IL51316A - 1-diphenylmethyl-3-hydroxybenzyl piperazine derivatives,method for their preparation and pharmaceutical compositionscontaining them - Google Patents

1-diphenylmethyl-3-hydroxybenzyl piperazine derivatives,method for their preparation and pharmaceutical compositionscontaining them

Info

Publication number
IL51316A
IL51316A IL51316A IL5131677A IL51316A IL 51316 A IL51316 A IL 51316A IL 51316 A IL51316 A IL 51316A IL 5131677 A IL5131677 A IL 5131677A IL 51316 A IL51316 A IL 51316A
Authority
IL
Israel
Prior art keywords
diphenylmethyl
hydroxybenzyl
preparation
piperazine derivatives
compositionscontaining
Prior art date
Application number
IL51316A
Other languages
English (en)
Other versions
IL51316A0 (en
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of IL51316A0 publication Critical patent/IL51316A0/xx
Publication of IL51316A publication Critical patent/IL51316A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL51316A 1976-02-07 1977-01-24 1-diphenylmethyl-3-hydroxybenzyl piperazine derivatives,method for their preparation and pharmaceutical compositionscontaining them IL51316A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762604845 DE2604845A1 (de) 1976-02-07 1976-02-07 Neue piperazinderivate

Publications (2)

Publication Number Publication Date
IL51316A0 IL51316A0 (en) 1977-03-31
IL51316A true IL51316A (en) 1980-12-31

Family

ID=5969327

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51316A IL51316A (en) 1976-02-07 1977-01-24 1-diphenylmethyl-3-hydroxybenzyl piperazine derivatives,method for their preparation and pharmaceutical compositionscontaining them

Country Status (25)

Country Link
US (1) US4079137A (pt)
JP (1) JPS52105186A (pt)
AT (1) AT355578B (pt)
AU (1) AU504526B2 (pt)
BE (1) BE850492A (pt)
CA (1) CA1094560A (pt)
CH (1) CH631448A5 (pt)
CS (1) CS201544B2 (pt)
DD (1) DD128133A5 (pt)
DE (1) DE2604845A1 (pt)
DK (1) DK138891C (pt)
ES (1) ES455691A1 (pt)
FI (1) FI63226C (pt)
FR (1) FR2340311A1 (pt)
GB (1) GB1550545A (pt)
HU (1) HU173483B (pt)
IE (1) IE44339B1 (pt)
IL (1) IL51316A (pt)
LU (1) LU76706A1 (pt)
NL (1) NL7700841A (pt)
NO (1) NO142625C (pt)
PL (1) PL105526B1 (pt)
PT (1) PT66154B (pt)
SE (1) SE7701187L (pt)
ZA (1) ZA77248B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341698A (en) * 1979-06-21 1982-07-27 Richardson-Merrell Inc. Enkaphalin derivatives
US4483988A (en) * 1980-03-14 1984-11-20 Richardson Merrell Inc. Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
CA2588685A1 (en) * 2004-12-06 2006-06-15 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as cancer vaccine adjuvants
US20080300166A1 (en) * 2007-06-01 2008-12-04 Sciclone Pharmaceuticals, Inc. Treatment of Melanoma with Alpha Thymosin Peptides
WO2009075813A1 (en) * 2007-12-12 2009-06-18 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with antibodies against cytotoxic t lymphocyte-associated antigen 4 (ctla4)
EP2240194A4 (en) * 2007-12-13 2011-12-21 Sciclone Pharmaceuticals Inc TREATMENT OF MELANOMA WITH ALPHA THYMOSIN PEPTIDES IN COMBINATION WITH A KINASE INHIBITOR
WO2009079338A1 (en) * 2007-12-14 2009-06-25 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa)
US8829173B2 (en) 2008-09-26 2014-09-09 Tocagen Inc. Recombinant vectors
WO2010129947A2 (en) * 2009-05-08 2010-11-11 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as vaccine enhancers
TWI749433B (zh) 2014-10-21 2021-12-11 開曼群島商賽生製藥國際有限公司 用免疫刺激物治療癌症

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472856A (en) * 1967-05-29 1969-10-14 Sterling Drug Inc 1-((thianaphthenyl)-lower-alkyl)-4-substituted-piperazines
DE2438725A1 (de) * 1974-08-12 1976-02-26 Knoll Ag Piperazinderivate
US4031216A (en) * 1974-08-12 1977-06-21 Knoll A.G. Chemische Fabriken 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines

Also Published As

Publication number Publication date
FR2340311A1 (fr) 1977-09-02
CH631448A5 (de) 1982-08-13
HU173483B (hu) 1979-05-28
CS201544B2 (en) 1980-11-28
IE44339B1 (en) 1981-10-21
NO770374L (no) 1977-08-09
IL51316A0 (en) 1977-03-31
ZA77248B (en) 1977-11-30
US4079137A (en) 1978-03-14
FI63226B (fi) 1983-01-31
FR2340311B1 (pt) 1980-02-08
LU76706A1 (pt) 1977-06-28
NL7700841A (nl) 1977-08-09
JPS52105186A (en) 1977-09-03
AU2195277A (en) 1978-08-10
SE7701187L (sv) 1977-08-08
AU504526B2 (en) 1979-10-18
GB1550545A (en) 1979-08-15
DK138891B (da) 1978-11-13
FI770398A (pt) 1977-08-08
PT66154B (fr) 1978-07-07
FI63226C (fi) 1983-05-10
NO142625C (no) 1980-09-17
DK49077A (da) 1977-08-08
BE850492A (fr) 1977-07-18
DD128133A5 (de) 1977-11-02
PT66154A (fr) 1977-03-01
DE2604845A1 (de) 1977-08-18
IE44339L (en) 1977-08-07
AT355578B (de) 1980-03-10
DK138891C (da) 1979-04-23
PL105526B1 (pl) 1979-10-31
CA1094560A (en) 1981-01-27
NO142625B (no) 1980-06-09
ATA68177A (de) 1979-08-15
ES455691A1 (es) 1978-01-01

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