IL40521A - 1-heterocyclyl-3-indolealkanoic acid derivatives - Google Patents
1-heterocyclyl-3-indolealkanoic acid derivativesInfo
- Publication number
- IL40521A IL40521A IL40521A IL4052172A IL40521A IL 40521 A IL40521 A IL 40521A IL 40521 A IL40521 A IL 40521A IL 4052172 A IL4052172 A IL 4052172A IL 40521 A IL40521 A IL 40521A
- Authority
- IL
- Israel
- Prior art keywords
- heterocyclyl
- acid derivatives
- indolealkanoic
- indolealkanoic acid
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1811672A GB1356834A (en) | 1971-11-03 | 1971-11-03 | Indole derivatives |
| GB1811672 | 1972-04-19 | ||
| GB3076772 | 1972-06-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL40521A0 IL40521A0 (en) | 1972-12-29 |
| IL40521A true IL40521A (en) | 1975-06-25 |
Family
ID=27257588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL40521A IL40521A (en) | 1971-11-03 | 1972-10-06 | 1-heterocyclyl-3-indolealkanoic acid derivatives |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3884919A (de) |
| JP (1) | JPS4856667A (de) |
| AR (3) | AR198064A1 (de) |
| BE (1) | BE790679A (de) |
| CA (1) | CA983932A (de) |
| CH (1) | CH577499A5 (de) |
| DD (1) | DD105611A5 (de) |
| DE (1) | DE2253927A1 (de) |
| EG (1) | EG11358A (de) |
| ES (2) | ES408226A1 (de) |
| FR (1) | FR2158464B1 (de) |
| GB (1) | GB1356834A (de) |
| HU (1) | HU169711B (de) |
| IE (1) | IE37998B1 (de) |
| IL (1) | IL40521A (de) |
| NL (1) | NL7214807A (de) |
| SE (1) | SE384856B (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022780A (en) * | 1973-03-06 | 1977-05-10 | Imperial Chemical Industries Limited | Process for the manufacture of indole derivatives |
| FR2421900A1 (fr) * | 1977-03-17 | 1979-11-02 | Sauba Lab | Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques |
| US4316847A (en) * | 1979-07-30 | 1982-02-23 | Hoffmann-La Roche Inc. | Pyrroles and pyrrolidines |
| US4459227A (en) * | 1981-03-02 | 1984-07-10 | Duke University | Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones |
| CZ288955B6 (cs) * | 1994-02-23 | 2001-10-17 | Pfizer Inc. | Substituované chinazolinové deriváty, jejich pouľití a farmaceutické prostředky na jejich bázi |
| US6252084B1 (en) * | 1994-03-15 | 2001-06-26 | Eli Lilly And Company | 1H-indole-3-acetamide sPLA2 inhibitors |
| WO1999043654A2 (en) * | 1998-02-25 | 1999-09-02 | Genetics Institute, Inc. | Inhibitors of phospholipase enzymes |
| US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0200356D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| PT1471057E (pt) | 2003-04-25 | 2006-05-31 | Actimis Pharmaceuticals Inc | Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2 |
| AU2004236239A1 (en) * | 2003-04-30 | 2004-11-18 | The Institutes For Pharmaceutical Discovery, Llc | Substituted heteroaryls as inhibitors of protein tyrosine phosphatases |
| SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
| SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
| ATE433452T1 (de) | 2004-01-31 | 2009-06-15 | Actimis Pharmaceuticals Inc | Imidazoä1,2-cüpyrimidinylessigsäurederivate |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| JP5208510B2 (ja) | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| US8148572B2 (en) | 2005-10-06 | 2012-04-03 | Astrazeneca Ab | Compounds |
| EP2125722A2 (de) | 2006-05-26 | 2009-12-02 | AstraZeneca AB | Biaryl- oder arylheteroaryl-substituierte indole |
| JP5270542B2 (ja) | 2006-07-22 | 2013-08-21 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| JP5524847B2 (ja) | 2007-09-25 | 2014-06-18 | アクチミス ファーマシューティカルズ インコーポレーテッド | Ｃｒｔｈ２アンタゴニストとしてのアルキルチオピリミジン |
| US8314116B2 (en) | 2007-09-25 | 2012-11-20 | Actimis Pharmaceuticals, Inc. | 2-S-benzyl substituted pyrimidines as CRTH2 antagonists |
| ES2442717T3 (es) | 2008-01-18 | 2014-02-13 | Atopix Therapeutics Limited | Compuestos que tienen actividad antagonista de CRTH2 |
| US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| JP2011509990A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
| WO2009093029A1 (en) | 2008-01-22 | 2009-07-30 | Oxagen Limited | Compounds having crth2 antagonist activity |
| GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
| GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| JP2022512588A (ja) * | 2018-10-05 | 2022-02-07 | バーテックス ファーマシューティカルズ インコーポレイテッド | アルファ１アンチトリプシンのモジュレーター |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL125443C (de) * | 1963-06-06 | |||
| US3679692A (en) * | 1969-10-01 | 1972-07-25 | Mead Johnson & Co | Iminomethylindolines |
-
0
- BE BE790679D patent/BE790679A/xx unknown
-
1971
- 1971-11-03 GB GB1811672A patent/GB1356834A/en not_active Expired
-
1972
- 1972-09-28 IE IE1320/72A patent/IE37998B1/xx unknown
- 1972-09-29 CA CA152,944A patent/CA983932A/en not_active Expired
- 1972-10-06 IL IL40521A patent/IL40521A/xx unknown
- 1972-10-10 US US296202A patent/US3884919A/en not_active Expired - Lifetime
- 1972-10-27 AR AR244863A patent/AR198064A1/es active
- 1972-10-29 EG EG446/72A patent/EG11358A/xx active
- 1972-11-02 FR FR7238836A patent/FR2158464B1/fr not_active Expired
- 1972-11-02 SE SE7214215A patent/SE384856B/xx unknown
- 1972-11-02 CH CH1597672A patent/CH577499A5/xx unknown
- 1972-11-02 DD DD166646A patent/DD105611A5/xx unknown
- 1972-11-02 JP JP47110172A patent/JPS4856667A/ja active Pending
- 1972-11-02 NL NL7214807A patent/NL7214807A/xx unknown
- 1972-11-03 DE DE2253927A patent/DE2253927A1/de active Pending
- 1972-11-03 HU HUIE540A patent/HU169711B/hu unknown
- 1972-11-03 ES ES408226A patent/ES408226A1/es not_active Expired
-
1973
- 1973-07-31 AR AR249382A patent/AR203627A1/es active
- 1973-07-31 AR AR249381A patent/AR203626A1/es active
-
1975
- 1975-04-30 ES ES437331A patent/ES437311A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU169711B (de) | 1977-02-28 |
| IL40521A0 (en) | 1972-12-29 |
| CH577499A5 (de) | 1976-07-15 |
| DD105611A5 (de) | 1974-05-05 |
| FR2158464A1 (de) | 1973-06-15 |
| GB1356834A (en) | 1974-06-19 |
| JPS4856667A (de) | 1973-08-09 |
| EG11358A (en) | 1977-02-28 |
| CA983932A (en) | 1976-02-17 |
| AR198064A1 (es) | 1974-05-31 |
| SE384856B (sv) | 1976-05-24 |
| NL7214807A (de) | 1973-05-07 |
| AR203626A1 (es) | 1975-09-30 |
| IE37998L (en) | 1973-05-03 |
| US3884919A (en) | 1975-05-20 |
| BE790679A (fr) | 1973-04-27 |
| IE37998B1 (en) | 1977-12-07 |
| ES437311A1 (es) | 1977-04-01 |
| DE2253927A1 (de) | 1973-05-10 |
| AR203627A1 (es) | 1975-09-30 |
| FR2158464B1 (de) | 1976-07-02 |
| ES408226A1 (es) | 1976-02-01 |
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