IL51024A - Substituted n-substituted imidazo(1,2-a)pyridine 2(or 3)-yl-alkanamides and carbamates and their preparation - Google Patents
Substituted n-substituted imidazo(1,2-a)pyridine 2(or 3)-yl-alkanamides and carbamates and their preparationInfo
- Publication number
- IL51024A IL51024A IL51024A IL5102476A IL51024A IL 51024 A IL51024 A IL 51024A IL 51024 A IL51024 A IL 51024A IL 5102476 A IL5102476 A IL 5102476A IL 51024 A IL51024 A IL 51024A
- Authority
- IL
- Israel
- Prior art keywords
- substituted
- alkanamides
- carbamates
- pyridine
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/86—Hydrazides; Thio or imino analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63903475A | 1975-12-09 | 1975-12-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL51024A0 IL51024A0 (en) | 1977-01-31 |
IL51024A true IL51024A (en) | 1981-12-31 |
Family
ID=24562456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL51024A IL51024A (en) | 1975-12-09 | 1976-11-29 | Substituted n-substituted imidazo(1,2-a)pyridine 2(or 3)-yl-alkanamides and carbamates and their preparation |
Country Status (25)
Country | Link |
---|---|
US (1) | US4096264A (fr) |
JP (1) | JPS5273896A (fr) |
AR (1) | AR222960A1 (fr) |
AT (1) | AT361475B (fr) |
AU (1) | AU505045B2 (fr) |
BE (1) | BE849123A (fr) |
CA (1) | CA1084930A (fr) |
CH (1) | CH626362A5 (fr) |
DE (1) | DE2655681A1 (fr) |
DK (1) | DK529276A (fr) |
ES (1) | ES453947A1 (fr) |
FI (1) | FI763343A (fr) |
FR (1) | FR2334357A1 (fr) |
GB (1) | GB1524589A (fr) |
GR (1) | GR62009B (fr) |
IL (1) | IL51024A (fr) |
NL (1) | NL7613160A (fr) |
NO (1) | NO764025L (fr) |
NZ (1) | NZ182756A (fr) |
OA (1) | OA05506A (fr) |
PH (1) | PH12259A (fr) |
PL (1) | PL103751B1 (fr) |
PT (1) | PT65915B (fr) |
SE (1) | SE430504B (fr) |
ZA (1) | ZA767331B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105767A (en) * | 1977-03-28 | 1978-08-08 | Merck & Co., Inc. | Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group |
US4154835A (en) * | 1977-10-12 | 1979-05-15 | Merck & Co., Inc. | Anthelmintic imidazo [1,2-a] pyridines |
US4250174A (en) * | 1979-05-02 | 1981-02-10 | Merck & Co., Inc. | 3-Substituted imidazo [1,2-A] pyridines |
US4221796A (en) * | 1979-09-19 | 1980-09-09 | E. R. Squibb & Sons, Inc. | Substituted imidazolo-pyridines and method |
ZA81219B (en) * | 1980-01-23 | 1982-01-27 | Schering Corp | Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them |
US4507481A (en) * | 1983-07-29 | 1985-03-26 | Pennwalt Corporation | Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines |
IT1173196B (it) * | 1984-02-02 | 1987-06-18 | Bellon Roger Schoum Rbs Pharma | Composti imidazopiridinici farmacologicamente attivi |
US5214138A (en) * | 1989-12-20 | 1993-05-25 | Case Western Reserve University | Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same |
CA2048110C (fr) * | 1990-07-30 | 2002-06-25 | Muneo Takatani | Derives d'imidazopyridine et leur utilisation |
EP1077701A4 (fr) * | 1998-05-20 | 2002-03-20 | Lilly Co Eli | Composes anti-viraux |
US6358971B1 (en) | 1998-05-20 | 2002-03-19 | Eli Lilly And Company | Anti-viral compounds |
DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
DK1737459T3 (da) * | 2004-03-19 | 2009-10-26 | Warner Lambert Co | Imidazopyridin og imidazopyrimidinderivater som antibakterielle midler |
DE602005020313D1 (de) * | 2004-08-12 | 2010-05-12 | Amgen Inc | Bisaryl-sulfonamide |
JP5352476B2 (ja) * | 2007-06-05 | 2013-11-27 | 武田薬品工業株式会社 | キナーゼ阻害剤としての二環式複素環化合物 |
US8431608B2 (en) | 2007-08-17 | 2013-04-30 | Icagen Inc. | Heterocycles as potassium channel modulators |
EP2178373B1 (fr) * | 2007-08-17 | 2013-01-23 | Icagen, Inc. | Hétérocycles en tant que modulateurs de canal potassique |
EP2181987B9 (fr) * | 2007-08-23 | 2014-09-03 | Takeda Pharmaceutical Company Limited | 2-Carbonylaminobenzothiazoles et leur utilisation dans la prévention ou le traitement du cancer |
JP5350247B2 (ja) * | 2007-08-29 | 2013-11-27 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
JPWO2009128520A1 (ja) | 2008-04-18 | 2011-08-04 | 塩野義製薬株式会社 | Pi3k阻害活性を有する複素環化合物 |
WO2009136663A1 (fr) * | 2008-05-08 | 2009-11-12 | Takeda Pharmaceutical Company Limited | Dérivés hétérocycliques fusionnés et leur utilisation |
EP2399921B1 (fr) * | 2008-12-01 | 2015-08-12 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique et applications |
JO3101B1 (ar) | 2008-12-02 | 2017-09-20 | Takeda Pharmaceuticals Co | مشتقات بنزوثيازول كعوامل مضادة للسرطان |
EP2467142B1 (fr) | 2009-08-17 | 2016-09-21 | Memorial Sloan-Kettering Cancer Center | Dérivés 2-(pyrimidin-5-yl)-thiopyrimidine en tant que modulateurs Hsp70 and Hsc70 pour le traitement de maladies proliferatives |
ES2774975T3 (es) | 2014-05-13 | 2020-07-23 | Memorial Sloan Kettering Cancer Center | Moduladores de hsp70 y métodos para fabricar y utilizar el mismo |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3701780A (en) * | 1970-09-18 | 1972-10-31 | Merck & Co Inc | Imidazo(1,2-a)pyridines |
JPS5124517B1 (fr) * | 1971-03-15 | 1976-07-24 |
-
1976
- 1976-08-26 US US05/718,652 patent/US4096264A/en not_active Expired - Lifetime
- 1976-11-22 FI FI763343A patent/FI763343A/fi not_active Application Discontinuation
- 1976-11-24 DK DK529276A patent/DK529276A/da not_active Application Discontinuation
- 1976-11-24 SE SE7613128A patent/SE430504B/xx unknown
- 1976-11-25 NL NL7613160A patent/NL7613160A/xx not_active Application Discontinuation
- 1976-11-25 NO NO764025A patent/NO764025L/no unknown
- 1976-11-29 IL IL51024A patent/IL51024A/xx unknown
- 1976-11-29 NZ NZ182756A patent/NZ182756A/xx unknown
- 1976-11-30 AU AU20102/76A patent/AU505045B2/en not_active Expired
- 1976-12-01 AR AR265695A patent/AR222960A1/es active
- 1976-12-01 CH CH1513176A patent/CH626362A5/de not_active IP Right Cessation
- 1976-12-02 PT PT65915A patent/PT65915B/pt unknown
- 1976-12-03 ES ES453947A patent/ES453947A1/es not_active Expired
- 1976-12-06 AT AT901876A patent/AT361475B/de not_active IP Right Cessation
- 1976-12-07 PH PH19211A patent/PH12259A/en unknown
- 1976-12-07 GB GB51010/76A patent/GB1524589A/en not_active Expired
- 1976-12-07 GR GR52346A patent/GR62009B/el unknown
- 1976-12-07 CA CA267,311A patent/CA1084930A/fr not_active Expired
- 1976-12-07 BE BE173014A patent/BE849123A/fr not_active IP Right Cessation
- 1976-12-07 FR FR7636779A patent/FR2334357A1/fr active Granted
- 1976-12-08 DE DE19762655681 patent/DE2655681A1/de not_active Ceased
- 1976-12-08 ZA ZA00767331A patent/ZA767331B/xx unknown
- 1976-12-08 PL PL1976194238A patent/PL103751B1/pl unknown
- 1976-12-09 OA OA56008A patent/OA05506A/fr unknown
- 1976-12-09 JP JP51147227A patent/JPS5273896A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
NO764025L (fr) | 1977-06-10 |
PH12259A (en) | 1978-12-12 |
NL7613160A (nl) | 1977-06-13 |
FR2334357B1 (fr) | 1982-10-15 |
JPS6126545B2 (fr) | 1986-06-20 |
PT65915B (en) | 1978-11-07 |
SE430504B (sv) | 1983-11-21 |
GB1524589A (en) | 1978-09-13 |
CA1084930A (fr) | 1980-09-02 |
IL51024A0 (en) | 1977-01-31 |
ATA901876A (de) | 1980-08-15 |
PL103751B1 (pl) | 1979-07-31 |
FR2334357A1 (fr) | 1977-07-08 |
PT65915A (en) | 1977-01-01 |
AR222960A1 (es) | 1981-07-15 |
AT361475B (de) | 1981-03-10 |
GR62009B (en) | 1979-02-15 |
SE7613128L (sv) | 1977-06-10 |
OA05506A (fr) | 1981-04-30 |
DE2655681A1 (de) | 1977-06-16 |
CH626362A5 (fr) | 1981-11-13 |
FI763343A (fr) | 1977-06-10 |
AU505045B2 (en) | 1979-11-08 |
NZ182756A (en) | 1979-11-01 |
DK529276A (da) | 1977-06-10 |
BE849123A (fr) | 1977-06-07 |
US4096264A (en) | 1978-06-20 |
ZA767331B (en) | 1978-07-26 |
AU2010276A (en) | 1978-06-08 |
ES453947A1 (es) | 1978-03-01 |
JPS5273896A (en) | 1977-06-21 |
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