ZA733992B - Diaalkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof - Google Patents

Diaalkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof

Info

Publication number
ZA733992B
ZA733992B ZA00733992A ZA733992A ZA733992B ZA 733992 B ZA733992 B ZA 733992B ZA 00733992 A ZA00733992 A ZA 00733992A ZA 733992 A ZA733992 A ZA 733992A ZA 733992 B ZA733992 B ZA 733992B
Authority
ZA
South Africa
Prior art keywords
diaalkylaminoalkyl
esters
acid addition
addition salts
arylaliphatic acids
Prior art date
Application number
ZA00733992A
Other languages
English (en)
Inventor
M Marx
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Corp filed Critical Syntex Corp
Publication of ZA733992B publication Critical patent/ZA733992B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/14Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00733992A 1972-06-27 1973-06-12 Diaalkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof ZA733992B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26664072A 1972-06-27 1972-06-27

Publications (1)

Publication Number Publication Date
ZA733992B true ZA733992B (en) 1975-01-29

Family

ID=23015387

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00733992A ZA733992B (en) 1972-06-27 1973-06-12 Diaalkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof

Country Status (13)

Country Link
JP (1) JPS5438097B2 (xx)
AT (1) AT323145B (xx)
AU (1) AU472375B2 (xx)
BE (1) BE801440A (xx)
CA (1) CA1012159A (xx)
CH (1) CH581605A5 (xx)
DE (1) DE2331665C2 (xx)
ES (1) ES416311A1 (xx)
FR (1) FR2190451B1 (xx)
GB (1) GB1377316A (xx)
IL (1) IL42472A (xx)
NL (1) NL175910C (xx)
ZA (1) ZA733992B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA882957B (en) * 1987-04-27 1989-12-27 Syntex Pharma Int Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal anti-inflammatory drugs
JP5424880B2 (ja) * 2006-08-15 2014-02-26 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
KR101366296B1 (ko) * 2012-03-07 2014-02-21 주식회사 포스코 내화재 축조 방법
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE328272B (xx) * 1963-05-02 1970-09-14 Parke Davis & Co
ZA701191B (en) * 1969-03-24 1971-09-29 Syntex Corp 2-(6-substituted-2'-naphthyl)acetic acid esters and process for producing same

Also Published As

Publication number Publication date
NL175910B (nl) 1984-08-16
GB1377316A (en) 1974-12-11
ES416311A1 (es) 1976-05-16
CA1012159A (en) 1977-06-14
JPS5438097B2 (xx) 1979-11-19
IL42472A (en) 1977-01-31
IL42472A0 (en) 1973-08-29
NL175910C (nl) 1985-01-16
DE2331665C2 (de) 1983-04-21
FR2190451B1 (xx) 1976-12-31
CH581605A5 (xx) 1976-11-15
JPS504053A (xx) 1975-01-16
BE801440A (fr) 1973-12-26
DE2331665A1 (de) 1974-01-17
NL7308876A (xx) 1974-01-02
FR2190451A1 (xx) 1974-02-01
AU472375B2 (en) 1976-05-20
AU5690373A (en) 1974-12-19
AT323145B (de) 1975-06-25

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