IL41130A - Fused indole and indene derivatives and their preparation - Google Patents
Fused indole and indene derivatives and their preparationInfo
- Publication number
- IL41130A IL41130A IL41130A IL4113072A IL41130A IL 41130 A IL41130 A IL 41130A IL 41130 A IL41130 A IL 41130A IL 4113072 A IL4113072 A IL 4113072A IL 41130 A IL41130 A IL 41130A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- formula
- treating
- hydrogen
- group
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 2
- 125000003454 indenyl group Chemical class C1(C=CC2=CC=CC=C12)* 0.000 title 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 54
- 239000001257 hydrogen Substances 0.000 claims 18
- 229910052739 hydrogen Inorganic materials 0.000 claims 18
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 15
- 239000002253 acid Substances 0.000 claims 13
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 230000009466 transformation Effects 0.000 claims 8
- 150000001412 amines Chemical class 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 125000002947 alkylene group Chemical group 0.000 claims 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
- 230000003301 hydrolyzing effect Effects 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 3
- 125000000446 sulfanediyl group Chemical group *S* 0.000 claims 3
- 239000003377 acid catalyst Substances 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 150000001408 amides Chemical class 0.000 claims 2
- 150000008064 anhydrides Chemical class 0.000 claims 2
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 2
- 150000003138 primary alcohols Chemical class 0.000 claims 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 1
- 101100490437 Mus musculus Acvrl1 gene Proteins 0.000 claims 1
- 241000282320 Panthera leo Species 0.000 claims 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical group OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- 229940125782 compound 2 Drugs 0.000 claims 1
- 229940126214 compound 3 Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- -1 piperazino Chemical group 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 238000010561 standard procedure Methods 0.000 claims 1
- 238000000844 transformation Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/02—Thiols having mercapto groups bound to acyclic carbon atoms
- C07C321/10—Thiols having mercapto groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00217627A US3852285A (en) | 1972-01-13 | 1972-01-13 | Pyrano- and thiopyranoindole derivatives |
| US00226287A US3833575A (en) | 1972-02-14 | 1972-02-14 | Oxazinoindole-and thiazinoindole derivatives |
| US29712972A | 1972-10-12 | 1972-10-12 | |
| US297130A US3904617A (en) | 1972-10-12 | 1972-10-12 | Process for preparing new heterocyclic derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41130A0 IL41130A0 (en) | 1973-02-28 |
| IL41130A true IL41130A (en) | 1976-05-31 |
Family
ID=27499082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41130A IL41130A (en) | 1972-01-13 | 1972-12-20 | Fused indole and indene derivatives and their preparation |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE793978A (enrdf_load_stackoverflow) |
| CH (3) | CH606030A5 (enrdf_load_stackoverflow) |
| DK (1) | DK141201B (enrdf_load_stackoverflow) |
| IL (1) | IL41130A (enrdf_load_stackoverflow) |
| NL (1) | NL7300518A (enrdf_load_stackoverflow) |
| SE (1) | SE392274B (enrdf_load_stackoverflow) |
| SU (1) | SU728716A3 (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1683521A1 (en) * | 2005-01-21 | 2006-07-26 | Centre National De La Recherche Scientifique (Cnrs) | Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same |
-
0
- BE BE793978D patent/BE793978A/xx not_active IP Right Cessation
-
1972
- 1972-12-20 IL IL41130A patent/IL41130A/en unknown
-
1973
- 1973-01-12 CH CH1530677A patent/CH606030A5/xx not_active IP Right Cessation
- 1973-01-12 DK DK20973AA patent/DK141201B/da unknown
- 1973-01-12 CH CH48773A patent/CH605959A5/de not_active IP Right Cessation
- 1973-01-12 SE SE7300471A patent/SE392274B/xx unknown
- 1973-01-12 NL NL7300518A patent/NL7300518A/xx not_active Application Discontinuation
- 1973-01-12 SU SU731873352A patent/SU728716A3/ru active
- 1973-01-12 CH CH1530777A patent/CH606031A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SU728716A3 (ru) | 1980-04-15 |
| BE793978A (fr) | 1973-07-12 |
| DK141201C (enrdf_load_stackoverflow) | 1980-07-28 |
| CH606030A5 (enrdf_load_stackoverflow) | 1978-10-13 |
| CH605959A5 (en) | 1978-10-13 |
| IL41130A0 (en) | 1973-02-28 |
| CH606031A5 (enrdf_load_stackoverflow) | 1978-10-13 |
| DK141201B (da) | 1980-02-04 |
| NL7300518A (enrdf_load_stackoverflow) | 1973-07-17 |
| SE392274B (sv) | 1977-03-21 |
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