IL57115A - Hydrazone-beta-lactam antibiotics,their production and pharmaceutical compositions containing them - Google Patents

Hydrazone-beta-lactam antibiotics,their production and pharmaceutical compositions containing them

Info

Publication number
IL57115A
IL57115A IL57115A IL5711579A IL57115A IL 57115 A IL57115 A IL 57115A IL 57115 A IL57115 A IL 57115A IL 5711579 A IL5711579 A IL 5711579A IL 57115 A IL57115 A IL 57115A
Authority
IL
Israel
Prior art keywords
hydrazone
beta
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL57115A
Other languages
English (en)
Other versions
IL57115A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL57115A0 publication Critical patent/IL57115A0/xx
Publication of IL57115A publication Critical patent/IL57115A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL57115A 1978-04-26 1979-04-23 Hydrazone-beta-lactam antibiotics,their production and pharmaceutical compositions containing them IL57115A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782818263 DE2818263A1 (de) 1978-04-26 1978-04-26 Beta-lactamantibiotika

Publications (2)

Publication Number Publication Date
IL57115A0 IL57115A0 (en) 1979-07-25
IL57115A true IL57115A (en) 1982-04-30

Family

ID=6038043

Family Applications (1)

Application Number Title Priority Date Filing Date
IL57115A IL57115A (en) 1978-04-26 1979-04-23 Hydrazone-beta-lactam antibiotics,their production and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4386089A (xx)
EP (1) EP0004956B1 (xx)
JP (1) JPS54145694A (xx)
AR (1) AR226036A1 (xx)
AT (1) AT367763B (xx)
AU (1) AU4637879A (xx)
CA (1) CA1135687A (xx)
DE (2) DE2818263A1 (xx)
DK (1) DK168879A (xx)
EG (1) EG14265A (xx)
ES (1) ES479919A1 (xx)
FI (1) FI791327A (xx)
GR (1) GR74067B (xx)
HU (1) HU181657B (xx)
IL (1) IL57115A (xx)
NO (1) NO791246L (xx)
NZ (1) NZ190255A (xx)
PT (1) PT69535A (xx)
ZA (1) ZA791986B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3021373A1 (de) * 1980-06-06 1981-12-17 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-n-(imidazolidin-2-on-1-yl)2-iminoacetylcephalosporinen der syn-form
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
IT1211080B (it) * 1981-07-21 1989-09-29 Craf Sud Idrazonocefem derivati biologicamente attivi.
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
US4855420A (en) * 1983-06-03 1989-08-08 Ici Pharma Cephalosporin derivatives
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
GB8318846D0 (en) * 1983-07-12 1983-08-10 Fujisawa Pharmaceutical Co Prophylactic/therapeutic agent against fish diseases
DK429986A (da) * 1985-09-09 1987-03-10 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser
IE862850L (en) * 1985-11-21 1987-05-21 Inst Animal Health Ltd Intermediates for the preparation of beta-lactam antibiotics
KR960002856B1 (ko) * 1987-03-09 1996-02-27 오쓰까 세이야꾸 가부시끼가이샤 2-옥사-이소세펨 화합물, 이를 함유하는 조성물 및 이의 제조방법
DK582788A (da) * 1987-10-22 1989-04-23 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, midler der indeholder dem og fremgangsmaader til fremstilling af dem
JP2845789B2 (ja) * 1995-12-25 1999-01-13 株式会社トクヤマ アミノチアゾール酢酸誘導体の製造方法
EP2105435A4 (en) * 2007-01-10 2011-06-15 Mitsubishi Tanabe Pharma Corp Hydrazone derivatives
CN112094247A (zh) * 2020-08-21 2020-12-18 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） 头孢菌素类药物中间体及其合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1208014A (en) * 1967-03-23 1970-10-07 Glaxo Lab Ltd Cephalosporins
GB1208015A (en) * 1967-03-23 1970-10-07 Glaxo Lab Ltd Cephalosporins
FR2191557A5 (en) * 1972-06-29 1974-02-01 Aries Robert Alpha-(nitro-furfurylidene hydrazino) benzyl penicillins - with broad-spec-trum antibacterial activity
US4107304A (en) * 1974-02-18 1978-08-15 Bayer Aktiengesellschaft Oxo-imidazolidine substituted cephalosporins and antibacterial compositions and methods of combatting bacteria employing them
FR2265391B1 (xx) * 1974-04-02 1978-11-03 Isf Spa
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
US4091212A (en) * 1976-11-26 1978-05-23 E. R. Squibb & Sons, Inc. Hydrazinocarbonylamino cephalosporins 3-heterocyclicthio 7-hydrazinocarbonylamino acetylamino cephalosporins
IT1081810B (it) * 1977-06-07 1985-05-21 Isf Spa Idrazono penicilline
IT1081809B (it) * 1977-06-07 1985-05-21 Isf Spa Idrazono cefalosporine
IT1192287B (it) * 1977-11-14 1988-03-31 Fujisawa Pharmaceutical Co Derivati di acido cefalosporanico ad azione farmaceutica e relativo procedimento di preparazione

Also Published As

Publication number Publication date
IL57115A0 (en) 1979-07-25
ATA306679A (de) 1981-12-15
ZA791986B (en) 1980-05-28
US4386089A (en) 1983-05-31
FI791327A (fi) 1979-10-27
EP0004956A1 (de) 1979-10-31
CA1135687A (en) 1982-11-16
EG14265A (en) 1984-03-31
AT367763B (de) 1982-07-26
ES479919A1 (es) 1979-11-16
NO791246L (no) 1979-10-29
GR74067B (xx) 1984-06-06
EP0004956B1 (de) 1981-10-14
DE2960973D1 (en) 1981-12-24
AU4637879A (en) 1979-11-01
HU181657B (en) 1983-10-28
JPS54145694A (en) 1979-11-14
DK168879A (da) 1979-10-27
AR226036A1 (es) 1982-05-31
PT69535A (en) 1979-05-01
NZ190255A (en) 1981-05-15
DE2818263A1 (de) 1979-11-08

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