IL53606A - 9-(2,6-dihalo-4-methoxy-5-methylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetrane compounds,their manufacture and pharamceutical compositions containing them - Google Patents

9-(2,6-dihalo-4-methoxy-5-methylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetrane compounds,their manufacture and pharamceutical compositions containing them

Info

Publication number
IL53606A
IL53606A IL53606A IL5360677A IL53606A IL 53606 A IL53606 A IL 53606A IL 53606 A IL53606 A IL 53606A IL 5360677 A IL5360677 A IL 5360677A IL 53606 A IL53606 A IL 53606A
Authority
IL
Israel
Prior art keywords
tetrane
nona
dihalo
methylphenyl
methoxy
Prior art date
Application number
IL53606A
Other languages
English (en)
Other versions
IL53606A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT944476A external-priority patent/AT351515B/de
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Priority to IL59722A priority Critical patent/IL59722A/xx
Publication of IL53606A0 publication Critical patent/IL53606A0/xx
Publication of IL53606A publication Critical patent/IL53606A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C07C45/43Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis of >CX2 groups, X being halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5428Acyclic unsaturated phosphonium compounds
IL53606A 1976-12-20 1977-12-14 9-(2,6-dihalo-4-methoxy-5-methylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetrane compounds,their manufacture and pharamceutical compositions containing them IL53606A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL59722A IL59722A (en) 1976-12-20 1977-12-14 2,6dihalo-4-methoxy-5-methyl-benzaldehydes and 5-(2,6,-dihalo-4-methoxy -5-methylphenyl)-penta-2,4-dienals

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT944476A AT351515B (de) 1976-12-20 1976-12-20 Verfahren zur herstellung von neuen polyenver- bindungen
CH1238877A CH630329A5 (en) 1976-12-20 1977-10-11 Process for the preparation of novel polyene compounds.

Publications (2)

Publication Number Publication Date
IL53606A0 IL53606A0 (en) 1978-03-10
IL53606A true IL53606A (en) 1981-07-31

Family

ID=25605535

Family Applications (2)

Application Number Title Priority Date Filing Date
IL53606A IL53606A (en) 1976-12-20 1977-12-14 9-(2,6-dihalo-4-methoxy-5-methylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetrane compounds,their manufacture and pharamceutical compositions containing them
IL59722A IL59722A0 (en) 1976-12-20 1980-03-26 2,6-dihalo-4-methoxy-5-benzaldehydes and 5-(2',6'-dihalo-4'-methoxy-phenyl)-pent-2,4-dienals

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL59722A IL59722A0 (en) 1976-12-20 1980-03-26 2,6-dihalo-4-methoxy-5-benzaldehydes and 5-(2',6'-dihalo-4'-methoxy-phenyl)-pent-2,4-dienals

Country Status (25)

Country Link
US (2) US4225527A (es)
JP (1) JPS6027656B2 (es)
AR (1) AR219727A1 (es)
AU (1) AU520755B2 (es)
CA (1) CA1111441A (es)
DE (1) DE2756652A1 (es)
DK (1) DK155933C (es)
ES (1) ES465215A1 (es)
FI (1) FI66835C (es)
FR (1) FR2374291B1 (es)
GB (3) GB1583799A (es)
GR (1) GR72588B (es)
HU (1) HU179201B (es)
IE (1) IE46216B1 (es)
IL (2) IL53606A (es)
IT (1) IT1089770B (es)
LU (1) LU78712A1 (es)
MC (1) MC1175A1 (es)
MY (1) MY8500247A (es)
NL (1) NL177822C (es)
NO (1) NO145095C (es)
PH (3) PH13565A (es)
PT (1) PT67427B (es)
SE (1) SE436565B (es)
YU (1) YU40911B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171318A (en) * 1978-08-24 1979-10-16 Hoffmann-La Roche Inc. Fluorinated polyenes
US4200647A (en) * 1977-12-21 1980-04-29 Hoffmann-La Roche Inc. Vitamin A compositions to treat rheumatic disease
US4216312A (en) * 1978-08-24 1980-08-05 Hoffmann-La Roche Inc. Furyl substituted polyenes
CH651007A5 (de) * 1982-06-24 1985-08-30 Hoffmann La Roche Polyenverbindungen.
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4539154A (en) * 1983-06-15 1985-09-03 Hoffmann-La Roche Inc. Polyene compounds
US4843096A (en) * 1985-06-26 1989-06-27 Stiefel Laboratories, Inc. Treatment of acne
DE19723480A1 (de) * 1997-06-04 1998-12-10 Basf Ag Verfahren zur Herstellung von Zeaxanthin, Zwischenprodukte für dieses Verfahren und Verfahren zu deren Herstellung
US6273144B1 (en) * 2001-05-16 2001-08-14 Atlantic Richfield Company Method for inhibiting external corrosion on an insulated pipeline
WO2016042573A1 (en) * 2014-09-17 2016-03-24 Emcure Pharmaceuticals Limited Process for preparation of acitretin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2059480A1 (en) 1969-07-04 1971-06-04 Hoffmann La Roche Anticarcinogenic compns contng vitamin a - acids
PH9210A (en) 1969-07-04 1975-07-03 W Bollag Method for the treatment of carsinomas utilizing compositions containing vitamin a acid compounds
BE752927A (fr) 1969-07-04 1971-01-04 Hoffmann La Roche Utilisation de composes polyeniques
US3950418A (en) * 1970-02-02 1976-04-13 Hoffmann-La Roche Inc. Vitamin A acid amides
ZA71145B (en) 1970-02-02 1971-10-27 Hoffmann La Roche Use of vitamin a-acid
US3781314A (en) * 1971-07-14 1973-12-25 Hoffmann La Roche Polyene compounds
US3845089A (en) * 1972-07-27 1974-10-29 Zoecon Corp Phenylheptadienoates
CH585166A5 (es) 1973-03-30 1977-02-28 Hoffmann La Roche
CH589619A5 (es) 1973-08-24 1977-07-15 Hoffmann La Roche
CH585709A5 (es) * 1973-08-24 1977-03-15 Hoffmann La Roche
US4054589A (en) * 1974-09-26 1977-10-18 Hoffmann-La Roche Inc. Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraene esters
CH605562A5 (es) * 1974-09-26 1978-09-29 Hoffmann La Roche
NO144453C (no) * 1974-09-27 1981-09-02 Hoffmann La Roche Analogifremgangsmaate ved fremstilling av farmakodynamiske polyenforbindelser.
JPS609493B2 (ja) * 1976-01-01 1985-03-11 エフ・ホフマン・ラ・ロツシユ・ウント・カンパニ−・アクチエンゲゼルシヤフト ポリエン化合物

Also Published As

Publication number Publication date
ES465215A1 (es) 1978-11-16
AU3149377A (en) 1979-06-21
SE436565B (sv) 1985-01-07
AU520755B2 (en) 1982-02-25
PH13565A (en) 1980-06-26
NO145095B (no) 1981-10-05
JPS5377034A (en) 1978-07-08
AR219727A1 (es) 1980-09-15
FI66835C (fi) 1984-12-10
NL177822B (nl) 1985-07-01
FR2374291A1 (es) 1978-07-13
CA1111441A (en) 1981-10-27
IT1089770B (it) 1985-06-18
NL177822C (nl) 1985-12-02
SE7714463L (sv) 1978-06-21
GB1583798A (en) 1981-02-04
FI773517A (fi) 1978-06-21
DK155933C (da) 1989-12-11
LU78712A1 (es) 1979-02-02
IE46216B1 (en) 1983-04-06
DK155933B (da) 1989-06-05
YU40911B (en) 1986-08-31
IL53606A0 (en) 1978-03-10
NO774373L (no) 1978-06-21
US4267382A (en) 1981-05-12
PT67427B (en) 1979-12-19
FI66835B (fi) 1984-08-31
YU285977A (en) 1984-04-30
PT67427A (en) 1978-01-01
US4225527A (en) 1980-09-30
MY8500247A (en) 1985-12-31
GR72588B (es) 1983-11-18
NO145095C (no) 1982-01-27
FR2374291B1 (es) 1980-03-14
JPS6027656B2 (ja) 1985-06-29
IE772538L (en) 1978-06-20
GB1583800A (en) 1981-02-04
HU179201B (en) 1982-09-28
GB1583799A (en) 1981-02-04
DE2756652C2 (es) 1987-09-03
NL7713602A (nl) 1978-06-22
DE2756652A1 (de) 1978-06-22
MC1175A1 (fr) 1978-09-25
IL59722A0 (en) 1980-06-30
PH13908A (en) 1980-10-27
PH14788A (en) 1981-12-09
DK566977A (da) 1978-06-21

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