GB1378076A - N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid and preparation thereof - Google Patents

N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid and preparation thereof

Info

Publication number
GB1378076A
GB1378076A GB1444772A GB1444772A GB1378076A GB 1378076 A GB1378076 A GB 1378076A GB 1444772 A GB1444772 A GB 1444772A GB 1444772 A GB1444772 A GB 1444772A GB 1378076 A GB1378076 A GB 1378076A
Authority
GB
United Kingdom
Prior art keywords
acid
methoxy
raubasinic
march
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1444772A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omnium Chimique SA
Original Assignee
Omnium Chimique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE764950A external-priority patent/BE764950A/en
Priority claimed from BE780854A external-priority patent/BE780854R/en
Application filed by Omnium Chimique SA filed Critical Omnium Chimique SA
Publication of GB1378076A publication Critical patent/GB1378076A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Abstract

1378076 Basic esters of 11-methoxyraubasinic acid OMNIUM CHIMIQUE SA 28 March 1972 [29 March 1971 17 March 1972] 14447/72 Heading C2C Novel compounds of formula in which R is an alkyl group, preferably containing up to 4 carbon atoms, or the two R groups, together with the nitrogen atom to which they are attached, form a morpholinyl, piperidinyl, piperazinyl or pyrrolidinyl heterocyclic group, and their physiologically acceptable acid addition salts, are prepared from 11- methoxy-raubasinic acid by reaction with a compound (R) 2 NCH 2 CH 2 X where X is halogen or from 11-methoxy-raubasine by transesterification; 11-methoxy-raubasinic acid is prepared from methyl ester (11-methoxyraubasine) by saponification. Pharmaceutical compositions having spasmolytic and hypertensive activity comprise an above novel compound and a carrier.
GB1444772A 1971-03-29 1972-03-28 N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid and preparation thereof Expired GB1378076A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE764950A BE764950A (en) 1971-03-29 1971-03-29 N-disubstd-amino-ethyl esters of 11-methoxy-raubasinic acid
BE780854A BE780854R (en) 1972-03-17 1972-03-17 N-disubstdaminoethyl 11-methoxy raubasinates prepn - - by transesterification from 11-methoxy raubasine
GB1378076 1972-03-28

Publications (1)

Publication Number Publication Date
GB1378076A true GB1378076A (en) 1974-12-18

Family

ID=27159370

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1444772A Expired GB1378076A (en) 1971-03-29 1972-03-28 N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid and preparation thereof

Country Status (1)

Country Link
GB (1) GB1378076A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032889A1 (en) * 1980-01-09 1981-07-29 OMNICHEM Société anonyme 1,10-Dimethyl-oxayohimbane derivatives and medicaments containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032889A1 (en) * 1980-01-09 1981-07-29 OMNICHEM Société anonyme 1,10-Dimethyl-oxayohimbane derivatives and medicaments containing them
EP0032889B1 (en) * 1980-01-09 1984-02-15 OMNICHEM Société anonyme 1,10-dimethyl-oxayohimbane derivatives and medicaments containing them

Similar Documents

Publication Publication Date Title
GB1466646A (en) Substituted benzamides
ES453389A1 (en) Amino-alcohol derivatives and their preparation
GB1285400A (en) Esters of substituted anthranilic acid
GB1369999A (en) Monomethyl-amino-triidobenzene compounds for use as x-ray shading agents
GB1265279A (en)
GB1378076A (en) N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid and preparation thereof
GB1383888A (en) Amino ether derivatives of orthothymatic esters
ES472749A1 (en) N-substituted 2-hydrazono-propionic acid derivatives, process for their preparation and pharmaceutical compositions containing them.
ES450128A1 (en) Behenic acid esters of 9-thiaxanthene propylidene heterocyclic alcohols and their use in pharmaceutical composition
GB1186495A (en) 0-[3-(4-Fluorobenzoyl) Proplyl]-4-Substituted Piperazines, their Acid Addition Salts and their method of preparation
ES8506296A1 (en) Phenothiazine derivatives.
GB1327157A (en) N-acyl-piperazinoalkyl-pyrazoles and their preparation
GB1262052A (en) Dibenzofuran derivatives
ES438834A1 (en) Benzhydryloxyalkylamine derivatives and process for the preparation thereof
EP0036218A3 (en) Quinuclidinic esters and derivatives of phenoxycarboxylic acids, a process for the preparation thereof, and related pharmaceutical compositions
ATE52509T1 (en) THIAZOLIDE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION.
GB1472496A (en) N-di substituted amino ethyl esters of raubasine and process for praparing them
ES445343A1 (en) Quaternary xanthinylalkyl nortropine
ES401174A1 (en) 3-Aryl-5-oxo-2-pyrazoline-4-carboxanilides and process therefor
GB1199040A (en) Diisoeugenol Derivatives
GB1187733A (en) 0,3,10-Berbine Derivatives, their Acid Addition Salts, and Process for the Preparation Thereof
ATE3298T1 (en) 17-AMINO-16-HYDROXY-STEROIDS OF THE ANDROSTANE AND ESTRANE SERIES AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS.
GB1418831A (en) Reserpine derivatives
GB1472344A (en) Methylene dibenzocycloheptanes
GB1433222A (en)

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee