IL32844A - Acid 6 -]) - (- a-amino-P-hydroxypenylacetamide [penicillin and its preparation - Google Patents
Acid 6 -]) - (- a-amino-P-hydroxypenylacetamide [penicillin and its preparationInfo
- Publication number
- IL32844A IL32844A IL32844A IL3284469A IL32844A IL 32844 A IL32844 A IL 32844A IL 32844 A IL32844 A IL 32844A IL 3284469 A IL3284469 A IL 3284469A IL 32844 A IL32844 A IL 32844A
- Authority
- IL
- Israel
- Prior art keywords
- acid
- amino
- group
- hydroxyphenyl
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB40319/68A GB1241844A (en) | 1968-08-23 | 1968-08-23 | Penicillins |
Publications (2)
Publication Number | Publication Date |
---|---|
IL32844A0 IL32844A0 (en) | 1969-11-12 |
IL32844A true IL32844A (en) | 1973-02-28 |
Family
ID=10414312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL32844A IL32844A (en) | 1968-08-23 | 1969-08-18 | Acid 6 -]) - (- a-amino-P-hydroxypenylacetamide [penicillin and its preparation |
Country Status (22)
Country | Link |
---|---|
US (1) | US3674776A (xx) |
BE (1) | BE737848A (xx) |
BR (1) | BR6911795D0 (xx) |
CA (1) | CA1012136B (xx) |
CH (1) | CH542878A (xx) |
CY (1) | CY1081A (xx) |
DE (3) | DE1942693C2 (xx) |
DK (1) | DK127000C (xx) |
ES (1) | ES370756A1 (xx) |
FI (1) | FI50425B (xx) |
FR (1) | FR2016283B1 (xx) |
GB (1) | GB1241844A (xx) |
HK (1) | HK56080A (xx) |
IE (1) | IE33574B1 (xx) |
IL (1) | IL32844A (xx) |
KE (1) | KE3073A (xx) |
MY (1) | MY8100196A (xx) |
NL (1) | NL6912905A (xx) |
OA (1) | OA03164A (xx) |
RO (1) | RO56335A (xx) |
SE (2) | SE383634B (xx) |
YU (1) | YU37168B (xx) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3873521A (en) * | 1970-09-17 | 1975-03-25 | Astra Laekemedel Ab | Esters of {60 -amino penicillins |
US4203972A (en) * | 1971-11-01 | 1980-05-20 | Astra Pharmaceutical Products, Inc. | Penicillin composition |
GB1413516A (en) * | 1972-10-06 | 1975-11-12 | Leo Pharm Prod Ltd | Crystalline pivaloyloxymethal d - -alpha- aminobenzylpenicillinate |
GB1465694A (en) * | 1973-05-15 | 1977-02-23 | Beecham Group Ltd | Preparation of penicillin salts |
US3932386A (en) * | 1973-06-18 | 1976-01-13 | American Home Products Corporation | Sodium 6-(L-aminocyclohexane carboxamido)penicillanic acid |
GB1494902A (en) * | 1974-05-09 | 1977-12-14 | Glaxo Lab Ltd | Penicillins |
US3985747A (en) * | 1974-05-24 | 1976-10-12 | Bristol-Myers Company | Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid |
ES436565A1 (es) * | 1974-06-05 | 1977-04-01 | Bristol Myers Co | Un procedimiento para la preparacion de acidos acetamidope- nicilanicos. |
US3925418A (en) * | 1974-06-19 | 1975-12-09 | Bristol Myers Co | Hemisolvate of D-(-)-2-(p-hydroxyphenyl)glycyl chloride hydrochloride and process |
US3969524A (en) * | 1974-08-13 | 1976-07-13 | Hoffmann-La Roche Inc. | Stable amoxicillin dosage form |
AU8364875A (en) * | 1974-08-21 | 1977-02-10 | Hoffmann La Roche | Choline and n-methyl-d-glucamine salts of amoxycillin |
GB1463563A (en) * | 1974-10-10 | 1977-02-02 | Beecham Group Ltd | Pharmaceutical compositions |
GB1523278A (en) * | 1974-10-21 | 1978-08-31 | Gist Brocades Nv | Penicillanic acid derivatives |
JPS5186116A (en) * | 1975-01-20 | 1976-07-28 | Takeda Chemical Industries Ltd | Dd arufua isobuchirusuruhobenjirupenishirinhanyobaiwabutsuketsushono seizoho |
GB1532993A (en) * | 1975-03-07 | 1978-11-22 | Beecham Group Ltd | Injectable antibiotic compositions |
GB1578337A (en) * | 1976-05-13 | 1980-11-05 | Beecham Group Ltd | Amoxycillin composition |
GB1527557A (en) * | 1976-07-07 | 1978-10-04 | Beecham Group Ltd | Process for preparing solid sodium amoxycillin |
GB1576731A (en) * | 1976-08-10 | 1980-10-15 | Beecham Group Ltd | Process for the preparation of sodium amoxycillin |
JPS5736298Y2 (xx) * | 1977-06-27 | 1982-08-11 | ||
NZ189945A (en) * | 1978-04-01 | 1981-04-24 | Beecham Group Ltd | Ampicillin phthalidyl ester naphthalene 2-sulphonate also pharmaceutical compositions |
US4240960A (en) * | 1979-03-19 | 1980-12-23 | Bristol-Myers Company | Trimethylsilyl substituted penicillins |
US4278600A (en) * | 1979-03-19 | 1981-07-14 | Bristol-Myers Company | Production of penicillins |
US4310458A (en) * | 1979-03-19 | 1982-01-12 | Bristol-Myers Company | Production of penicillins |
US4351766A (en) * | 1979-07-12 | 1982-09-28 | Bristol-Myers Company | Production of penicillins |
IE51516B1 (en) * | 1980-10-06 | 1987-01-07 | Leo Pharm Prod Ltd | 1,1-dioxapenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate napsylate |
KR820001564B1 (ko) * | 1981-05-09 | 1982-09-02 | 동신제약 주식회사 | 새로운 실릴화제를 이용한 세팔로스포린 유도체의 제조방법 |
DE3474023D1 (en) * | 1983-06-10 | 1988-10-20 | Beecham Group Plc | Crystalline amoxycillin salt |
JPS6248655A (ja) * | 1985-08-27 | 1987-03-03 | Kanegafuchi Chem Ind Co Ltd | N−〔1(s)−エトキシカルボニル−3−フエニルプロピル〕−l−アラニルクロリド無機酸塩及びその製造法 |
JPS6379888A (ja) * | 1986-09-24 | 1988-04-09 | Tanabe Seiyaku Co Ltd | ペニシリン誘導体の安定型水和物 |
GB9408117D0 (en) | 1994-04-23 | 1994-06-15 | Smithkline Beecham Corp | Pharmaceutical formulations |
AT412213B (de) * | 2000-05-30 | 2004-11-25 | Sandoz Ag | Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte |
JP5113978B2 (ja) * | 2003-11-21 | 2013-01-09 | 味の素株式会社 | グルタミン酸誘導体の有機アミン塩及びその利用 |
US7935377B2 (en) * | 2004-06-04 | 2011-05-03 | Ajinomoto Co., Inc. | Crystals of free (2R, 4R)-monatin and use thereof |
FI20105572A0 (fi) | 2010-05-24 | 2010-05-24 | Prevab R Lcc | Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt |
RU2678124C2 (ru) | 2014-04-17 | 2019-01-23 | Синтесик Байолоджикс, Инк. | Бета-лактамазы с улучшенными свойствами для лечения |
CN106574273B (zh) | 2014-08-28 | 2021-07-02 | 合成生物制品有限公司 | β-内酰胺酶的基于大肠杆菌的生产 |
WO2016057744A1 (en) | 2014-10-08 | 2016-04-14 | Synthetic Biologics, Inc. | Beta-lactamase formulations and uses thereof |
EP3236993B1 (en) | 2014-12-23 | 2023-09-13 | Theriva Biologics, Inc. | Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics |
CN104650119B (zh) * | 2015-02-10 | 2017-04-05 | 中国科学院长春应用化学研究所 | 一种β‑内酰胺化合物的制备方法 |
WO2016137993A1 (en) | 2015-02-23 | 2016-09-01 | Synthetic Biologics, Inc. | Carbapenemases for use with antibiotics for the protection of the intestinal microbiome |
AU2016229976B2 (en) | 2015-03-06 | 2021-11-11 | Theriva Biologics, Inc. | Safe and effective beta-lactamase dosing for microbiome protection |
CN116735514B (zh) * | 2023-08-11 | 2023-11-03 | 昆明理工大学 | 纳米酶结合液液微萃取快速检测天麻硫熏标志物的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2985648A (en) * | 1958-10-06 | 1961-05-23 | Doyle Frank Peter | Alpha-aminobenzylpenicillins |
DE1156078C2 (de) * | 1960-08-25 | 1973-10-25 | Beecham Res Lab | Verfahren zur Herstellung von D(-)-ª‡-Aminobenzylpenicillin und von L(+)-ª‡-Aminobenzylpenicillin |
FR1332557A (fr) * | 1962-03-15 | 1963-07-19 | Bristol Myers Co | Procédé de fabrication d'alpha-amino-benzylpénicillines |
NL299897A (xx) * | 1962-11-02 | |||
GB991586A (en) * | 1963-02-28 | 1965-05-12 | Beecham Res Lab | Process for the preparation of penicillins |
-
1968
- 1968-08-23 GB GB40319/68A patent/GB1241844A/en not_active Expired
-
1969
- 1969-08-18 US US851062A patent/US3674776A/en not_active Expired - Lifetime
- 1969-08-18 SE SE6911472A patent/SE383634B/xx unknown
- 1969-08-18 IE IE1172/69A patent/IE33574B1/xx unknown
- 1969-08-18 IL IL32844A patent/IL32844A/en unknown
- 1969-08-20 CY CY1081A patent/CY1081A/xx unknown
- 1969-08-21 DK DK449169A patent/DK127000C/da not_active IP Right Cessation
- 1969-08-21 DE DE1942693A patent/DE1942693C2/de not_active Expired
- 1969-08-21 DE DE1967313A patent/DE1967313C2/de not_active Expired
- 1969-08-21 DE DE1967083A patent/DE1967083C2/de not_active Expired
- 1969-08-22 RO RO60866A patent/RO56335A/ro unknown
- 1969-08-22 BR BR211795/69A patent/BR6911795D0/pt unknown
- 1969-08-22 FI FI2446/69A patent/FI50425B/fi active
- 1969-08-22 FR FR6928824A patent/FR2016283B1/fr not_active Expired
- 1969-08-22 ES ES370756A patent/ES370756A1/es not_active Expired
- 1969-08-22 BE BE737848D patent/BE737848A/xx not_active IP Right Cessation
- 1969-08-22 NL NL6912905A patent/NL6912905A/xx unknown
- 1969-08-22 CH CH1280969A patent/CH542878A/de not_active IP Right Cessation
- 1969-11-06 OA OA53775A patent/OA03164A/xx unknown
-
1974
- 1974-04-19 SE SE7405340A patent/SE432525B/xx not_active IP Right Cessation
-
1975
- 1975-12-05 YU YU3087/75A patent/YU37168B/xx unknown
-
1976
- 1976-09-28 CA CA262,207A patent/CA1012136B/xx not_active Expired
-
1980
- 1980-08-15 KE KE3073A patent/KE3073A/xx unknown
- 1980-10-02 HK HK560/80A patent/HK56080A/xx unknown
-
1981
- 1981-12-30 MY MY196/81A patent/MY8100196A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE432525B (sv) | 1984-04-09 |
HK56080A (en) | 1980-10-10 |
FR2016283A1 (xx) | 1970-05-08 |
YU37168B (en) | 1984-08-31 |
KE3073A (en) | 1980-08-29 |
BE737848A (xx) | 1970-02-25 |
DE1967313C2 (de) | 1986-05-28 |
NL6912905A (xx) | 1970-02-25 |
GB1241844A (en) | 1971-08-04 |
MY8100196A (xx) | 1981-12-31 |
CA1012136B (en) | 1977-06-14 |
OA03164A (fr) | 1970-12-15 |
YU308775A (en) | 1983-04-27 |
DE1967083C2 (de) | 1986-10-02 |
ES370756A1 (es) | 1971-07-01 |
DK127000C (da) | 1983-02-28 |
IL32844A0 (en) | 1969-11-12 |
US3674776A (en) | 1972-07-04 |
DE1942693C2 (de) | 1984-03-08 |
DE1942693A1 (de) | 1970-02-26 |
CH542878A (de) | 1973-10-15 |
IE33574B1 (en) | 1974-08-21 |
CY1081A (en) | 1980-12-27 |
DK127000B (da) | 1973-09-10 |
FI50425B (xx) | 1975-12-01 |
BR6911795D0 (pt) | 1973-01-11 |
DE1967083A1 (de) | 1977-03-17 |
RO56335A (xx) | 1974-11-11 |
SE383634B (sv) | 1976-03-22 |
FR2016283B1 (xx) | 1974-08-09 |
IE33574L (en) | 1970-02-23 |
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