AT323145B - Verfahren zur herstellung neuer dialkylaminoester der 2-(6-methoxy-2-naphthyl)-propionsäure und ihren säureadditionssalzen - Google Patents

Verfahren zur herstellung neuer dialkylaminoester der 2-(6-methoxy-2-naphthyl)-propionsäure und ihren säureadditionssalzen

Info

Publication number
AT323145B
AT323145B AT528473A AT528473A AT323145B AT 323145 B AT323145 B AT 323145B AT 528473 A AT528473 A AT 528473A AT 528473 A AT528473 A AT 528473A AT 323145 B AT323145 B AT 323145B
Authority
AT
Austria
Prior art keywords
dialkylaminoesters
naphthyl
methoxy
new
production
Prior art date
Application number
AT528473A
Other languages
German (de)
English (en)
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Corp filed Critical Syntex Corp
Application granted granted Critical
Publication of AT323145B publication Critical patent/AT323145B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/14Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT528473A 1972-06-27 1973-06-15 Verfahren zur herstellung neuer dialkylaminoester der 2-(6-methoxy-2-naphthyl)-propionsäure und ihren säureadditionssalzen AT323145B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26664072A 1972-06-27 1972-06-27

Publications (1)

Publication Number Publication Date
AT323145B true AT323145B (de) 1975-06-25

Family

ID=23015387

Family Applications (1)

Application Number Title Priority Date Filing Date
AT528473A AT323145B (de) 1972-06-27 1973-06-15 Verfahren zur herstellung neuer dialkylaminoester der 2-(6-methoxy-2-naphthyl)-propionsäure und ihren säureadditionssalzen

Country Status (13)

Country Link
JP (1) JPS5438097B2 (xx)
AT (1) AT323145B (xx)
AU (1) AU472375B2 (xx)
BE (1) BE801440A (xx)
CA (1) CA1012159A (xx)
CH (1) CH581605A5 (xx)
DE (1) DE2331665C2 (xx)
ES (1) ES416311A1 (xx)
FR (1) FR2190451B1 (xx)
GB (1) GB1377316A (xx)
IL (1) IL42472A (xx)
NL (1) NL175910C (xx)
ZA (1) ZA733992B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1508988A (en) * 1987-04-27 1988-10-27 Syntex Pharmaceuticals International Ltd. Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs
CA2660814C (en) * 2006-08-15 2017-07-18 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
KR101366296B1 (ko) * 2012-03-07 2014-02-21 주식회사 포스코 내화재 축조 방법
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI41272B (xx) * 1963-05-02 1969-06-30 Parke Davis & Co
ZA701191B (en) * 1969-03-24 1971-09-29 Syntex Corp 2-(6-substituted-2'-naphthyl)acetic acid esters and process for producing same

Also Published As

Publication number Publication date
FR2190451B1 (xx) 1976-12-31
JPS5438097B2 (xx) 1979-11-19
BE801440A (fr) 1973-12-26
FR2190451A1 (xx) 1974-02-01
ZA733992B (en) 1975-01-29
NL175910C (nl) 1985-01-16
NL7308876A (xx) 1974-01-02
CA1012159A (en) 1977-06-14
AU472375B2 (en) 1976-05-20
CH581605A5 (xx) 1976-11-15
JPS504053A (xx) 1975-01-16
ES416311A1 (es) 1976-05-16
NL175910B (nl) 1984-08-16
IL42472A0 (en) 1973-08-29
IL42472A (en) 1977-01-31
AU5690373A (en) 1974-12-19
GB1377316A (en) 1974-12-11
DE2331665C2 (de) 1983-04-21
DE2331665A1 (de) 1974-01-17

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee