IL41413A - 3-(1-lower alkyl-4(or 5)-nitro-2-imidazolyl)-4-imidazoline-2-thiones and their manufacture - Google Patents
3-(1-lower alkyl-4(or 5)-nitro-2-imidazolyl)-4-imidazoline-2-thiones and their manufactureInfo
- Publication number
- IL41413A IL41413A IL41413A IL4141373A IL41413A IL 41413 A IL41413 A IL 41413A IL 41413 A IL41413 A IL 41413A IL 4141373 A IL4141373 A IL 4141373A IL 41413 A IL41413 A IL 41413A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- group
- compounds
- nitro
- lower alkyl
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 150000001875 compounds Chemical class 0.000 claims 15
- 238000000034 method Methods 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 125000000464 thioxo group Chemical group S=* 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- -1 sulphonyl group Chemical group 0.000 claims 3
- 239000002585 base Substances 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000003287 optical effect Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 101100260565 Dictyostelium discoideum thyA gene Proteins 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 229910000102 alkali metal hydride Inorganic materials 0.000 claims 1
- 150000008046 alkali metal hydrides Chemical class 0.000 claims 1
- 150000001340 alkali metals Chemical group 0.000 claims 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000005494 condensation Effects 0.000 claims 1
- 238000009833 condensation Methods 0.000 claims 1
- 239000012433 hydrogen halide Substances 0.000 claims 1
- 229910000039 hydrogen halide Inorganic materials 0.000 claims 1
- 238000006317 isomerization reaction Methods 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124531 pharmaceutical excipient Drugs 0.000 claims 1
- 239000002798 polar solvent Substances 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
- 101150068774 thyX gene Proteins 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH181072A CH570399A5 (en) | 1972-02-08 | 1972-02-08 | 4-or-5-nitro-imidazole derivs - with antibacterial, antiprotozoal and anthelmintic activity |
| CH1886772 | 1972-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41413A0 IL41413A0 (en) | 1973-03-30 |
| IL41413A true IL41413A (en) | 1976-11-30 |
Family
ID=25688733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41413A IL41413A (en) | 1972-02-08 | 1973-01-29 | 3-(1-lower alkyl-4(or 5)-nitro-2-imidazolyl)-4-imidazoline-2-thiones and their manufacture |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3914248A (en, 2012) |
| JP (1) | JPS4886867A (en, 2012) |
| AR (2) | AR205433A1 (en, 2012) |
| AT (1) | AT320639B (en, 2012) |
| BE (1) | BE795068A (en, 2012) |
| BG (2) | BG19804A3 (en, 2012) |
| CA (1) | CA1018982A (en, 2012) |
| DD (1) | DD106039A5 (en, 2012) |
| DE (1) | DE2304508A1 (en, 2012) |
| EG (1) | EG11076A (en, 2012) |
| FR (1) | FR2181707B1 (en, 2012) |
| GB (1) | GB1392015A (en, 2012) |
| HU (1) | HU166379B (en, 2012) |
| IE (1) | IE37253B1 (en, 2012) |
| IL (1) | IL41413A (en, 2012) |
| NL (1) | NL7301602A (en, 2012) |
| NO (1) | NO137275B (en, 2012) |
| OA (1) | OA04651A (en, 2012) |
| PH (1) | PH11056A (en, 2012) |
| SU (1) | SU482044A3 (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH592653A5 (en, 2012) * | 1973-09-24 | 1977-10-31 | Ciba Geigy Ag | |
| FR2300563A1 (fr) * | 1975-02-13 | 1976-09-10 | Sandoz Sa | Nouveaux derives du thiazole, leur preparation et leur application comme medicaments |
| US5057613A (en) * | 1986-05-06 | 1991-10-15 | Merrell Dow Pharmaceuticals | Novel thione dopamine beta hydroxylase inhibitors |
| FR2680791B1 (fr) * | 1991-08-30 | 1994-09-09 | Bp Chemicals Snc | Procede de fabrication d'un polymere reticule et utilisation du polymere. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3642836A (en) * | 1969-02-03 | 1972-02-15 | Searle & Co | N-(2-(2-methyl-5-nitro-1-imidazolyl)ethyl)imides |
| IL39283A (en) * | 1971-05-03 | 1976-01-30 | Ciba Geigy Ag | Substituted 2-oxo or thioxo-3-(5-nitro-imidazol-2-yl)-tetrahydroimidazoles and their manufacture |
-
0
- BE BE795068D patent/BE795068A/xx unknown
-
1973
- 1973-01-01 AR AR246475A patent/AR205433A1/es active
- 1973-01-26 IE IE130/73A patent/IE37253B1/xx unknown
- 1973-01-29 IL IL41413A patent/IL41413A/en unknown
- 1973-01-31 DE DE2304508A patent/DE2304508A1/de active Pending
- 1973-01-31 CA CA162,478A patent/CA1018982A/en not_active Expired
- 1973-01-31 US US328816*A patent/US3914248A/en not_active Expired - Lifetime
- 1973-02-02 SU SU1878870A patent/SU482044A3/ru active
- 1973-02-02 NO NO439/73A patent/NO137275B/no unknown
- 1973-02-05 NL NL7301602A patent/NL7301602A/xx unknown
- 1973-02-06 PH PH14314A patent/PH11056A/en unknown
- 1973-02-06 AT AT103973A patent/AT320639B/de not_active IP Right Cessation
- 1973-02-06 DD DD168733A patent/DD106039A5/xx unknown
- 1973-02-06 BG BG023406A patent/BG19804A3/xx unknown
- 1973-02-06 BG BG022636A patent/BG19803A3/xx unknown
- 1973-02-06 FR FR7304100A patent/FR2181707B1/fr not_active Expired
- 1973-02-07 HU HUCI1338A patent/HU166379B/hu unknown
- 1973-02-07 OA OA54827A patent/OA04651A/xx unknown
- 1973-02-08 JP JP48015231A patent/JPS4886867A/ja active Pending
- 1973-02-08 GB GB624573A patent/GB1392015A/en not_active Expired
- 1973-02-08 EG EG50/73A patent/EG11076A/xx active
- 1973-11-05 AR AR250842A patent/AR208880A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| IE37253L (en) | 1973-08-08 |
| AR205433A1 (es) | 1976-05-07 |
| IE37253B1 (en) | 1977-06-08 |
| BG19804A3 (bg) | 1975-10-10 |
| GB1392015A (en) | 1975-04-23 |
| AT320639B (de) | 1975-02-25 |
| DD106039A5 (en, 2012) | 1974-05-20 |
| CA1018982A (en) | 1977-10-11 |
| IL41413A0 (en) | 1973-03-30 |
| OA04651A (fr) | 1980-07-31 |
| US3914248A (en) | 1975-10-21 |
| JPS4886867A (en, 2012) | 1973-11-15 |
| HU166379B (en, 2012) | 1975-03-28 |
| PH11056A (en) | 1977-10-25 |
| NL7301602A (en, 2012) | 1973-08-10 |
| FR2181707A1 (en, 2012) | 1973-12-07 |
| FR2181707B1 (en, 2012) | 1976-04-09 |
| NO137275B (no) | 1977-10-24 |
| SU482044A3 (ru) | 1975-08-25 |
| BG19803A3 (bg) | 1975-10-10 |
| EG11076A (en) | 1976-11-30 |
| AR208880A1 (es) | 1977-03-15 |
| DE2304508A1 (de) | 1973-08-16 |
| BE795068A (fr) | 1973-08-07 |
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