IL32853A - 5,11-dihydro-6h-pyrido(2,3-b)-(1,4)benzodiazepine-6-ones substituted in 11-position and processes for the production thereof - Google Patents

5,11-dihydro-6h-pyrido(2,3-b)-(1,4)benzodiazepine-6-ones substituted in 11-position and processes for the production thereof

Info

Publication number
IL32853A
IL32853A IL32853A IL3285369A IL32853A IL 32853 A IL32853 A IL 32853A IL 32853 A IL32853 A IL 32853A IL 3285369 A IL3285369 A IL 3285369A IL 32853 A IL32853 A IL 32853A
Authority
IL
Israel
Prior art keywords
dihydro
pyrido
compounds
methyl
group
Prior art date
Application number
IL32853A
Other languages
English (en)
Other versions
IL32853A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL32853A0 publication Critical patent/IL32853A0/xx
Publication of IL32853A publication Critical patent/IL32853A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL32853A 1968-08-20 1969-08-19 5,11-dihydro-6h-pyrido(2,3-b)-(1,4)benzodiazepine-6-ones substituted in 11-position and processes for the production thereof IL32853A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681795183 DE1795183B1 (de) 1968-08-20 1968-08-20 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel

Publications (2)

Publication Number Publication Date
IL32853A0 IL32853A0 (en) 1969-11-12
IL32853A true IL32853A (en) 1972-06-28

Family

ID=5708088

Family Applications (1)

Application Number Title Priority Date Filing Date
IL32853A IL32853A (en) 1968-08-20 1969-08-19 5,11-dihydro-6h-pyrido(2,3-b)-(1,4)benzodiazepine-6-ones substituted in 11-position and processes for the production thereof

Country Status (23)

Country Link
US (2) US3660380A (nl)
AT (1) AT289127B (nl)
BE (1) BE737748A (nl)
BG (1) BG15574A3 (nl)
BR (1) BR6911739D0 (nl)
CH (1) CH511241A (nl)
CS (1) CS163742B2 (nl)
DE (1) DE1795183B1 (nl)
DK (1) DK123600B (nl)
ES (1) ES370394A1 (nl)
FI (1) FI49515C (nl)
FR (1) FR2016009B1 (nl)
GB (1) GB1277132A (nl)
IE (1) IE33269B1 (nl)
IL (1) IL32853A (nl)
IT (1) IT7949451A0 (nl)
MY (1) MY7500209A (nl)
NL (1) NL142683B (nl)
NO (1) NO124073B (nl)
PL (1) PL69767B1 (nl)
RO (1) RO56172A (nl)
SE (1) SE352638B (nl)
YU (1) YU34038B (nl)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI50242C (fi) * 1969-07-18 1976-01-12 Thomae Gmbh Dr K Menetelmä valmistaa farmakologisesti aktiivisia uusia diallyyliaminoal kanoyylidibenso- tai pyridobenso-diatsepiineja ja niiden happoadditios uoloja.
DE2424811C3 (de) * 1974-05-22 1981-08-20 Dr. Karl Thomae Gmbh, 7950 Biberach Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2724434A1 (de) * 1977-05-31 1979-02-22 Thomae Gmbh Dr K Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2724501A1 (de) * 1977-05-31 1978-12-21 Thomae Gmbh Dr K Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6- one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
DE2724478C2 (de) * 1977-05-31 1986-05-22 Dr. Karl Thomae Gmbh, 7950 Biberach 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
NO802326L (no) * 1979-08-03 1981-02-04 Byk Gulden Lomberg Chem Fab Fremgangsmaate ved fremstilling av substituerte tetraazatricyklen
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
US4381301A (en) * 1980-05-07 1983-04-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
DE3113094A1 (de) * 1981-04-01 1982-10-21 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
DE3204401A1 (de) 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DD236731B3 (de) * 1983-10-19 1992-12-10 Dresden Arzneimittel Verfahren zur herstellung von neuen in 5-stellung substituierten 5,10-dihydro-11h-dibenzo|b,e¨|1,4¨diazepin-11-onen
DE3403693A1 (de) * 1984-02-03 1985-08-08 Dr. Karl Thomae Gmbh, 7950 Biberach Verwendung von pirenzepin, seinen salzen bzw. pirenzepinhaltigen arzneimitteln zur behandlung des colon irritabile
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0218678A1 (en) * 1985-04-19 1987-04-22 University Patents, Inc. Method for treating obstructive airway diseases
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
DE3919076A1 (de) * 1989-06-10 1990-12-13 Thomae Gmbh Dr K Mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
US5716952A (en) * 1992-03-18 1998-02-10 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of muscarinic antagonists
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
AU2005263577C1 (en) 2004-07-16 2010-08-26 Proteosys Ag Muscarinic antagonists with PARP and SiR modulating activity as cytoprotective agents
US8748419B2 (en) 2006-06-16 2014-06-10 Theracos, Inc. Treating obesity with muscarinic receptor M1 antagonists
US7893053B2 (en) 2006-06-16 2011-02-22 Theracos, Inc. Treating psychological conditions using muscarinic receptor M1 antagonists
FR2909700B1 (fr) 2006-12-12 2010-10-15 Dalo Freres Soc Ensemble support pour un element de toiture,abri comprenant un tel ensemble support et procede de montage d'un tel abri
BRPI0812849A2 (pt) * 2007-07-02 2014-12-09 Ac Immune Sa Composto ou uma composição farmacêutica, e, métodos para usar um composto, para reduzir a carga de placa b-amilóide e/ou inibir a formação das placas b-amilóides e/ou retardar o aumento da carga amilóide no cérebro de um animal, para tratar uma condição, e, para reter ou aumentar a capacidade de memória cognitiva em um animal
WO2010081825A2 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as an agent in cancer treatment

Also Published As

Publication number Publication date
BR6911739D0 (pt) 1973-05-31
DE1795183B1 (de) 1972-07-20
CS163742B2 (nl) 1975-11-07
US3743734A (en) 1973-07-03
MY7500209A (en) 1975-12-31
NL142683B (nl) 1974-07-15
NO124073B (nl) 1972-02-28
BG15574A3 (bg) 1972-05-20
GB1277132A (en) 1972-06-07
SE352638B (nl) 1973-01-08
CH511241A (de) 1971-08-15
FI49515B (nl) 1975-04-01
BE737748A (nl) 1970-02-20
ES370394A1 (es) 1971-04-16
IE33269L (en) 1970-02-20
FR2016009B1 (nl) 1973-08-10
IE33269B1 (en) 1974-05-01
FI49515C (fi) 1975-07-10
NL6912652A (nl) 1970-02-24
IT7949451A0 (it) 1979-06-18
YU215269A (en) 1978-05-15
US3660380A (en) 1972-05-02
AT289127B (de) 1971-04-13
IL32853A0 (en) 1969-11-12
YU34038B (en) 1978-10-31
DK123600B (da) 1972-07-10
RO56172A (nl) 1974-09-01
PL69767B1 (en) 1973-08-31
FR2016009A1 (nl) 1970-04-30

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