IL50657A - 11-deoxy-16-aryl- -tetranor-prosta-cis-5-ene-13-yneoic acid derivatives and their preparation - Google Patents

11-deoxy-16-aryl- -tetranor-prosta-cis-5-ene-13-yneoic acid derivatives and their preparation

Info

Publication number
IL50657A
IL50657A IL50657A IL5065776A IL50657A IL 50657 A IL50657 A IL 50657A IL 50657 A IL50657 A IL 50657A IL 5065776 A IL5065776 A IL 5065776A IL 50657 A IL50657 A IL 50657A
Authority
IL
Israel
Prior art keywords
yneoic
prosta
tetranor
deoxy
ene
Prior art date
Application number
IL50657A
Other languages
English (en)
Other versions
IL50657A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL50657A0 publication Critical patent/IL50657A0/xx
Publication of IL50657A publication Critical patent/IL50657A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL50657A 1975-10-21 1976-10-11 11-deoxy-16-aryl- -tetranor-prosta-cis-5-ene-13-yneoic acid derivatives and their preparation IL50657A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/624,486 US3984400A (en) 1975-10-21 1975-10-21 11-Desoxy-16-aryl-ω-tetranorprostaglandins

Publications (2)

Publication Number Publication Date
IL50657A0 IL50657A0 (en) 1976-12-31
IL50657A true IL50657A (en) 1980-05-30

Family

ID=24502191

Family Applications (1)

Application Number Title Priority Date Filing Date
IL50657A IL50657A (en) 1975-10-21 1976-10-11 11-deoxy-16-aryl- -tetranor-prosta-cis-5-ene-13-yneoic acid derivatives and their preparation

Country Status (30)

Country Link
US (1) US3984400A (da)
JP (2) JPS5251353A (da)
AR (1) AR213831A1 (da)
AT (1) AT360673B (da)
BE (1) BE847447A (da)
BG (1) BG31070A3 (da)
CA (1) CA1092103A (da)
CH (1) CH619930A5 (da)
CS (2) CS191321B2 (da)
DD (1) DD128590A5 (da)
DE (1) DE2646878A1 (da)
DK (1) DK472976A (da)
ES (1) ES452538A1 (da)
FI (1) FI762990A (da)
GB (1) GB1520958A (da)
GR (1) GR63621B (da)
HU (1) HU175022B (da)
IE (1) IE44016B1 (da)
IL (1) IL50657A (da)
LU (1) LU76045A1 (da)
NL (1) NL163780C (da)
NO (1) NO763451L (da)
NZ (1) NZ182297A (da)
PH (1) PH11472A (da)
PL (1) PL112539B1 (da)
PT (1) PT65727B (da)
RO (1) RO71900A (da)
SE (1) SE7610995L (da)
SU (2) SU727139A3 (da)
ZA (1) ZA766204B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4365077A (en) * 1975-06-23 1982-12-21 Pfizer Inc. 11-Desoxy-16-aryloxy-ω-tetranorprostaglandins
ZA77160B (en) * 1976-02-13 1977-11-30 Upjohn Co Prostaglandin analogs
US4058564A (en) * 1976-07-26 1977-11-15 The Upjohn Company Aliphatic 2-decarboxy-2-hydroxymethyl-13,14-didehydro-PG compounds
US4140721A (en) * 1976-07-26 1979-02-20 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-13,14-didehydro-17-phenyl-PGA, PGD and PGE compounds
US4177346A (en) * 1976-08-06 1979-12-04 Pfizer Inc. 1,5-Disubstituted-2-pyrrolidones
JPS6210843Y2 (da) * 1981-01-23 1987-03-14
JPS59190734U (ja) * 1983-06-06 1984-12-18 庄田商事株式会社 薄板用連続送り装置
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
US4883614A (en) * 1984-07-27 1989-11-28 Hoffman-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4780251A (en) * 1984-07-27 1988-10-25 Hoffman-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
EP2741738A1 (en) 2011-08-12 2014-06-18 Ascendis Pharma A/S Sustained release composition of prostacyclin
US10544915B2 (en) * 2017-04-27 2020-01-28 Valeo North America, Inc. Vehicle lamp assembly having an improved heat sink with light shield

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3840573A (en) * 1970-12-21 1974-10-08 Searle & Co 2-(3-hydroxy-3-optionally alkylated-1-alkynyl)-3-hydroxy-5-oxygenated cyclopent-1-enealkanoic acids,optical isomers thereof and esters corresponding
US3932389A (en) * 1974-12-11 1976-01-13 Pfizer Inc. 2-Descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-.omega.-pentanorprostaglandins

Also Published As

Publication number Publication date
IL50657A0 (en) 1976-12-31
PH11472A (en) 1978-02-01
IE44016B1 (en) 1981-07-29
CS191343B2 (en) 1979-06-29
LU76045A1 (da) 1977-05-31
PT65727A (en) 1976-11-01
US3984400A (en) 1976-10-05
ZA766204B (en) 1977-09-28
JPS5490168A (en) 1979-07-17
BG31070A3 (en) 1981-10-15
CH619930A5 (da) 1980-10-31
PT65727B (en) 1978-04-18
DD128590A5 (de) 1977-11-30
NL163780C (nl) 1980-10-15
NL7611660A (nl) 1977-04-25
JPS5251353A (en) 1977-04-25
HU175022B (hu) 1980-04-28
DK472976A (da) 1977-04-22
FI762990A (da) 1977-04-22
DE2646878A1 (de) 1977-05-05
GB1520958A (en) 1978-08-09
NO763451L (da) 1977-04-22
AU1873776A (en) 1978-02-16
CS191321B2 (en) 1979-06-29
IE44016L (en) 1977-04-21
SE7610995L (sv) 1977-04-22
RO71900A (ro) 1981-05-30
JPS5531153B2 (da) 1980-08-15
AR213831A1 (es) 1979-03-30
PL193183A1 (pl) 1978-03-28
BE847447A (fr) 1977-04-20
PL112539B1 (en) 1980-10-31
GR63621B (en) 1979-11-27
ES452538A1 (es) 1977-11-01
CA1092103A (en) 1980-12-23
AT360673B (de) 1981-01-26
SU900806A3 (ru) 1982-01-23
ATA785876A (de) 1980-06-15
NL163780B (nl) 1980-05-16
NZ182297A (en) 1978-09-25
SU727139A3 (ru) 1980-04-05

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