IL58592A - 9-(3-(3,5-cis-dimethylpiperazino)propyl)carbazole and salts thereof,their preparation and pharmaceutical composition containing them - Google Patents

9-(3-(3,5-cis-dimethylpiperazino)propyl)carbazole and salts thereof,their preparation and pharmaceutical composition containing them

Info

Publication number
IL58592A
IL58592A IL58592A IL5859279A IL58592A IL 58592 A IL58592 A IL 58592A IL 58592 A IL58592 A IL 58592A IL 5859279 A IL5859279 A IL 5859279A IL 58592 A IL58592 A IL 58592A
Authority
IL
Israel
Prior art keywords
dimethylpiperazino
carbazole
cis
propyl
salts
Prior art date
Application number
IL58592A
Other languages
English (en)
Other versions
IL58592A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL58592A0 publication Critical patent/IL58592A0/xx
Publication of IL58592A publication Critical patent/IL58592A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/86Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL58592A 1978-11-01 1979-10-31 9-(3-(3,5-cis-dimethylpiperazino)propyl)carbazole and salts thereof,their preparation and pharmaceutical composition containing them IL58592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7842845 1978-11-01
US1691479A 1979-03-02 1979-03-02

Publications (2)

Publication Number Publication Date
IL58592A0 IL58592A0 (en) 1980-01-31
IL58592A true IL58592A (en) 1982-12-31

Family

ID=26269424

Family Applications (1)

Application Number Title Priority Date Filing Date
IL58592A IL58592A (en) 1978-11-01 1979-10-31 9-(3-(3,5-cis-dimethylpiperazino)propyl)carbazole and salts thereof,their preparation and pharmaceutical composition containing them

Country Status (15)

Country Link
US (1) US4379160A (ko)
EP (2) EP0012208B1 (ko)
KR (2) KR860001253B1 (ko)
AU (1) AU537630B2 (ko)
BG (1) BG33279A3 (ko)
CA (1) CA1141384A (ko)
DD (1) DD147110A5 (ko)
DK (1) DK460879A (ko)
GR (1) GR69858B (ko)
IE (1) IE48979B1 (ko)
IL (1) IL58592A (ko)
MC (1) MC1286A1 (ko)
MY (1) MY8500221A (ko)
NZ (1) NZ191987A (ko)
PH (1) PH14576A (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469868A (en) * 1982-05-24 1984-09-04 Warner-Lambert Company Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
US5116995A (en) * 1990-05-25 1992-05-26 Taisho Pharmaceutical Co., Ltd. Carbazole compounds
CA2187542C (en) * 1994-04-18 2000-02-01 Nobuyuki Takahashi Adamantane derivative, process for producing the same, and use thereof
US6025355A (en) * 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
EP0844244A1 (en) * 1996-11-22 1998-05-27 Eli Lilly And Company Drug resistance and multidrug resistance modulators
EP1094063A1 (en) 1999-10-18 2001-04-25 Applied Research Systems ARS Holding N.V. 9-(Piperazinylalkyl)carbazoles as Bax-modulators
GB0619398D0 (en) * 2006-10-02 2006-11-08 Univ Dundee Manufacture of rimcazole
GB0907973D0 (en) 2009-05-08 2009-06-24 Modern Biosciences Plc Combination therapy
WO2021236879A1 (en) 2020-05-20 2021-11-25 The Board Of Trustees Of The University Of Illinois Method for treating lysosomal storage diseases with histatin peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE537690A (ko) * 1954-07-01
DE2339396C2 (de) * 1973-08-03 1984-06-28 Boehringer Mannheim Gmbh, 6800 Mannheim N-substituierte 1-Amino-3-phenoxypropan-2-ole, deren Salze, Verfahren zu deren Herstellung sowie Arzneimittel, die diese Verbindungen enthalten

Also Published As

Publication number Publication date
US4379160A (en) 1983-04-05
EP0051321B1 (en) 1986-03-26
EP0051321A1 (en) 1982-05-12
GR69858B (ko) 1982-07-19
EP0012208A2 (en) 1980-06-25
IE792083L (en) 1980-05-01
BG33279A3 (en) 1983-01-14
MY8500221A (en) 1985-12-31
AU537630B2 (en) 1984-07-05
EP0012208A3 (en) 1980-07-23
IL58592A0 (en) 1980-01-31
EP0012208B1 (en) 1983-01-26
AU5237879A (en) 1980-06-12
IE48979B1 (en) 1985-06-26
KR840004689A (ko) 1984-10-22
KR860001252B1 (ko) 1986-09-01
NZ191987A (en) 1984-10-19
DD147110A5 (de) 1981-03-18
DK460879A (da) 1980-05-02
KR840004688A (ko) 1984-10-22
KR860001253B1 (ko) 1986-09-01
CA1141384A (en) 1983-02-15
PH14576A (en) 1981-09-24
MC1286A1 (fr) 1980-07-22

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