IL59507A - 5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL59507A IL59507A IL59507A IL5950780A IL59507A IL 59507 A IL59507 A IL 59507A IL 59507 A IL59507 A IL 59507A IL 5950780 A IL5950780 A IL 5950780A IL 59507 A IL59507 A IL 59507A
- Authority
- IL
- Israel
- Prior art keywords
- group
- preparation
- compositions containing
- abeo
- methylergoline
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- -1 piperidinocarbonyl Chemical group 0.000 abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000005117 dialkylcarbamoyl group Chemical group 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000006518 morpholino carbonyl group Chemical group [H]C1([H])OC([H])([H])C([H])([H])N(C(*)=O)C1([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7909281 | 1979-03-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL59507A0 IL59507A0 (en) | 1980-05-30 |
| IL59507A true IL59507A (en) | 1984-01-31 |
Family
ID=10503915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL59507A IL59507A (en) | 1979-03-16 | 1980-02-29 | 5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4317912A (cs) |
| EP (1) | EP0016411B1 (cs) |
| JP (1) | JPS55124784A (cs) |
| AT (1) | ATE1598T1 (cs) |
| AU (1) | AU526978B2 (cs) |
| CA (1) | CA1132555A (cs) |
| CS (1) | CS219272B2 (cs) |
| DE (1) | DE3060888D1 (cs) |
| DK (1) | DK154887C (cs) |
| FI (1) | FI66871C (cs) |
| HU (1) | HU179840B (cs) |
| IE (1) | IE49556B1 (cs) |
| IL (1) | IL59507A (cs) |
| IT (1) | IT1196406B (cs) |
| SU (1) | SU971100A3 (cs) |
| YU (1) | YU70180A (cs) |
| ZA (1) | ZA801505B (cs) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419278D0 (en) * | 1984-07-27 | 1984-08-30 | Lilly Industries Ltd | Pharmaceutical compounds |
| US4835313A (en) * | 1986-03-03 | 1989-05-30 | Merck & Co., Inc. | (5,6-dichloro-3-oxo-9α-propyl-2,3,9,9α-tetrahydrofluoren-7-yl) alkanimidamides |
| US4731472A (en) * | 1986-03-03 | 1988-03-15 | Merck & Co., Inc. | (5,6-dichloro-3-oxo-9A-propyl-2,3,9,9A-tetrahydrofluoren-7-yl)alkanoic acids and alkanimidamides |
| GB8608893D0 (en) * | 1986-04-11 | 1986-05-14 | Erba Farmitalia | D-nor-7-ergoline derivatives |
| GB8617907D0 (en) * | 1986-07-22 | 1986-08-28 | Erba Farmitalia | Tetracyclic indole derivatives |
| US5054490A (en) * | 1988-05-11 | 1991-10-08 | Lunar Corporation | Ultrasonic densitometer device and method |
| GB9407637D0 (en) | 1994-04-18 | 1994-06-08 | Erba Carlo Spa | Serotoninergic abeo-ergoline derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1482871A (en) * | 1922-12-01 | 1924-02-05 | Smith Lulu Teeter | Child's music rack |
| US3393208A (en) * | 1965-10-22 | 1968-07-16 | Mcneilab Inc | 6h-benzo[5, 6] cyclohept[1, 2, 3-cd]indolin-1, 6-diones |
| US3397202A (en) * | 1967-05-02 | 1968-08-13 | Mcneilab Inc | 11, 11alpha-dihydro-11alpha-hydroxy-2-(lower alkyl)-11-r3-6eta-benzo [5, 6] cyclohept [1, 2, 3-cd] indolin-1, 6-diones and intermediates for their preparation |
| GB1482871A (en) * | 1975-03-18 | 1977-08-17 | Farmaceutici Italia | Tetracyclic indole derivatives |
-
1980
- 1980-02-29 IL IL59507A patent/IL59507A/xx unknown
- 1980-03-11 US US06/129,333 patent/US4317912A/en not_active Expired - Lifetime
- 1980-03-11 AU AU56311/80A patent/AU526978B2/en not_active Ceased
- 1980-03-12 AT AT80101273T patent/ATE1598T1/de not_active IP Right Cessation
- 1980-03-12 JP JP3044780A patent/JPS55124784A/ja active Pending
- 1980-03-12 DE DE8080101273T patent/DE3060888D1/de not_active Expired
- 1980-03-12 EP EP80101273A patent/EP0016411B1/en not_active Expired
- 1980-03-13 DK DK108580A patent/DK154887C/da active
- 1980-03-13 CA CA347,558A patent/CA1132555A/en not_active Expired
- 1980-03-14 IE IE541/80A patent/IE49556B1/en unknown
- 1980-03-14 HU HU8080611A patent/HU179840B/hu not_active IP Right Cessation
- 1980-03-14 ZA ZA00801505A patent/ZA801505B/xx unknown
- 1980-03-14 CS CS801783A patent/CS219272B2/cs unknown
- 1980-03-14 FI FI800792A patent/FI66871C/fi not_active IP Right Cessation
- 1980-03-14 YU YU00701/80A patent/YU70180A/xx unknown
- 1980-03-14 IT IT20667/80A patent/IT1196406B/it active
- 1980-03-14 SU SU802892378A patent/SU971100A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| FI66871C (fi) | 1984-12-10 |
| FI800792A7 (fi) | 1980-09-17 |
| IL59507A0 (en) | 1980-05-30 |
| ZA801505B (en) | 1981-05-27 |
| DK154887C (da) | 1989-07-03 |
| EP0016411A2 (en) | 1980-10-01 |
| YU70180A (en) | 1983-02-28 |
| IT8020667A0 (it) | 1980-03-14 |
| SU971100A3 (ru) | 1982-10-30 |
| DK108580A (da) | 1980-09-17 |
| FI66871B (fi) | 1984-08-31 |
| DE3060888D1 (en) | 1982-11-11 |
| AU526978B2 (en) | 1983-02-10 |
| US4317912A (en) | 1982-03-02 |
| CS219272B2 (en) | 1983-03-25 |
| CA1132555A (en) | 1982-09-28 |
| IE800541L (en) | 1980-09-16 |
| DK154887B (da) | 1989-01-02 |
| JPS55124784A (en) | 1980-09-26 |
| IT1196406B (it) | 1988-11-16 |
| HU179840B (en) | 1982-12-28 |
| EP0016411A3 (en) | 1980-11-26 |
| IE49556B1 (en) | 1985-10-30 |
| EP0016411B1 (en) | 1982-09-29 |
| AU5631180A (en) | 1980-09-18 |
| ATE1598T1 (de) | 1982-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK34793A (da) | Vandoploeseligt, farmaceutisk acceptabelt salt af et monoacylderivat af rapamycin, fremgangsmaade til dets fremstilling og injicerbart, farmaceutisk praeparat indeholdende det | |
| SE8000205L (sv) | Nya heterotricykliska derivat, sett for framstellning och anvendning derav sasom lekemedel samt farmaceutiska kompositioner innehallande dessa derivat | |
| ES8609225A1 (es) | Un procedimiento para preparar un derivado de semicarbazida | |
| IL59507A (en) | 5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them | |
| EP0183848A4 (en) | POLYAZAHETEROCYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION. | |
| DE3563048D1 (en) | 2-pyridine-thiol derivatives, processes for their preparation and pharmaceutical compositions containing them | |
| NO150316C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive nitrosoureaderivater | |
| GB1318013A (en) | Nitrofuran and nitrothiophene derivatives | |
| IE39639L (en) | Preparation of n-substituted cycloserine derivatives. | |
| IE35788L (en) | 1, 5-benzodiazepinones. |