IL52731A0 - Novel amide derivatives of vlb leurosidine leurocristine and related dimeric alkaloids - Google Patents

Novel amide derivatives of vlb leurosidine leurocristine and related dimeric alkaloids

Info

Publication number
IL52731A0
IL52731A0 IL52731A IL5273177A IL52731A0 IL 52731 A0 IL52731 A0 IL 52731A0 IL 52731 A IL52731 A IL 52731A IL 5273177 A IL5273177 A IL 5273177A IL 52731 A0 IL52731 A0 IL 52731A0
Authority
IL
Israel
Prior art keywords
leurocristine
leurosidine
vlb
amide derivatives
novel amide
Prior art date
Application number
IL52731A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL52731A0 publication Critical patent/IL52731A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL52731A 1976-09-08 1977-08-15 Novel amide derivatives of vlb leurosidine leurocristine and related dimeric alkaloids IL52731A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08

Publications (1)

Publication Number Publication Date
IL52731A0 true IL52731A0 (en) 1977-10-31

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52731A IL52731A0 (en) 1976-09-08 1977-08-15 Novel amide derivatives of vlb leurosidine leurocristine and related dimeric alkaloids

Country Status (27)

Country Link
JP (1) JPS5340799A (es)
AR (3) AR226411A1 (es)
AT (1) AT360513B (es)
AU (1) AU511055B2 (es)
BE (1) BE858451A (es)
CA (1) CA1082179A (es)
CH (1) CH631990A5 (es)
DD (1) DD133055A5 (es)
DE (1) DE2739443A1 (es)
DK (1) DK146822C (es)
ES (1) ES462229A1 (es)
FR (1) FR2364220A1 (es)
GB (1) GB1586709A (es)
GR (1) GR69783B (es)
HU (1) HU180722B (es)
IE (1) IE45558B1 (es)
IL (1) IL52731A0 (es)
MX (1) MX4740E (es)
NL (1) NL7709806A (es)
NZ (1) NZ184932A (es)
PH (1) PH14771A (es)
PL (1) PL104309B1 (es)
PT (1) PT66984B (es)
RO (3) RO77921A (es)
SE (1) SE434953B (es)
YU (1) YU209777A (es)
ZA (1) ZA774988B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Also Published As

Publication number Publication date
ZA774988B (en) 1979-03-28
RO77922A (ro) 1981-12-25
ATA644277A (de) 1980-06-15
CH631990A5 (en) 1982-09-15
CA1082179A (en) 1980-07-22
PT66984B (en) 1979-02-13
PH14771A (en) 1981-12-09
FR2364220A1 (fr) 1978-04-07
JPS624398B2 (es) 1987-01-30
SE434953B (sv) 1984-08-27
NZ184932A (en) 1979-11-01
YU209777A (en) 1982-08-31
IE771700L (en) 1978-03-08
IE45558B1 (en) 1982-09-22
AU2803977A (en) 1979-02-22
BE858451A (fr) 1978-03-07
GR69783B (es) 1982-07-07
PL200607A1 (pl) 1978-05-22
HU180722B (en) 1983-04-29
DE2739443C2 (es) 1991-08-14
RO77921A (ro) 1981-12-25
MX4740E (es) 1982-08-25
GB1586709A (en) 1981-03-25
PL104309B1 (pl) 1979-08-31
DE2739443A1 (de) 1978-03-09
FR2364220B1 (es) 1980-04-25
PT66984A (en) 1977-10-01
RO72474A (ro) 1982-05-10
ES462229A1 (es) 1978-07-16
AR231643A1 (es) 1985-01-31
JPS5340799A (en) 1978-04-13
NL7709806A (nl) 1978-03-10
AT360513B (de) 1981-01-12
DD133055A5 (de) 1978-11-29
DK398577A (da) 1978-03-09
SE7710059L (sv) 1978-03-09
AR230642A1 (es) 1984-05-31
DK146822C (da) 1984-06-25
AU511055B2 (en) 1980-07-24
AR226411A1 (es) 1982-07-15
DK146822B (da) 1984-01-16

Similar Documents

Publication Publication Date Title
PH13623A (en) Amide derivatives of vinblastine,leurosidine and leurocristine
DE2860749D1 (en) Dipeptide derivatives of 7-(n-alpha-substituted or non-substituted x-arginyl)-amino-4-methyl-coumarin
PH20036A (en) Derivatives of 4-desacetyl indole-dihydroindole alkaloids
IL48685A0 (en) Novel amide derivatives of vlb,leurosidine,leurocristine and related dimeric alkaloid
IL52731A0 (en) Novel amide derivatives of vlb leurosidine leurocristine and related dimeric alkaloids
GB1547039A (en) Preparation of vincamine and related alkaloids
AU514744B2 (en) Derivatives of vincamine and arovincamine
GB1551054A (en) Syntheses of vinblastine vincristine and vinrosidine
IL54704A (en) Preparation of alkaloids of the leurosine type
ZA777237B (en) Oxazolidinedione derivatives of vinca alkaloids
GB1521053A (en) Derivatives of vinblastine vincristine and leurosidine
HK15383A (en) Stable solutions of ergot alkaloids
GB1485738A (en) Ergot alkaloids
JPS5283900A (en) Novel acidic and ester derivatives of vinblastine vincrystine and roylocidine
GR59327B (en) Preparation process of alkaloid derivatives
AU482431B2 (en) Novel amide derivatives of vlb and leurocristine
AU2103877A (en) Ergot alkaloid derivatives
GB1557331A (en) Pharmaceutical compositions containing an ergot alkaloid and heparing
AU2857277A (en) 6' Desoxo derivatives of ergot peptide alkaloid
ZA773346B (en) Novel derivatives of vincamine and apovincamine and related preparation process
IL52632A0 (en) Novel alkaloid derivatives and their preparation
JPS5283840A (en) Acylated derivatives of pyrazofline

Legal Events

Date Code Title Description
RH Patent void