IL47394A - ((imidazolyl or thiazolyl)alkyl(thio)alkyl) guanidine derivatives process for their preparation and pharmaceutical compositions containing them - Google Patents
((imidazolyl or thiazolyl)alkyl(thio)alkyl) guanidine derivatives process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL47394A IL47394A IL47394A IL4739475A IL47394A IL 47394 A IL47394 A IL 47394A IL 47394 A IL47394 A IL 47394A IL 4739475 A IL4739475 A IL 4739475A IL 47394 A IL47394 A IL 47394A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- thiazolyl
- imidazolyl
- thio
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28722/74A GB1497260A (en) | 1974-06-28 | 1974-06-28 | Guanidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL47394A0 IL47394A0 (en) | 1975-07-28 |
| IL47394A true IL47394A (en) | 1980-01-31 |
Family
ID=10280055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL47394A IL47394A (en) | 1974-06-28 | 1975-05-30 | ((imidazolyl or thiazolyl)alkyl(thio)alkyl) guanidine derivatives process for their preparation and pharmaceutical compositions containing them |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4034101A (fr) |
| JP (1) | JPS5946221B2 (fr) |
| AU (1) | AU503858B2 (fr) |
| BE (1) | BE830272A (fr) |
| CA (1) | CA1076579A (fr) |
| CH (1) | CH615669A5 (fr) |
| DE (1) | DE2528639A1 (fr) |
| DK (1) | DK268975A (fr) |
| ES (1) | ES438944A1 (fr) |
| FR (1) | FR2276042A1 (fr) |
| GB (1) | GB1497260A (fr) |
| IE (1) | IE41625B1 (fr) |
| IL (1) | IL47394A (fr) |
| LU (1) | LU72835A1 (fr) |
| NL (1) | NL7506951A (fr) |
| NO (1) | NO143942C (fr) |
| PH (1) | PH14275A (fr) |
| PL (1) | PL98616B1 (fr) |
| SE (1) | SE417961B (fr) |
| ZA (1) | ZA753455B (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5014808U (fr) * | 1973-06-06 | 1975-02-17 | ||
| JPS55822B2 (fr) * | 1973-07-09 | 1980-01-10 | ||
| US4197305A (en) * | 1974-02-07 | 1980-04-08 | Smith Kline & French Laboratories Limited | Thiazole, isothiazole, oxazole and isoxazole compounds |
| US4133886A (en) * | 1974-02-07 | 1979-01-09 | Smith Kline & French Laboratories Limited | Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine |
| GB1493931A (en) * | 1974-02-07 | 1977-11-30 | Smith Kline French Lab | Guanidines isothioureas and thioureas |
| GB1496787A (en) * | 1974-03-12 | 1978-01-05 | Smith Kline French Lab | Heteroalkylthioalkyl amidine derivatives |
| US4170652A (en) * | 1974-03-12 | 1979-10-09 | Smith Kline & French Laboratories Limited | Heterocyclic-methylthioalkyl-guanidines |
| JPS5912767Y2 (ja) * | 1974-03-28 | 1984-04-17 | アイワ カブシキガイシヤ | 回転機器の作動切換装置 |
| US4093729A (en) * | 1974-06-28 | 1978-06-06 | Smith Kline & French Laboratories Limited | N-Oxy and N-amino guanidines |
| US4192879A (en) * | 1975-05-21 | 1980-03-11 | Smith Kline & French Laboratories Limited | Imidazolyl alkylamino nitroethylene compounds |
| IL49528A (en) * | 1975-05-21 | 1980-11-30 | Smith Kline French Lab | Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them |
| GB1564502A (en) * | 1975-07-31 | 1980-04-10 | Smith Kline French Lab | Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives |
| NZ186965A (en) | 1977-04-20 | 1980-02-21 | Ici Ltd | Guanidino derivatives and pharmaceutical compositions |
| US4165378A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
| GB1602458A (en) * | 1977-05-05 | 1981-11-11 | Smith Kline French Lab | Bisamidines as histamine h2-antagonists |
| US4108859A (en) * | 1977-06-06 | 1978-08-22 | The Dow Chemical Company | Microbicidal (pyridinylamino) alkyl guanidines |
| US4233302A (en) | 1977-12-23 | 1980-11-11 | Glaxo Group Limited | Amine derivatives and pharmaceutical compositions containing them |
| EP0006679B1 (fr) | 1978-05-24 | 1982-07-21 | Imperial Chemical Industries Plc | Dérivés antisécréteurs de thiadiazole, procédé pour leur préparation et compositions pharmaceutiques les contenant |
| CA1140925A (fr) * | 1978-10-16 | 1983-02-08 | Derrick F. Jones | Derives heterocycliques anti-secretion, a chaine ramifiee, procedes pour les fabriquer et compositions pharmaceutiques qui en contiennent |
| JPS56124143A (en) * | 1980-02-29 | 1981-09-29 | Sanyo Electric Co Ltd | Control mechanism of tape recorder |
| AU2222083A (en) * | 1982-12-14 | 1984-06-21 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
| JPS6156012U (fr) * | 1984-09-19 | 1986-04-15 | ||
| JPS61228914A (ja) * | 1985-04-04 | 1986-10-13 | Sumitomo Heavy Ind Ltd | 成形用金型 |
| JPH0347862Y2 (fr) * | 1985-12-14 | 1991-10-14 | ||
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758146A (fr) * | 1969-10-29 | 1971-04-28 | Smith Kline French Lab | Derives de l'amidine |
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
-
1974
- 1974-06-28 GB GB28722/74A patent/GB1497260A/en not_active Expired
-
1975
- 1975-05-28 ZA ZA00753455A patent/ZA753455B/xx unknown
- 1975-05-30 IL IL47394A patent/IL47394A/xx unknown
- 1975-06-09 IE IE1299/75A patent/IE41625B1/en unknown
- 1975-06-11 US US05/585,898 patent/US4034101A/en not_active Expired - Lifetime
- 1975-06-11 NL NL7506951A patent/NL7506951A/xx not_active Application Discontinuation
- 1975-06-12 CA CA229,222A patent/CA1076579A/fr not_active Expired
- 1975-06-13 DK DK268975A patent/DK268975A/da not_active Application Discontinuation
- 1975-06-16 BE BE157354A patent/BE830272A/fr not_active IP Right Cessation
- 1975-06-20 AU AU82304/75A patent/AU503858B2/en not_active Ceased
- 1975-06-20 PH PH17301A patent/PH14275A/en unknown
- 1975-06-24 FR FR7519669A patent/FR2276042A1/fr active Granted
- 1975-06-24 JP JP50079233A patent/JPS5946221B2/ja not_active Expired
- 1975-06-26 DE DE19752528639 patent/DE2528639A1/de not_active Withdrawn
- 1975-06-26 LU LU72835A patent/LU72835A1/xx unknown
- 1975-06-26 SE SE7507364A patent/SE417961B/xx unknown
- 1975-06-27 NO NO752330A patent/NO143942C/no unknown
- 1975-06-27 CH CH838175A patent/CH615669A5/de not_active IP Right Cessation
- 1975-06-27 ES ES438944A patent/ES438944A1/es not_active Expired
- 1975-06-27 PL PL1975181592A patent/PL98616B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2276042A1 (fr) | 1976-01-23 |
| NL7506951A (nl) | 1975-12-30 |
| AU503858B2 (en) | 1979-09-27 |
| GB1497260A (en) | 1978-01-05 |
| FR2276042B1 (fr) | 1980-04-25 |
| LU72835A1 (fr) | 1975-10-08 |
| NO143942C (no) | 1981-05-13 |
| ZA753455B (en) | 1976-04-28 |
| NO752330L (fr) | 1975-12-30 |
| PL98616B1 (pl) | 1978-05-31 |
| SE417961B (sv) | 1981-04-27 |
| ES438944A1 (es) | 1977-02-16 |
| AU8230475A (en) | 1976-12-23 |
| US4034101A (en) | 1977-07-05 |
| CA1076579A (fr) | 1980-04-29 |
| JPS5119766A (fr) | 1976-02-17 |
| SE7507364L (sv) | 1975-12-29 |
| IE41625L (en) | 1975-12-28 |
| IE41625B1 (en) | 1980-02-13 |
| IL47394A0 (en) | 1975-07-28 |
| PH14275A (en) | 1981-04-29 |
| JPS5946221B2 (ja) | 1984-11-10 |
| NO143942B (no) | 1981-02-02 |
| DK268975A (da) | 1975-12-29 |
| CH615669A5 (fr) | 1980-02-15 |
| DE2528639A1 (de) | 1976-01-15 |
| BE830272A (fr) | 1975-12-16 |
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