IL35729A - 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL35729A
IL35729A IL35729A IL3572970A IL35729A IL 35729 A IL35729 A IL 35729A IL 35729 A IL35729 A IL 35729A IL 3572970 A IL3572970 A IL 3572970A IL 35729 A IL35729 A IL 35729A
Authority
IL
Israel
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
IL35729A
Other languages
English (en)
Other versions
IL35729A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL35729A0 publication Critical patent/IL35729A0/xx
Publication of IL35729A publication Critical patent/IL35729A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL35729A 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them IL35729A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen

Publications (2)

Publication Number Publication Date
IL35729A0 IL35729A0 (en) 1971-01-28
IL35729A true IL35729A (en) 1974-01-14

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
IL35729A IL35729A (en) 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US3661908A (https=)
BE (1) BE759493A (https=)
BG (2) BG17799A3 (https=)
CA (1) CA926865A (https=)
CH (3) CH567029A5 (https=)
DK (1) DK128781B (https=)
FR (1) FR2073416B1 (https=)
GB (1) GB1321316A (https=)
IE (1) IE34765B1 (https=)
IL (1) IL35729A (https=)
NL (1) NL7017210A (https=)
NO (1) NO129954B (https=)
SE (1) SE377938B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
TWI498332B (zh) * 2006-04-26 2015-09-01 Hoffmann La Roche 作為pi3k抑制劑之嘧啶衍生物及相關製備方法、醫藥組合物、用途、套組及產物
MX2008013578A (es) * 2006-04-26 2009-03-23 Hoffmann La Roche Derivados de tieno [3,2-d]pirimidina utiles como inhibidores de fosfatidilinositol 3-cinasa(p13k).
CN101511840A (zh) * 2006-04-26 2009-08-19 吉宁特有限公司 磷酸肌醇3-激酶抑制剂化合物及其使用方法
WO2008070740A1 (en) * 2006-12-07 2008-06-12 F.Hoffmann-La Roche Ag Phosphoinositide 3-kinase inhibitor compounds and methods of use
ES2571028T3 (es) * 2006-12-07 2016-05-23 Genentech Inc Compuestos inhibidores de fosfoinositida 3-cinasa y métodos de uso
US7893060B2 (en) * 2007-06-12 2011-02-22 F. Hoffmann-La Roche Ag Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
WO2009042607A1 (en) * 2007-09-24 2009-04-02 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
US8354528B2 (en) 2007-10-25 2013-01-15 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CN102369011A (zh) 2009-03-12 2012-03-07 健泰科生物技术公司 用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
CN102459272B (zh) * 2009-05-27 2014-08-06 健泰科生物技术公司 对P110δ具有选择性的为PI3K抑制剂的二环嘧啶化合物和使用方法
CA2772371A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
KR101489045B1 (ko) * 2009-10-12 2015-02-02 에프. 호프만-라 로슈 아게 Ｐｉ3ｋ 억제자 및 ｍｅｋ 억제자의 조합
MX2012011887A (es) 2010-04-16 2012-11-30 Genentech Inc Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
CA2901126C (en) 2013-02-25 2022-01-25 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant

Also Published As

Publication number Publication date
BG17799A3 (bg) 1973-12-25
US3661908A (en) 1972-05-09
CH559210A5 (https=) 1975-02-28
CH568324A5 (https=) 1975-10-31
BG17800A3 (bg) 1973-12-25
SE377938B (https=) 1975-08-04
IL35729A0 (en) 1971-01-28
FR2073416A1 (https=) 1971-10-01
NL7017210A (https=) 1971-05-28
DK128781B (da) 1974-07-01
IE34765L (en) 1971-05-26
NO129954B (https=) 1974-06-17
FR2073416B1 (https=) 1975-04-18
CH567029A5 (https=) 1975-09-30
GB1321316A (en) 1973-06-27
CA926865A (en) 1973-05-22
IE34765B1 (en) 1975-08-06
BE759493A (fr) 1971-05-25

Similar Documents

Publication Publication Date Title
IL35729A (en) 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them
IL36079A0 (en) 4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them
IL39341A (en) Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them
IL35078A (en) 2-aminoalkylamino-thieno (3,2-d) pyrimidines and their salts,their preparation and pharmaceutical compositions containing them
IL35688A (en) Substituted n-allyl-2-arylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
IL33925A0 (en) Acetyl-guanidine derivatives,their preparation and pharmaceutical compositions containing them
IL34173A0 (en) Imidazolidinone derivatives,their preparation and pharmaceutical compositions containing them
IL35689A (en) 2-arylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
IL39173A0 (en) 2-(5-nitro-2-furyl)-thieno(2,3-d)pyrimidines and salts thereof,their preparation and pharmaceutical compositions containing them
IL40800A0 (en) Thiazolo(5,4-d)pyrimidines,their preparation and pharmaceutical compositions containing them
ZA707999B (en) Improvements relating to 2-(5-nitro-2-furyl)-thieno(3,2-d)pyrimidines
IL35434A0 (en) Basically substituted tertiary butanols,their preparation and pharmaceutical compositions containing them
IL35779A (en) 4-amino-quinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL35211A0 (en) 4-aryl-4-hydroxy-piperidine derivatives,their preparation and pharmaceutical compositions containing them
IL34947A0 (en) Pyridobenzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them
IL33821A (en) 1,3-dihydro-5-phenyl or pyridyl-2h-1,4-benzodiazepin-2-onederivatives,their preparation and pharmaceutical compositions containing them
IL34317A0 (en) Substituted acetamides,their preparation and pharmaceutical compositions containing them
IL33993A (en) Aminopropiophenones,their preparation and pharmaceutical compositions containing them
IL33947A0 (en) D-2-(6-substituted-2-naphthyl)propanals,their preparation and pharmaceutical compositions containing them
IL33979A (en) Amidine derivatives,their preparation and pharmaceutical compositions containing them
IL36096A0 (en) 2,6-dimorpholino-pyrimido (5,4-d) pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL33321A (en) Pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL33687A0 (en) Phenyl-thiazole derivatives,their preparation and pharmaceutical compositions containing them
HK67480A (en) 2-amino-4-(2-imidazolyl-vinyl)-pyrimidines, their preparation and use, and pharmaceutical compositions containing them
IL35086A (en) 1-(4-(thieno(2,3-b)(1,5)benzothiazepin-4-yl)-1-piperazinyl)-alkyl-imidazolidin-2-one derivatives,their preparation and pharmaceutical compositions containing them