IL42472A - Dialkylaminoalkyl esters of 6-methoxy-2-naphthylpropionic acid and salts thereof and their preparation - Google Patents

Dialkylaminoalkyl esters of 6-methoxy-2-naphthylpropionic acid and salts thereof and their preparation

Info

Publication number
IL42472A
IL42472A IL42472A IL4247273A IL42472A IL 42472 A IL42472 A IL 42472A IL 42472 A IL42472 A IL 42472A IL 4247273 A IL4247273 A IL 4247273A IL 42472 A IL42472 A IL 42472A
Authority
IL
Israel
Prior art keywords
methoxy
naphthyl
naphthy1
propionate
compound
Prior art date
Application number
IL42472A
Other languages
English (en)
Other versions
IL42472A0 (en
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Corp filed Critical Syntex Corp
Publication of IL42472A0 publication Critical patent/IL42472A0/xx
Publication of IL42472A publication Critical patent/IL42472A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/14—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL42472A 1972-06-27 1973-06-11 Dialkylaminoalkyl esters of 6-methoxy-2-naphthylpropionic acid and salts thereof and their preparation IL42472A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26664072A 1972-06-27 1972-06-27

Publications (2)

Publication Number Publication Date
IL42472A0 IL42472A0 (en) 1973-08-29
IL42472A true IL42472A (en) 1977-01-31

Family

ID=23015387

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42472A IL42472A (en) 1972-06-27 1973-06-11 Dialkylaminoalkyl esters of 6-methoxy-2-naphthylpropionic acid and salts thereof and their preparation

Country Status (13)

Country Link
JP (1) JPS5438097B2 (fr)
AT (1) AT323145B (fr)
AU (1) AU472375B2 (fr)
BE (1) BE801440A (fr)
CA (1) CA1012159A (fr)
CH (1) CH581605A5 (fr)
DE (1) DE2331665C2 (fr)
ES (1) ES416311A1 (fr)
FR (1) FR2190451B1 (fr)
GB (1) GB1377316A (fr)
IL (1) IL42472A (fr)
NL (1) NL175910C (fr)
ZA (1) ZA733992B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1508988A (en) * 1987-04-27 1988-10-27 Syntex Pharmaceuticals International Ltd. Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs
CA2660814C (fr) * 2006-08-15 2017-07-18 Techfields Biochem Co. Ltd Promedicaments hydrosolubles charges positivement contenant des acides aryl- et heteroarylpropioniques et dotes d'une tres grande vitesse de penetration cutanee
KR101366296B1 (ko) * 2012-03-07 2014-02-21 주식회사 포스코 내화재 축조 방법
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI41272B (fr) * 1963-05-02 1969-06-30 Parke Davis & Co
ZA701191B (en) * 1969-03-24 1971-09-29 Syntex Corp 2-(6-substituted-2'-naphthyl)acetic acid esters and process for producing same

Also Published As

Publication number Publication date
FR2190451B1 (fr) 1976-12-31
JPS5438097B2 (fr) 1979-11-19
BE801440A (fr) 1973-12-26
FR2190451A1 (fr) 1974-02-01
ZA733992B (en) 1975-01-29
NL175910C (nl) 1985-01-16
NL7308876A (fr) 1974-01-02
CA1012159A (en) 1977-06-14
AU472375B2 (en) 1976-05-20
CH581605A5 (fr) 1976-11-15
JPS504053A (fr) 1975-01-16
ES416311A1 (es) 1976-05-16
NL175910B (nl) 1984-08-16
IL42472A0 (en) 1973-08-29
AT323145B (de) 1975-06-25
AU5690373A (en) 1974-12-19
GB1377316A (en) 1974-12-11
DE2331665C2 (de) 1983-04-21
DE2331665A1 (de) 1974-01-17

Similar Documents

Publication Publication Date Title
US3663584A (en) Di-(6-methoxy-2-naphthyl)zinc and 6-methoxy-2-naphthylzinc halide
US3658863A (en) 6-methoxy-2-naphthyl copper(i)
US3468939A (en) 4- and 5-aryl-1-naphthaleneacetic acid compounds
US3975432A (en) Process for preparing 2-(6-methoxy-2-naphthyl)propionic acid
IL42472A (en) Dialkylaminoalkyl esters of 6-methoxy-2-naphthylpropionic acid and salts thereof and their preparation
KR0146352B1 (ko) 모르니플루메이트 및 동족 화합물의 제조방법
KR100317147B1 (ko) 3-(2-아미노-4-티아졸릴)-ｌ-알라닌 및 그의 제조 방법
US3694476A (en) (6-methoxy-2-napthyl) cadmium halide
IL38023A (en) Isoindoline derivatives and process for their preparation
US4118504A (en) Isoindoline derivatives for treating pain
EP0465879B1 (fr) Dérivés de l'acide 4-(2,4-difluorobiphénylyl)-2-méthyl-4-oxobutanoique
US4532249A (en) Derivatives of p-acylaminophenol having a therapeutic action, and compositions having a therapeutic action containing said derivatives as pharmacologically active ingredients
US4233304A (en) Pyridoxine derivatives
JPH0665269A (ja) ホスホン酸ジエステル誘導体
US4005146A (en) Resolution of dl-allethrolone
US4264500A (en) Process of making 6-chloro-α-methyl-carbazole-2-acetic acid
US3465002A (en) (succinimidoaryloxy)alkanoic acids,esters and amides thereof
EP0437566B1 (fr) Derives de phenyle-glycine
SU1034605A3 (ru) Способ получени молекул рного соединени @ -диэтиламиноэтиламида @ -хлорфеноксиуксусной кислоты с 4- @ -бутил-3,5-дикето-1,2-дифенилпиразолидином
US3244725A (en) 4, 5-diacyl-3-hydroxy-3-pyrrolin-2-ones
US3792082A (en) Esters of halophenoxyisobutyric acid and hydroxy-aliphatic acid derivatives
US4002655A (en) Glycyrrhetinic acid derivatives
DE2943809A1 (de) 1-mercaptoacylpiperazin-2-carbonsaeure-verbindungen und ihre salze, verfahren zu ihrer herstellung und ihre verwendung bei der bekaempfung von hypertonie
US5849725A (en) Phosphorylated derivatives of compositions having anti-inflammatory or analgesic activity and a method for the preparation thereof
SU626693A3 (ru) Способ получени 1-этил-2-(2-метокси-5 -сульфонамидобензоил)аминометилпирролидина или его солей