IL51648A - 4-amino chromanol derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

4-amino chromanol derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL51648A
IL51648A IL51648A IL5164877A IL51648A IL 51648 A IL51648 A IL 51648A IL 51648 A IL51648 A IL 51648A IL 5164877 A IL5164877 A IL 5164877A IL 51648 A IL51648 A IL 51648A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
chromanol derivatives
amino
Prior art date
Application number
IL51648A
Other languages
English (en)
Other versions
IL51648A0 (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB13536/76A external-priority patent/GB1511187A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IL51648A0 publication Critical patent/IL51648A0/xx
Publication of IL51648A publication Critical patent/IL51648A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
IL51648A 1976-04-02 1977-03-11 4-amino chromanol derivatives,their preparation and pharmaceutical compositions containing them IL51648A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB13536/76A GB1511187A (en) 1976-04-02 1976-04-02 Chromans
GB3317876 1976-08-10

Publications (2)

Publication Number Publication Date
IL51648A0 IL51648A0 (en) 1977-05-31
IL51648A true IL51648A (en) 1982-08-31

Family

ID=26249838

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51648A IL51648A (en) 1976-04-02 1977-03-11 4-amino chromanol derivatives,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4251537A (xx)
JP (1) JPS52122372A (xx)
AU (1) AU503934B2 (xx)
CA (1) CA1119180A (xx)
CH (1) CH632262A5 (xx)
DE (2) DE2713670A1 (xx)
DK (1) DK147777A (xx)
ES (1) ES457417A1 (xx)
FR (1) FR2346346A1 (xx)
IE (1) IE44977B1 (xx)
IL (1) IL51648A (xx)
NL (2) NL7703440A (xx)
NZ (1) NZ183551A (xx)
SE (1) SE7703715L (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028064B1 (en) * 1979-09-28 1983-07-20 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
DE3064285D1 (en) 1979-09-28 1983-08-25 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
EP0046652B1 (en) * 1980-08-21 1985-05-22 Beecham Group Plc Chromanol derivatives, their production and pharmaceutical compositions containing them
US4447622A (en) * 1981-09-22 1984-05-08 Council Of Scientific And Industrial Research Rafi Marg Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
US4404207A (en) * 1981-11-06 1983-09-13 Riker Laboratories, Inc. Antimicrobial 8-substituted benzo [IJ]quinolizines
DE3364145D1 (de) * 1982-04-08 1986-07-24 Beecham Group Plc Antihypertensive benzopyranols
DE3368057D1 (en) * 1982-05-21 1987-01-15 Beecham Group Plc Pharmaceutically active aminobenzopyrans
GB8308063D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
EP0139992B1 (en) * 1983-09-01 1988-12-28 Beecham Group Plc Chromanol derivatives
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
IL88035A0 (en) * 1987-10-27 1989-06-30 American Home Prod Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
DE3827532A1 (de) * 1988-08-13 1990-03-01 Hoechst Ag 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
US4997846A (en) * 1988-12-09 1991-03-05 Researche Syntex France, S.A. Novel benzopyranylpyrrolinone derivatives
US4908378A (en) * 1989-04-12 1990-03-13 American Home Products Corporation Benzopyran derivatives and antihypertensive use thereof
DE3923839A1 (de) * 1989-07-19 1991-01-31 Beiersdorf Ag Benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1495526A (en) * 1974-05-31 1977-12-21 Beecham Group Ltd Chroman derivatives
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.

Also Published As

Publication number Publication date
DE2713670A1 (de) 1977-10-06
IL51648A0 (en) 1977-05-31
AU503934B2 (en) 1979-09-27
CH632262A5 (de) 1982-09-30
DE2760316C3 (de) 1993-12-23
DE2760316C2 (xx) 1993-12-23
US4251537A (en) 1981-02-17
FR2346346B1 (xx) 1980-03-07
JPS6112910B2 (xx) 1986-04-10
JPS52122372A (en) 1977-10-14
IE44977L (en) 1977-10-02
NZ183551A (en) 1978-09-20
FR2346346A1 (fr) 1977-10-28
AU2387577A (en) 1978-10-12
CA1119180A (en) 1982-03-02
NL7703440A (nl) 1977-10-04
IE44977B1 (en) 1982-06-02
SE7703715L (sv) 1977-10-03
NL8402722A (nl) 1984-12-03
DK147777A (da) 1977-10-03
ES457417A1 (es) 1978-07-16

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