus and method of assaying biomolecules employing the same
JPH0746107B2 (ja) 1987-04-27 1995-05-17 ユニリーバー・ナームローゼ・ベンノートシヤープ 検定法
EP0367794A4 (en) * 1987-07-02 1991-03-13 In Vitro Technologies, Inc. Capillary device for immunoassay of multiple analytes
WO1990008957A1 (fr) * 1989-01-30 1990-08-09 Epitope, Inc. Immunoanalyse assistee par avidine-biotine
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5433847A (en) * 1989-11-01 1995-07-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Radial flow chromatography
WO1991013998A1 (fr) * 1990-03-12 1991-09-19 Biosite Diagnostics, Inc. Dispositif d'analyse biologique avec une surface capillaire texturee non absorbante
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5316680A (en) * 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
JPH09507577A (ja) * 1994-01-13 1997-07-29 アビオン ベタイリゲンズ− ウント ベルワルトゥングスゲゼルシャフト ミット ベシュレンクテル ハフツング 多対象同時測定用反応カラムと方法
US5585070A (en) * 1994-04-29 1996-12-17 Phoenix International Life Sciences Inc. Method for extraction, extraction cartridge and automated extraction processing system
US5522994A (en) * 1995-02-01 1996-06-04 Cornell Research Foundation, Inc. Single column chromatographic determination of small molecules in mixtures with large molecules
KR100383141B1 (ko) * 1995-09-01 2003-10-24 오르토- 클리니컬 다이아그노스틱스, 인코포레이티드 바나디움브로모퍼옥시다제를시그날-발생효소로서사용하여특이적결합리간드를결정하기위한분석엘리먼트및방법
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US7067264B2 (en) * 2001-07-23 2006-06-27 Bagaria Padma S Test device for detecting human blood and method of use
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
AU2003213071A1 (en) * 2002-02-13 2003-09-04 Nanostream, Inc. Microfluidic separation column devices and fabrication methods
US7261812B1 (en) 2002-02-13 2007-08-28 Nanostream, Inc. Multi-column separation devices and methods
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7619819B2 (en) * 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
AU2003267192A1 (en) 2002-09-12 2004-04-30 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
CA2499046A1 (fr) 2002-09-12 2004-03-25 Cyvera Corporation Microparticules codees sur la base d'un reseau de diffraction pour experimentations multiplexees
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
NZ543495A (en) * 2003-06-25 2009-04-30 Peregrine Pharmaceuticals Inc Method and apparatus for continuous large-scale radiolabeling of proteins
GB2418627B (en) * 2003-07-14 2008-02-20 Waters Investments Ltd Separation device with integral guard column
US7028536B2 (en) * 2004-06-29 2006-04-18 Nanostream, Inc. Sealing interface for microfluidic device
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
CA2587674A1 (fr) 2004-11-16 2006-05-26 Illumina, Inc. Procedes de diffusion optique de fourier permettant d'encoder des microbilles et procede et appareil correspondants
US7604173B2 (en) 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
US7602952B2 (en) 2004-11-16 2009-10-13 Illumina, Inc. Scanner having spatial light modulator
DE102005024154B3 (de) * 2005-05-23 2007-02-08 Bischoff Analysentechnik und -geräte GmbH Elemente zur Trennung von Substanzen durch Verteilung zwischen einer stationären und einer mobilen Phase und Verfahren zur Herstellung einer Trennvorrichtung
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
KR20090093992A (ko) * 2006-12-21 2009-09-02 해머스미쓰 이마네트 리미티드 미세 제조 장치를 사용하는 친핵 방사성 불화
US20080166792A1 (en) * 2007-01-05 2008-07-10 Attar Amir J Detection of analytes in materials liquids using capillary colorimetric detection
US8283169B1 (en) * 2007-03-21 2012-10-09 Allan Yang Wu Differential gradient separation of cells
DE102007025311A1 (de) 2007-05-30 2008-12-04 Senova Gesellschaft für Biowissenschaft und Technik mbH Quantitativer heterogener schneller Bindungsassay mit breitem dynamischen Bereich und einfacher photometrischer Detektion
CA2721409A1 (fr) * 2008-04-25 2009-10-29 Can Ozbal Cartouches de separation et procedes de fabrication et d'utilisation de ces dernieres
EP2283349A1 (fr) * 2008-04-29 2011-02-16 Becton, Dickinson & Company Procédé et système pour mesurer un échantillon pour déterminer la présence d'un état pathologique et, éventuellement, de le traiter
CN102213717A (zh) * 2010-04-02 2011-10-12 王立莉 免疫纳米粒子层析测定方法及实施该方法的装置
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
JP6443714B2 (ja) * 2013-08-29 2018-12-26 高砂熱学工業株式会社 蒸気生成装置、吸着材収容器、及び蒸気生成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3659104A (en) * 1970-06-29 1972-04-25 Univ Jerusalem The Method of measuring serum thyroxine
US3823001A (en) * 1971-05-06 1974-07-09 Bio Rad Laboratories Determination of thyroid hormone uptake
IL42105A (en) * 1973-04-25 1976-08-31 Yissum Res Dev Co Process for determination of triiodothyronine
US3925017A (en) * 1973-05-01 1975-12-09 Wisconsin Alumni Res Found Preparation of dry, porous gel particles having high water regain for liquid sampling
US3941564A (en) * 1973-09-13 1976-03-02 Miles Laboratories, Inc. Method for assessing thyroid function
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4151254A (en) * 1975-06-16 1979-04-24 Union Carbide Corporation Adsorption columns for use in radioimmunoassays
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
IL51354A (en) * 1977-01-28 1979-07-25 Ames Yissum Ltd Assay method for the quantitative determination of a hapten in aqueous solution
US4189304A (en) * 1978-10-27 1980-02-19 Miles Laboratories, Inc. Device and method for detecting myoglobin

Also Published As

Publication number Publication date
AU5881780A (en) 1981-03-12
EP0021214A1 (fr) 1981-01-07
JPS566163A (en) 1981-01-22
EP0021214B1 (fr) 1983-03-16
AU516431B2 (en) 1981-06-04
CA1140465A (fr) 1983-02-01
US4301139A (en) 1981-11-17
ATE2807T1 (de) 1983-04-15
DE3062332D1 (en) 1983-04-21

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