ATA134177A - Verfahren zur herstellung von racemischem und von optisch aktivem 1-tert. butylamino-3- (2',5'-dichlorphenoxy)-2-propanol und dessen saeureadditionssalzen - Google Patents
Verfahren zur herstellung von racemischem und von optisch aktivem 1-tert. butylamino-3- (2',5'-dichlorphenoxy)-2-propanol und dessen saeureadditionssalzenInfo
- Publication number
- ATA134177A ATA134177A AT134177A AT134177A ATA134177A AT A134177 A ATA134177 A AT A134177A AT 134177 A AT134177 A AT 134177A AT 134177 A AT134177 A AT 134177A AT A134177 A ATA134177 A AT A134177A
- Authority
- AT
- Austria
- Prior art keywords
- dichlorophenoxy
- butylamino
- propanol
- tert
- acid addition
- Prior art date
Links
- RCFWWYVWLFLGRO-UHFFFAOYSA-N 1-(butylamino)-3-(2,5-dichlorophenoxy)propan-2-ol Chemical compound CCCCNCC(O)COC1=CC(Cl)=CC=C1Cl RCFWWYVWLFLGRO-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU76GO00001331A HU172137B (hu) | 1976-03-02 | 1976-03-02 | Sposob poluchenija zamehhjonnykh proizvodnykh fenoksi-propanolamina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA134177A true ATA134177A (de) | 1978-07-15 |
| AT348507B AT348507B (de) | 1979-02-26 |
Family
ID=10996805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT134177A AT348507B (de) | 1976-03-02 | 1977-02-28 | Verfahren zur herstellung von racemischem und von optisch aktivem 1-tert. butylamino-3- (2',5'-dichlorphenoxy)-2-propanol und dessen saeureadditionssalzen |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4310549A (de) |
| JP (1) | JPS5923299B2 (de) |
| AT (1) | AT348507B (de) |
| AU (1) | AU508766B2 (de) |
| BE (1) | BE851938A (de) |
| CA (1) | CA1091254A (de) |
| CH (1) | CH627732A5 (de) |
| CS (1) | CS190340B2 (de) |
| DD (1) | DD128610A5 (de) |
| DE (1) | DE2709109C3 (de) |
| DK (1) | DK143554C (de) |
| FI (1) | FI65231C (de) |
| FR (1) | FR2342956A1 (de) |
| GB (1) | GB1573191A (de) |
| HU (1) | HU172137B (de) |
| IL (1) | IL51574A (de) |
| IN (1) | IN144243B (de) |
| KE (1) | KE3340A (de) |
| MY (1) | MY8500104A (de) |
| NL (1) | NL7702170A (de) |
| NO (1) | NO141989C (de) |
| PL (1) | PL103734B1 (de) |
| SE (1) | SE440647B (de) |
| SU (1) | SU648080A3 (de) |
| YU (1) | YU40813B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4901474B2 (ja) * | 2003-05-30 | 2012-03-21 | ランバクシー ラボラトリーズ リミテッド | 置換ピロール誘導体 |
| KR101329112B1 (ko) * | 2005-11-08 | 2013-11-14 | 랜박시 래보러터리스 리미티드 | (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법 |
| US20070238716A1 (en) * | 2006-03-14 | 2007-10-11 | Murthy Ayanampudi S R | Statin stabilizing dosage formulations |
| EP2049102A4 (de) * | 2006-07-14 | 2010-12-22 | Ranbaxy Lab Ltd | Polymorphe formen eines hmg-coa-reduktasehemmers und verwendung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH569692A5 (de) | 1971-03-17 | 1975-11-28 | Richter Gedeon Vegyeszet | |
| US4067904A (en) * | 1975-12-19 | 1978-01-10 | Mead Johnson & Company | Alkylsulfonylphenoxypropanolamine derivatives |
-
1976
- 1976-03-02 HU HU76GO00001331A patent/HU172137B/hu not_active IP Right Cessation
-
1977
- 1977-02-25 CH CH235877A patent/CH627732A5/de unknown
- 1977-02-28 AT AT134177A patent/AT348507B/de not_active IP Right Cessation
- 1977-03-01 AU AU22795/77A patent/AU508766B2/en not_active Expired
- 1977-03-01 GB GB8593/77A patent/GB1573191A/en not_active Expired
- 1977-03-01 BE BE1007979A patent/BE851938A/xx not_active IP Right Cessation
- 1977-03-01 SE SE7702251A patent/SE440647B/xx not_active IP Right Cessation
- 1977-03-01 FI FI770651A patent/FI65231C/fi not_active IP Right Cessation
- 1977-03-01 PL PL1977196357A patent/PL103734B1/pl unknown
- 1977-03-01 DK DK88577A patent/DK143554C/da not_active IP Right Cessation
- 1977-03-01 IL IL51574A patent/IL51574A/xx unknown
- 1977-03-01 NL NL7702170A patent/NL7702170A/xx not_active Application Discontinuation
- 1977-03-01 DD DD7700197617A patent/DD128610A5/de unknown
- 1977-03-01 IN IN292/CAL/77A patent/IN144243B/en unknown
- 1977-03-01 CA CA272,912A patent/CA1091254A/en not_active Expired
- 1977-03-01 SU SU772457128A patent/SU648080A3/ru active
- 1977-03-01 CS CS771363A patent/CS190340B2/cs unknown
- 1977-03-01 NO NO770688A patent/NO141989C/no unknown
- 1977-03-01 YU YU549/77A patent/YU40813B/xx unknown
- 1977-03-01 FR FR7705898A patent/FR2342956A1/fr active Granted
- 1977-03-02 DE DE2709109A patent/DE2709109C3/de not_active Expired
- 1977-03-02 JP JP52021640A patent/JPS5923299B2/ja not_active Expired
-
1979
- 1979-09-04 US US06/072,295 patent/US4310549A/en not_active Expired - Lifetime
-
1983
- 1983-10-24 KE KE3340A patent/KE3340A/xx unknown
-
1985
- 1985-12-30 MY MY104/85A patent/MY8500104A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |