IL53420A - Oxepane derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Oxepane derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL53420A
IL53420A IL53420A IL5342077A IL53420A IL 53420 A IL53420 A IL 53420A IL 53420 A IL53420 A IL 53420A IL 5342077 A IL5342077 A IL 5342077A IL 53420 A IL53420 A IL 53420A
Authority
IL
Israel
Prior art keywords
oxepane
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL53420A
Other languages
English (en)
Other versions
IL53420A0 (en
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IL53420A0 publication Critical patent/IL53420A0/xx
Publication of IL53420A publication Critical patent/IL53420A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/04—Seven-membered rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL53420A 1976-11-18 1977-11-17 Oxepane derivatives,their preparation and pharmaceutical compositions containing them IL53420A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/742,940 US4102895A (en) 1976-11-18 1976-11-18 Oxepanes

Publications (2)

Publication Number Publication Date
IL53420A0 IL53420A0 (en) 1978-01-31
IL53420A true IL53420A (en) 1983-05-15

Family

ID=24986860

Family Applications (1)

Application Number Title Priority Date Filing Date
IL53420A IL53420A (en) 1976-11-18 1977-11-17 Oxepane derivatives,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US4102895A (fr)
JP (1) JPS5365890A (fr)
AT (1) AT363478B (fr)
AU (1) AU516476B2 (fr)
CA (1) CA1113478A (fr)
CH (3) CH627469A5 (fr)
DE (1) DE2751396A1 (fr)
FR (1) FR2371443A1 (fr)
GB (1) GB1594100A (fr)
GR (1) GR63241B (fr)
IE (1) IE45915B1 (fr)
IL (1) IL53420A (fr)
NZ (1) NZ185641A (fr)
PH (1) PH13596A (fr)
ZA (1) ZA776879B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177194A (en) * 1978-06-29 1979-12-04 Ortho Pharmaceutical Corporation Total synthesis of the utero-evacuant substance D,L-zoapatanol
US4182717A (en) * 1978-06-29 1980-01-08 Ortho Pharmaceutical Corp. Total synthesis of the utero-evacuant substance d,l-zoapatanol
US4256644A (en) * 1978-12-18 1981-03-17 Ortho Pharmaceutical Corporation Chemical intermediates in the preparation of oxepane compounds
US4215048A (en) * 1979-05-18 1980-07-29 Ortho Pharmaceutical Corporation Total synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4237054A (en) * 1979-05-18 1980-12-02 Ortho Pharmaceutical Corporation Total synthesis of (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1] octane-1-acetic acid
US4237055A (en) * 1979-06-18 1980-12-02 Ortho Pharmaceutical Corporation Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4322353A (en) * 1980-04-18 1982-03-30 Ortho Pharmaceutical Corporation Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes
US4284565A (en) * 1980-05-02 1981-08-18 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl)-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and related compounds
US4329288A (en) * 1980-05-02 1982-05-11 Ortho Pharmaceutical Corporation (1RS,4SR,5RS)-4-(5-Hydroxy-4,8-dimethyl-8-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
KR850000218B1 (ko) * 1980-07-31 1985-03-06 오오소오 화아마슈이티갈 코오포레이숀 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법
US4307019A (en) * 1980-08-25 1981-12-22 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS,-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4277401A (en) * 1980-08-25 1981-07-07 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl)-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4360467A (en) * 1981-02-23 1982-11-23 Ortho Pharmaceutical Corporation Process for preparing 8-oxabicyclo[3.2.1]-octane-1-acetic acids
US4322357A (en) * 1981-02-23 1982-03-30 Ortho Pharmaceutical Corporation Novel cycloheptanes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2515670C2 (de) * 1975-04-10 1985-07-25 Ortho Pharmaceutical Corp., Raritan, N.J. Verfahren zum Isolieren von Substanzen mit uteroevakuierender Wirkung aus der Zoapatl-Pflanze und diese Substanzen enthaltende Arzneimittel

Also Published As

Publication number Publication date
NZ185641A (en) 1984-08-24
CA1113478A (fr) 1981-12-01
CH629792A5 (fr) 1982-05-14
AT363478B (de) 1981-08-10
AU3072977A (en) 1979-05-24
DE2751396A1 (de) 1978-05-24
US4102895A (en) 1978-07-25
IL53420A0 (en) 1978-01-31
JPS5365890A (en) 1978-06-12
IE45915B1 (en) 1982-12-29
FR2371443A1 (fr) 1978-06-16
ATA824077A (de) 1981-01-15
JPS625154B2 (fr) 1987-02-03
CH629793A5 (fr) 1982-05-14
PH13596A (en) 1980-08-05
GB1594100A (en) 1981-07-30
IE45915L (en) 1978-05-18
GR63241B (en) 1979-10-12
FR2371443B1 (fr) 1984-02-24
CH627469A5 (fr) 1982-01-15
AU516476B2 (en) 1981-06-04
ZA776879B (en) 1979-06-27

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