IL38614A - Process for the preparation of azetidino(2,3-d)-thiazolines and thiazolidines - Google Patents
Process for the preparation of azetidino(2,3-d)-thiazolines and thiazolidinesInfo
- Publication number
- IL38614A IL38614A IL38614A IL3861472A IL38614A IL 38614 A IL38614 A IL 38614A IL 38614 A IL38614 A IL 38614A IL 3861472 A IL3861472 A IL 3861472A IL 38614 A IL38614 A IL 38614A
- Authority
- IL
- Israel
- Prior art keywords
- treating
- hydrogen
- double bond
- alkyl
- thiazolidine
- Prior art date
Links
- 150000003548 thiazolidines Chemical class 0.000 title 1
- -1 2-substituted thiazoline azetidinones Chemical class 0.000 claims abstract 7
- OGYGFUAIIOPWQD-UHFFFAOYSA-N 1,3-thiazolidine Chemical compound C1CSCN1 OGYGFUAIIOPWQD-UHFFFAOYSA-N 0.000 claims abstract 2
- 229910000761 Aluminium amalgam Inorganic materials 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 229910000033 sodium borohydride Inorganic materials 0.000 claims abstract 2
- 239000012279 sodium borohydride Substances 0.000 claims abstract 2
- 239000001257 hydrogen Substances 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- 150000003949 imides Chemical class 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 2
- 125000002769 thiazolinyl group Chemical group 0.000 claims 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical compound O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 claims 1
- 125000001246 bromo group Chemical group Br* 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000001984 thiazolidinyl group Chemical group 0.000 claims 1
- 125000006000 trichloroethyl group Chemical group 0.000 claims 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 238000005949 ozonolysis reaction Methods 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 238000003797 solvolysis reaction Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US112389A US3862164A (en) | 1971-02-03 | 1971-02-03 | Thiazolidine azetidinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL38614A0 IL38614A0 (en) | 1972-03-28 |
| IL38614A true IL38614A (en) | 1976-02-29 |
Family
ID=22343631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL38614A IL38614A (en) | 1971-02-03 | 1972-01-23 | Process for the preparation of azetidino(2,3-d)-thiazolines and thiazolidines |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US3862164A (enExample) |
| JP (1) | JPS5614115B1 (enExample) |
| AT (1) | AT315837B (enExample) |
| AU (1) | AU461096B2 (enExample) |
| BE (1) | BE778321A (enExample) |
| CA (1) | CA986521A (enExample) |
| CH (2) | CH576984A5 (enExample) |
| CS (2) | CS176199B2 (enExample) |
| DE (1) | DE2205144C3 (enExample) |
| ES (1) | ES399423A1 (enExample) |
| FR (1) | FR2125060A5 (enExample) |
| GB (1) | GB1374486A (enExample) |
| HU (1) | HU164227B (enExample) |
| IE (1) | IE35989B1 (enExample) |
| IL (1) | IL38614A (enExample) |
| NL (1) | NL170004C (enExample) |
| PH (5) | PH11447A (enExample) |
| PL (4) | PL99979B1 (enExample) |
| SE (1) | SE411757B (enExample) |
| SU (2) | SU587866A3 (enExample) |
| YU (3) | YU36530B (enExample) |
| ZA (1) | ZA72364B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1368232A (en) * | 1970-07-31 | 1974-09-25 | Glaxo Lab Ltd | Azetidino-thiazolidine compounds |
| US4267340A (en) * | 1971-06-24 | 1981-05-12 | Fujisawa Pharmaceutical Co., Ltd. | Disulfide substituted oxazetidine derivatives |
| GB1472863A (en) * | 1974-08-15 | 1977-05-11 | Farmaceutici Italia | Intermediates for cephalosporin synthesis |
| GB1468068A (en) * | 1974-10-03 | 1977-03-23 | Farmaceutici Italia | Preparation of cephalosporin precursors |
| CA1136132A (en) * | 1975-02-17 | 1982-11-23 | Teruji Tsuji | Cyclization to form cephem ring and intermediates therefor |
| GB1543048A (en) * | 1976-02-04 | 1979-03-28 | Beecham Group Ltd | 4-mercapto-3-phenoxyacetamido-2-azetidinone |
| US4147699A (en) * | 1976-11-11 | 1979-04-03 | Massachusetts Institute Of Technology | β-Lactam precursors of penicillin and cephalosporin antibiotics |
| GB1576219A (en) * | 1976-12-31 | 1980-10-01 | Connlab Holdings Ltd | Thiazoleneazetidinone derivatives |
| CA1090806A (en) * | 1977-01-10 | 1980-12-02 | Mitsuru Yoshioka | Oxazolines |
| ES2113382T3 (es) * | 1991-02-20 | 1998-05-01 | Meiji Seika Kaisha | Derivados de azetidinona y procedimiento para producir derivados de azetidinona y cefalosporina. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS157620B2 (en) * | 1965-09-10 | 1974-09-16 | Robert B Woodward | Method of 2-oxoazetidino (3,2-d)-thiazolidinmethanecarboxyl acid's esters making |
| BR6915080D0 (pt) * | 1969-06-12 | 1973-03-08 | Lilly Co Eli | Processo para a preparacao de um produto rearranjado de penicilina |
-
1971
- 1971-02-03 US US112389A patent/US3862164A/en not_active Expired - Lifetime
-
1972
- 1972-01-18 IE IE70/72A patent/IE35989B1/xx unknown
- 1972-01-19 ZA ZA720364A patent/ZA72364B/xx unknown
- 1972-01-20 BE BE778321A patent/BE778321A/xx not_active IP Right Cessation
- 1972-01-21 AU AU38173/72A patent/AU461096B2/en not_active Expired
- 1972-01-23 IL IL38614A patent/IL38614A/en unknown
- 1972-01-24 CA CA133018A patent/CA986521A/en not_active Expired
- 1972-01-26 GB GB370872A patent/GB1374486A/en not_active Expired
- 1972-01-26 SE SE7200872A patent/SE411757B/sv unknown
- 1972-01-31 YU YU00217/72A patent/YU36530B/xx unknown
- 1972-02-02 SU SU721743582A patent/SU587866A3/ru active
- 1972-02-02 PL PL1972153242A patent/PL99979B1/pl unknown
- 1972-02-02 PL PL1972193666A patent/PL101586B1/pl unknown
- 1972-02-02 PL PL1972181152A patent/PL94440B1/pl unknown
- 1972-02-02 HU HUEI406A patent/HU164227B/hu unknown
- 1972-02-02 PH PH13248A patent/PH11447A/en unknown
- 1972-02-02 ES ES399423A patent/ES399423A1/es not_active Expired
- 1972-02-02 PL PL1972203155A patent/PL102203B1/xx unknown
- 1972-02-02 AT AT82372A patent/AT315837B/de not_active IP Right Cessation
- 1972-02-03 CS CS7425A patent/CS176199B2/cs unknown
- 1972-02-03 CH CH707675A patent/CH576984A5/xx not_active IP Right Cessation
- 1972-02-03 DE DE2205144A patent/DE2205144C3/de not_active Expired
- 1972-02-03 JP JP1254672A patent/JPS5614115B1/ja active Pending
- 1972-02-03 FR FR7203628A patent/FR2125060A5/fr not_active Expired
- 1972-02-03 CS CS689A patent/CS176183B2/cs unknown
- 1972-02-03 CH CH157572A patent/CH583243A5/xx not_active IP Right Cessation
- 1972-02-03 NL NLAANVRAGE7201446,A patent/NL170004C/xx not_active IP Right Cessation
-
1974
- 1974-11-08 PH PH16496A patent/PH12071A/en unknown
- 1974-11-08 PH PH16497A patent/PH11077A/en unknown
-
1975
- 1975-03-03 PH PH16496A patent/PH12072A/en unknown
- 1975-03-19 SU SU2114600A patent/SU558645A3/ru active
-
1976
- 1976-11-08 PH PH16497A patent/PH18194A/en unknown
-
1979
- 1979-06-16 YU YU01428/79A patent/YU142879A/xx unknown
- 1979-12-10 YU YU02993/79A patent/YU36531B/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL38614A (en) | Process for the preparation of azetidino(2,3-d)-thiazolines and thiazolidines | |
| ES402651A1 (es) | Procedimiento para la preparacion de derivados de la cefa- losperina. | |
| ES399267A1 (es) | Un procedimiento para la preparacion de cefalosporinas. | |
| IL41814A (en) | Process for the production of 2,5-disubstituted-4-chlorothiazoles and certain such new compounds | |
| GB1479711A (en) | Acylureido cephalosporins | |
| ES445348A1 (es) | Un procedimiento para preparar compuestos de 3-aciloximetil-cefem. | |
| GB1314830A (en) | Pharmaceutically useful benzomorphanes and their production | |
| CA1197840A (en) | Penicillin derivatives and process for preparation of the same | |
| IL38613A (en) | Aztidino-] D-3, 2 [T. HTZUKHBHO | |
| ES8601214A1 (es) | Procedimiento para preparar derivados cefemicos | |
| GB1498931A (en) | Tetrahalopentyl ketone derivatives processes for producing them and their conversion to beta-dihaloethenylcyclopropane derivatives | |
| GB1449656A (en) | Cephalosporin derivatives and their preparation | |
| IE40190B1 (en) | New penicillin compounds, their production, and their medicinal use | |
| SE7508880L (sv) | Forfarande for framstellning av penicilliner och cefalosporiner. | |
| IE33571L (en) | Preparation of cephalosporins | |
| IE42051L (en) | Indole derivatives. | |
| ES423024A1 (es) | Procedimiento para la preparacion de derivados de acidos penicilanico y cefalosporanico. | |
| YU335674A (en) | Process for the enzymatic hydrolysis of cephalosporins derived by chemical enlargening of the penicillin g ring and the enzymatic synthesis of semisynthetic cephalosporins | |
| FR2217009A1 (en) | 2-Tetrazole analogs of prostaglandins - with bronchodilatory, antihyperten-sive and gastric secretion inhibiting activity | |
| GB1485488A (en) | Preparation of cephalosporins | |
| GB960896A (en) | Production of penicillins | |
| FR2181506A1 (en) | Penicillin amides - with improved resistance to penicillinase | |
| GB1504589A (en) | Substituted cephalosporin antibiotics | |
| US3499889A (en) | Penicillin derivatives | |
| GB1381442A (en) | Process for the preparation of prostaglandin precursors |