IL49503A - Process for the preparation of 6-phenyl-4h-s-triazolo(4,3-a)(1,4)-benzodiazepines and intermediate 2-(3-(phthalimidomethyl)-4h-1,2,4-triazol-4-yl)benzophenones - Google Patents

Process for the preparation of 6-phenyl-4h-s-triazolo(4,3-a)(1,4)-benzodiazepines and intermediate 2-(3-(phthalimidomethyl)-4h-1,2,4-triazol-4-yl)benzophenones

Info

Publication number
IL49503A
IL49503A IL49503A IL4950374A IL49503A IL 49503 A IL49503 A IL 49503A IL 49503 A IL49503 A IL 49503A IL 4950374 A IL4950374 A IL 4950374A IL 49503 A IL49503 A IL 49503A
Authority
IL
Israel
Prior art keywords
compound
alkyl
triazol
chloro
jbenzophenone
Prior art date
Application number
IL49503A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL49503A publication Critical patent/IL49503A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL49503A 1973-02-14 1974-01-24 Process for the preparation of 6-phenyl-4h-s-triazolo(4,3-a)(1,4)-benzodiazepines and intermediate 2-(3-(phthalimidomethyl)-4h-1,2,4-triazol-4-yl)benzophenones IL49503A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33237773A 1973-02-14 1973-02-14

Publications (1)

Publication Number Publication Date
IL49503A true IL49503A (en) 1977-05-31

Family

ID=23297958

Family Applications (3)

Application Number Title Priority Date Filing Date
IL49503A IL49503A (en) 1973-02-14 1974-01-24 Process for the preparation of 6-phenyl-4h-s-triazolo(4,3-a)(1,4)-benzodiazepines and intermediate 2-(3-(phthalimidomethyl)-4h-1,2,4-triazol-4-yl)benzophenones
IL44068A IL44068A (en) 1973-02-14 1974-01-24 Process for the preparation of 6-phenyl-4h-s-triazolo(4,3a)(1,4)benzodiazepines and intermediate 2(2-(methanesulfonyl)methyl)-4h-1,2,4-triazol-4yl)benzophenones
IL49503A IL49503A0 (en) 1973-02-14 1976-04-30 Novel benzophenone derivatives and their preparation

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL44068A IL44068A (en) 1973-02-14 1974-01-24 Process for the preparation of 6-phenyl-4h-s-triazolo(4,3a)(1,4)benzodiazepines and intermediate 2(2-(methanesulfonyl)methyl)-4h-1,2,4-triazol-4yl)benzophenones
IL49503A IL49503A0 (en) 1973-02-14 1976-04-30 Novel benzophenone derivatives and their preparation

Country Status (16)

Country Link
JP (1) JPS49110699A (xx)
AU (1) AU471038B2 (xx)
BE (1) BE811025A (xx)
CA (1) CA999000A (xx)
CH (2) CH586704A5 (xx)
DE (1) DE2402363A1 (xx)
DK (1) DK140803B (xx)
ES (2) ES422941A1 (xx)
FR (1) FR2217335B1 (xx)
GB (3) GB1454684A (xx)
HU (1) HU168136B (xx)
IL (3) IL49503A (xx)
NL (1) NL7400958A (xx)
PH (2) PH10784A (xx)
SE (2) SE423546B (xx)
ZA (1) ZA74466B (xx)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709898A (en) * 1971-02-09 1973-01-09 Upjohn Co Process for the production of triazolobenzodiazepines and intermediates

Also Published As

Publication number Publication date
IL49503A0 (en) 1976-06-30
PH11789A (en) 1978-07-05
AU471038B2 (en) 1976-04-08
GB1454682A (en) 1976-11-03
SE435285B (sv) 1984-09-17
CA999000A (en) 1976-10-26
CH587263A5 (xx) 1977-04-29
SE423546B (sv) 1982-05-10
ZA74466B (en) 1974-12-24
CH586704A5 (xx) 1977-04-15
DK140803C (xx) 1980-04-21
IL44068A (en) 1977-05-31
FR2217335B1 (xx) 1977-06-10
NL7400958A (xx) 1974-08-16
BE811025A (fr) 1974-08-14
PH10784A (en) 1977-09-06
DE2402363A1 (de) 1974-08-22
JPS49110699A (xx) 1974-10-22
SE8107017L (sv) 1981-11-25
DK140803B (da) 1979-11-19
IL44068A0 (en) 1974-05-16
ES422941A1 (es) 1976-09-16
AU6478674A (en) 1975-07-24
FR2217335A1 (xx) 1974-09-06
GB1454683A (en) 1976-11-03
ES445860A1 (es) 1977-05-01
GB1454684A (en) 1976-11-03
HU168136B (xx) 1976-02-28

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