IL43927A - Lysino-calcium chloride and acid addition salts thereof their preparation and pharmaceutical compositions containing them - Google Patents
Lysino-calcium chloride and acid addition salts thereof their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL43927A IL43927A IL43927A IL4392773A IL43927A IL 43927 A IL43927 A IL 43927A IL 43927 A IL43927 A IL 43927A IL 4392773 A IL4392773 A IL 4392773A IL 43927 A IL43927 A IL 43927A
- Authority
- IL
- Israel
- Prior art keywords
- lysino
- calcium chloride
- namely
- calcium
- salt
- Prior art date
Links
- 239000001110 calcium chloride Substances 0.000 title claims abstract 22
- 229910001628 calcium chloride Inorganic materials 0.000 title claims abstract 22
- 150000003839 salts Chemical class 0.000 title claims abstract 21
- 239000002253 acid Substances 0.000 title claims abstract 9
- 238000002360 preparation method Methods 0.000 title claims abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 3
- 238000000034 method Methods 0.000 claims abstract 16
- 206010006956 Calcium deficiency Diseases 0.000 claims abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 10
- BVHLGVCQOALMSV-JEDNCBNOSA-N L-lysine hydrochloride Chemical compound Cl.NCCCC[C@H](N)C(O)=O BVHLGVCQOALMSV-JEDNCBNOSA-N 0.000 claims 6
- 230000001476 alcoholic effect Effects 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- UYMMKPRUXNBFTL-XRIGFGBMSA-M [Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] Chemical compound [Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] UYMMKPRUXNBFTL-XRIGFGBMSA-M 0.000 claims 3
- 229940043430 calcium compound Drugs 0.000 claims 3
- 150000001674 calcium compounds Chemical class 0.000 claims 3
- -1 salicylic Chemical group 0.000 claims 3
- HEOIAZNPQJLLAM-BHRFRFAJSA-M C(CC(O)(C(=O)O)CC(=O)O)(=O)O.[Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] Chemical compound C(CC(O)(C(=O)O)CC(=O)O)(=O)O.[Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] HEOIAZNPQJLLAM-BHRFRFAJSA-M 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 230000005587 bubbling Effects 0.000 claims 2
- 239000001569 carbon dioxide Substances 0.000 claims 2
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 2
- 125000005273 2-acetoxybenzoic acid group Chemical group 0.000 claims 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 1
- COVZYZSDYWQREU-UHFFFAOYSA-N Busulfan Chemical compound CS(=O)(=O)OCCCCOS(C)(=O)=O COVZYZSDYWQREU-UHFFFAOYSA-N 0.000 claims 1
- HCNXEVJCRMVJKE-BHRFRFAJSA-M C(O)(O)=O.[Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] Chemical compound C(O)(O)=O.[Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] HCNXEVJCRMVJKE-BHRFRFAJSA-M 0.000 claims 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- BRLIMPSRZNVHKS-BHRFRFAJSA-M Cl.[Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] Chemical compound Cl.[Cl-].N([C@@H](CCCCN)C(=O)O)[Ca+] BRLIMPSRZNVHKS-BHRFRFAJSA-M 0.000 claims 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 claims 1
- 208000006558 Dental Calculus Diseases 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 1
- 235000019445 benzyl alcohol Nutrition 0.000 claims 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims 1
- 239000000920 calcium hydroxide Substances 0.000 claims 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims 1
- 239000000292 calcium oxide Substances 0.000 claims 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 229940050410 gluconate Drugs 0.000 claims 1
- UWYVPFMHMJIBHE-OWOJBTEDSA-N hydroxymaleic acid group Chemical group O/C(/C(=O)O)=C/C(=O)O UWYVPFMHMJIBHE-OWOJBTEDSA-N 0.000 claims 1
- 239000012429 reaction media Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000011575 calcium Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB19273*[A GB1394757A (en) | 1973-01-02 | 1973-01-02 | Lysino-calcium chloride |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL43927A0 IL43927A0 (en) | 1974-03-14 |
| IL43927A true IL43927A (en) | 1976-10-31 |
Family
ID=9700038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL43927A IL43927A (en) | 1973-01-02 | 1973-12-28 | Lysino-calcium chloride and acid addition salts thereof their preparation and pharmaceutical compositions containing them |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US3928506A (cs) |
| JP (1) | JPS5810377B2 (cs) |
| AR (1) | AR200042A1 (cs) |
| AT (1) | AT323125B (cs) |
| AU (1) | AU475433B2 (cs) |
| BE (1) | BE809324A (cs) |
| CA (1) | CA1000288A (cs) |
| CH (1) | CH591422A5 (cs) |
| CS (1) | CS174121B2 (cs) |
| DD (1) | DD110488A5 (cs) |
| DE (1) | DE2364704C2 (cs) |
| ES (1) | ES421854A1 (cs) |
| FR (1) | FR2212151B1 (cs) |
| GB (1) | GB1394757A (cs) |
| HK (1) | HK23376A (cs) |
| HU (1) | HU168134B (cs) |
| IL (1) | IL43927A (cs) |
| IN (1) | IN140693B (cs) |
| NL (1) | NL179277C (cs) |
| PL (1) | PL89632B1 (cs) |
| RO (1) | RO64583A (cs) |
| SE (1) | SE398874B (cs) |
| SU (1) | SU504479A3 (cs) |
| YU (1) | YU36152B (cs) |
| ZA (1) | ZA739698B (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4948594A (en) * | 1989-01-03 | 1990-08-14 | Zinpro Corporation | Copper complexes of alpha-amino acids that contain terminal amino groups, and their use as nutritional supplements |
| US4900561A (en) * | 1989-01-03 | 1990-02-13 | Zinpro Corporation | Copper complexes of alpha-amino acids that contain terminal amino groups, and their use as nutritional supplements |
| US5885610A (en) * | 1997-03-04 | 1999-03-23 | Zinpro Corporation | By-pass rumen product |
| US6294207B1 (en) * | 1999-11-01 | 2001-09-25 | Albion International, Inc. | Calcium fortification of oleaginous foods |
| AR055285A1 (es) * | 2005-11-11 | 2007-08-15 | Edgardo Adrian Hager | Sales de nutrientes minerales estabilizados con aminoacidos productos y suplemento alimenticio que las comprenden y procedimientos de obtencion |
| CN105777534B (zh) * | 2014-12-24 | 2018-07-06 | 辽宁科硕营养科技有限公司 | 柠檬酸钙盐及其制备方法与用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2386273A (en) * | 1943-01-15 | 1945-10-09 | Lilly Co Eli | Carbonates of 1-r-1 aminoethanes |
| US2833821A (en) * | 1954-10-07 | 1958-05-06 | Du Pont | Preparation of calcium lysinate |
| US3010972A (en) * | 1960-03-18 | 1961-11-28 | Smith Kline French Lab | Condensed cyclopropyl amine derivatives |
| US3355488A (en) * | 1964-04-13 | 1967-11-28 | Squibb & Sons Inc | Calcium chloride salt of penicillamine |
-
1973
- 1973-01-02 GB GB19273*[A patent/GB1394757A/en not_active Expired
- 1973-12-21 SE SE7317391A patent/SE398874B/xx unknown
- 1973-12-21 NL NLAANVRAGE7317589,A patent/NL179277C/xx not_active IP Right Cessation
- 1973-12-24 JP JP744651A patent/JPS5810377B2/ja not_active Expired
- 1973-12-27 ZA ZA739698A patent/ZA739698B/xx unknown
- 1973-12-27 AU AU63945/73A patent/AU475433B2/en not_active Expired
- 1973-12-27 DE DE2364704A patent/DE2364704C2/de not_active Expired
- 1973-12-27 AR AR251718A patent/AR200042A1/es active
- 1973-12-27 CA CA189,027A patent/CA1000288A/en not_active Expired
- 1973-12-27 DD DD175692A patent/DD110488A5/xx unknown
- 1973-12-27 CH CH1813873A patent/CH591422A5/xx not_active IP Right Cessation
- 1973-12-27 FR FR7347178A patent/FR2212151B1/fr not_active Expired
- 1973-12-28 ES ES421854A patent/ES421854A1/es not_active Expired
- 1973-12-28 RO RO7300077158A patent/RO64583A/ro unknown
- 1973-12-28 YU YU3385/73A patent/YU36152B/xx unknown
- 1973-12-28 AT AT1088973AA patent/AT323125B/de not_active IP Right Cessation
- 1973-12-28 HU HUUE44A patent/HU168134B/hu unknown
- 1973-12-28 US US429297A patent/US3928506A/en not_active Expired - Lifetime
- 1973-12-28 SU SU1983085A patent/SU504479A3/ru active
- 1973-12-28 IN IN2829/CAL/73A patent/IN140693B/en unknown
- 1973-12-28 IL IL43927A patent/IL43927A/en unknown
-
1974
- 1974-01-02 CS CS20A patent/CS174121B2/cs unknown
- 1974-01-02 PL PL1974167896A patent/PL89632B1/pl unknown
- 1974-01-02 BE BE1005619A patent/BE809324A/xx not_active IP Right Cessation
-
1976
- 1976-04-22 HK HK233/76*UA patent/HK23376A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD110488A5 (cs) | 1974-12-20 |
| NL179277C (nl) | 1986-08-18 |
| HU168134B (cs) | 1976-02-28 |
| IN140693B (cs) | 1976-12-11 |
| AT323125B (de) | 1975-06-25 |
| DE2364704C2 (de) | 1985-03-21 |
| YU338573A (en) | 1981-06-30 |
| GB1394757A (en) | 1975-05-21 |
| ZA739698B (en) | 1974-11-27 |
| RO64583A (fr) | 1978-07-15 |
| JPS49100214A (cs) | 1974-09-21 |
| PL89632B1 (cs) | 1976-11-30 |
| AU475433B2 (en) | 1976-08-19 |
| SE398874B (sv) | 1978-01-23 |
| AR200042A1 (es) | 1974-10-15 |
| JPS5810377B2 (ja) | 1983-02-25 |
| FR2212151A1 (cs) | 1974-07-26 |
| DE2364704A1 (de) | 1974-09-05 |
| AU6394573A (en) | 1975-07-03 |
| CH591422A5 (cs) | 1977-09-15 |
| BE809324A (fr) | 1974-07-02 |
| NL7317589A (cs) | 1974-07-04 |
| HK23376A (en) | 1976-04-30 |
| CA1000288A (en) | 1976-11-23 |
| ES421854A1 (es) | 1976-08-01 |
| US3928506A (en) | 1975-12-23 |
| IL43927A0 (en) | 1974-03-14 |
| NL179277B (nl) | 1986-03-17 |
| CS174121B2 (cs) | 1977-03-31 |
| SU504479A3 (ru) | 1976-02-25 |
| YU36152B (en) | 1982-02-25 |
| FR2212151B1 (cs) | 1978-01-06 |
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