IL34433A - Synthesis of substituted 2,4-diamino-5-benzylpyrimidine and sulphone intermediates therefor - Google Patents
Synthesis of substituted 2,4-diamino-5-benzylpyrimidine and sulphone intermediates thereforInfo
- Publication number
- IL34433A IL34433A IL34433A IL3443370A IL34433A IL 34433 A IL34433 A IL 34433A IL 34433 A IL34433 A IL 34433A IL 3443370 A IL3443370 A IL 3443370A IL 34433 A IL34433 A IL 34433A
- Authority
- IL
- Israel
- Prior art keywords
- benzylpyrimidine
- sulphone
- diamino
- synthesis
- substituted
- Prior art date
Links
- XHPZVBGIPQQTQW-UHFFFAOYSA-N 5-benzylpyrimidine-2,4-diamine Chemical class NC1=NC(N)=NC=C1CC1=CC=CC=C1 XHPZVBGIPQQTQW-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 125000001174 sulfone group Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2517169 | 1969-05-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL34433A0 IL34433A0 (en) | 1970-07-19 |
| IL34433A true IL34433A (en) | 1971-10-20 |
Family
ID=10223379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL34433A IL34433A (en) | 1969-05-16 | 1970-05-01 | Synthesis of substituted 2,4-diamino-5-benzylpyrimidine and sulphone intermediates therefor |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS505184B1 (OSRAM) |
| AT (1) | AT308082B (OSRAM) |
| BR (1) | BR6915082D0 (OSRAM) |
| CA (1) | CA994812A (OSRAM) |
| CH (1) | CH544071A (OSRAM) |
| DE (1) | DE2023977C2 (OSRAM) |
| ES (3) | ES379700A1 (OSRAM) |
| FI (1) | FI56375C (OSRAM) |
| FR (1) | FR2070070A1 (OSRAM) |
| IL (1) | IL34433A (OSRAM) |
| IT (1) | IT1021507B (OSRAM) |
| NL (2) | NL173395C (OSRAM) |
| PL (1) | PL92440B1 (OSRAM) |
| SE (2) | SE400777B (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1469521A (en) * | 1973-01-05 | 1977-04-06 | Wellcome Found | Antimicrobial preparations |
| US4687861A (en) * | 1984-11-28 | 1987-08-18 | Ciba-Geigy Corporation | Microbicidal compositions |
| PT1725540E (pt) * | 2004-03-05 | 2012-11-29 | Hoffmann La Roche | Diaminopirimidinas como antagonistas de p2x3 e p2x2/3 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3049544A (en) * | 1962-08-14 | Method for the preparation of | ||
| DE1303727B (de) | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-Arylidensubstituierte Propioni-Irile |
| NL122146C (OSRAM) * | 1960-09-02 | |||
| DE1620729A1 (de) | 1965-07-08 | 1970-08-20 | Wellcome Found | Verfahren zur Herstellung von substituierten Benzylpyrimidinen |
| GB1261455A (en) | 1969-03-06 | 1972-01-26 | Burroughs Wellcome Co | Improvements in or relating to substituted acrylonitriles |
-
1969
- 1969-12-12 BR BR215082/69A patent/BR6915082D0/pt unknown
-
1970
- 1970-03-05 PL PL1970177150A patent/PL92440B1/pl unknown
- 1970-03-06 AT AT100472A patent/AT308082B/de active
- 1970-05-01 IL IL34433A patent/IL34433A/xx unknown
- 1970-05-13 FI FI1338/70A patent/FI56375C/fi active
- 1970-05-14 ES ES379700A patent/ES379700A1/es not_active Expired
- 1970-05-15 JP JP45041540A patent/JPS505184B1/ja active Pending
- 1970-05-15 IT IT50715/70A patent/IT1021507B/it active
- 1970-05-15 SE SE7006713A patent/SE400777B/xx unknown
- 1970-05-15 FR FR7017799A patent/FR2070070A1/fr active Granted
- 1970-05-15 NL NLAANVRAGE7007108,A patent/NL173395C/xx not_active IP Right Cessation
- 1970-05-15 DE DE2023977A patent/DE2023977C2/de not_active Expired
- 1970-05-15 CH CH732370A patent/CH544071A/de not_active IP Right Cessation
- 1970-05-19 CA CA083,401A patent/CA994812A/en not_active Expired
-
1972
- 1972-09-15 ES ES406726A patent/ES406726A1/es not_active Expired
- 1972-09-15 ES ES406725A patent/ES406725A1/es not_active Expired
-
1973
- 1973-06-07 SE SE7308030A patent/SE398878B/xx unknown
-
1980
- 1980-08-25 NL NL8004796A patent/NL8004796A/nl not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI56375B (fi) | 1979-09-28 |
| NL173395B (nl) | 1983-08-16 |
| FI56375C (fi) | 1980-01-10 |
| ES379700A1 (es) | 1973-01-16 |
| CH544071A (de) | 1973-11-15 |
| JPS505184B1 (OSRAM) | 1975-02-28 |
| DE2023977A1 (de) | 1971-02-18 |
| BR6915082D0 (pt) | 1973-03-08 |
| ES406725A1 (es) | 1975-10-01 |
| DE2023977C2 (de) | 1984-03-15 |
| FR2070070A1 (en) | 1971-09-10 |
| ES406726A1 (es) | 1975-10-01 |
| SE400777B (sv) | 1978-04-10 |
| NL173395C (nl) | 1984-01-16 |
| AT308082B (de) | 1973-06-25 |
| CA994812A (en) | 1976-08-10 |
| PL92440B1 (en) | 1977-04-30 |
| SE398878B (sv) | 1978-01-23 |
| IT1021507B (it) | 1978-02-20 |
| IL34433A0 (en) | 1970-07-19 |
| FR2070070B1 (OSRAM) | 1974-10-11 |
| NL8004796A (nl) | 1980-11-28 |
| NL7007108A (OSRAM) | 1970-11-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA957684A (en) | Synthesis of 1h-pyrazolo(3,2,-c)-s-triazoles | |
| AR199463A1 (es) | Sintesis de nucleosidos de 1,2,4-triazol-3-sustituidos | |
| IL34400A (en) | 5'-esters of ara-cytidine | |
| JPS5762294A (en) | Manufacture of 5'-o-acyl-ara-cytidines | |
| GB1401944A (en) | Sulphone intermediates | |
| IL35894A (en) | The preparation of 1,2,4-triazine-5-ones and certain novel intermediates being 5-imino-1,2,4-triazine derivatives | |
| CA919701A (en) | Synthesis of 2,4,6-tri-t-butyl-4-methoxycyclohexa-2,5-dien-1-one | |
| IL38145A0 (en) | Substituted semicarbazones of 2',6'-dihalobenzaldehydes and their preparation | |
| IL39221A (en) | The preparation of 2,4-diamino-5-benzyl-pyrimidines and novel 2,4-diamino-6-alkylthio-5-benzyl-pyrimidine intermediates | |
| AU6382073A (en) | Synthesis of %&<-glaziovine | |
| JPS5655352A (en) | Manufacture of novel phenylaminoalkanes | |
| IL34433A0 (en) | Synthesis of substituted 2,4-diamino-5-benzylpyrimidine | |
| BE749038A (fr) | Synthese d'alcadienols | |
| CA929044A (en) | Metal plating of plastics | |
| BE759354A (fr) | Preparation de dihydroxy-1,4-dioxannes | |
| AU443832B2 (en) | Synthesis of urea | |
| AU445647B2 (en) | Preperation of 4,4' di(aminophenyl) methane | |
| BE763249A (fr) | Piece d'horlogerie | |
| CA963905A (en) | Intermediates in the synthesis of 6,7,8-trialkoxy-4-aminoquinazolines | |
| IL39957A (en) | The preparation of l-tyrosine derivatives and some novel intermediates therefor | |
| ZA706818B (en) | Benzopyran-5-ols and coumarin intermediates therefor | |
| CA922312A (en) | Synthesis of tetracyclines | |
| ZA711371B (en) | Production of 1,1'-peroxydicyclohexylamine | |
| IL34384A0 (en) | Derivatives of 2,6-diaminobenzothiazole | |
| IL34503A (en) | The manufacture of tyrosine derivatives |