IL51574A - Process for preparing racemic and optically active 1-tert-butylamino-3-(2,5-dichloro-phenoxy)-2propanol - Google Patents

Process for preparing racemic and optically active 1-tert-butylamino-3-(2,5-dichloro-phenoxy)-2propanol

Info

Publication number
IL51574A
IL51574A IL51574A IL5157477A IL51574A IL 51574 A IL51574 A IL 51574A IL 51574 A IL51574 A IL 51574A IL 5157477 A IL5157477 A IL 5157477A IL 51574 A IL51574 A IL 51574A
Authority
IL
Israel
Prior art keywords
2propanol
butylamino
dichloro
phenoxy
tert
Prior art date
Application number
IL51574A
Other languages
English (en)
Other versions
IL51574A0 (en
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL51574A0 publication Critical patent/IL51574A0/xx
Publication of IL51574A publication Critical patent/IL51574A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL51574A 1976-03-02 1977-03-01 Process for preparing racemic and optically active 1-tert-butylamino-3-(2,5-dichloro-phenoxy)-2propanol IL51574A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76GO00001331A HU172137B (hu) 1976-03-02 1976-03-02 Sposob poluchenija zamehhjonnykh proizvodnykh fenoksi-propanolamina

Publications (2)

Publication Number Publication Date
IL51574A0 IL51574A0 (en) 1977-05-31
IL51574A true IL51574A (en) 1980-01-31

Family

ID=10996805

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51574A IL51574A (en) 1976-03-02 1977-03-01 Process for preparing racemic and optically active 1-tert-butylamino-3-(2,5-dichloro-phenoxy)-2propanol

Country Status (25)

Country Link
US (1) US4310549A (no)
JP (1) JPS5923299B2 (no)
AT (1) AT348507B (no)
AU (1) AU508766B2 (no)
BE (1) BE851938A (no)
CA (1) CA1091254A (no)
CH (1) CH627732A5 (no)
CS (1) CS190340B2 (no)
DD (1) DD128610A5 (no)
DE (1) DE2709109C3 (no)
DK (1) DK143554C (no)
FI (1) FI65231C (no)
FR (1) FR2342956A1 (no)
GB (1) GB1573191A (no)
HU (1) HU172137B (no)
IL (1) IL51574A (no)
IN (1) IN144243B (no)
KE (1) KE3340A (no)
MY (1) MY8500104A (no)
NL (1) NL7702170A (no)
NO (1) NO141989C (no)
PL (1) PL103734B1 (no)
SE (1) SE440647B (no)
SU (1) SU648080A3 (no)
YU (1) YU40813B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP20084406B (en) * 2003-05-30 2008-06-25 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as hmg-co inhibitors
AU2006313430B2 (en) * 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
CN101494980A (zh) * 2006-07-14 2009-07-29 兰贝克赛实验室有限公司 HMG-CoA还原酶抑制剂的多晶型形式及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH569692A5 (no) 1971-03-17 1975-11-28 Richter Gedeon Vegyeszet
US4067904A (en) * 1975-12-19 1978-01-10 Mead Johnson & Company Alkylsulfonylphenoxypropanolamine derivatives

Also Published As

Publication number Publication date
DK143554C (da) 1982-03-08
IL51574A0 (en) 1977-05-31
SE440647B (sv) 1985-08-12
ATA134177A (de) 1978-07-15
FI65231C (fi) 1984-04-10
AU508766B2 (en) 1980-04-03
NL7702170A (nl) 1977-09-06
FI770651A (no) 1977-09-03
SE7702251L (sv) 1977-09-03
NO141989B (no) 1980-03-03
CA1091254A (en) 1980-12-09
MY8500104A (en) 1985-12-31
CS190340B2 (en) 1979-05-31
FR2342956B1 (no) 1982-11-26
GB1573191A (en) 1980-08-20
FI65231B (fi) 1983-12-30
NO770688L (no) 1977-09-05
FR2342956A1 (fr) 1977-09-30
CH627732A5 (de) 1982-01-29
YU40813B (en) 1986-06-30
JPS52122328A (en) 1977-10-14
IN144243B (no) 1978-04-15
BE851938A (fr) 1977-09-01
NO141989C (no) 1980-06-11
DE2709109C3 (de) 1980-09-18
KE3340A (en) 1983-11-25
DD128610A5 (de) 1977-11-30
DK143554B (da) 1981-09-07
DE2709109B2 (de) 1980-01-17
HU172137B (hu) 1978-06-28
SU648080A3 (ru) 1979-02-15
JPS5923299B2 (ja) 1984-06-01
AT348507B (de) 1979-02-26
US4310549A (en) 1982-01-12
YU54977A (en) 1982-10-31
PL103734B1 (pl) 1979-07-31
DK88577A (da) 1977-09-03
AU2279577A (en) 1978-09-07
DE2709109A1 (de) 1977-09-15

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IL51574A (en) Process for preparing racemic and optically active 1-tert-butylamino-3-(2,5-dichloro-phenoxy)-2propanol
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