IL32378A - Process for the preparation of A9-fluoro-61-methylene-prednisolone or prednisone, and their 12 esters - Google Patents

Process for the preparation of A9-fluoro-61-methylene-prednisolone or prednisone, and their 12 esters

Info

Publication number
IL32378A
IL32378A IL32378A IL3237869A IL32378A IL 32378 A IL32378 A IL 32378A IL 32378 A IL32378 A IL 32378A IL 3237869 A IL3237869 A IL 3237869A IL 32378 A IL32378 A IL 32378A
Authority
IL
Israel
Prior art keywords
methylene
fluoro
prednisolone
prednisone
preparing
Prior art date
Application number
IL32378A
Other languages
English (en)
Hebrew (he)
Other versions
IL32378A0 (en
Original Assignee
Merck Ag E
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681793318 external-priority patent/DE1793318C3/de
Application filed by Merck Ag E filed Critical Merck Ag E
Publication of IL32378A0 publication Critical patent/IL32378A0/xx
Publication of IL32378A publication Critical patent/IL32378A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL32378A 1968-08-31 1969-06-11 Process for the preparation of A9-fluoro-61-methylene-prednisolone or prednisone, and their 12 esters IL32378A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681793318 DE1793318C3 (de) 1968-08-31 Verfahren zur Herstellung von 9 a-Fluor-16methylen-prednisolon bzw. -prednison und 21-Estern derselben

Publications (2)

Publication Number Publication Date
IL32378A0 IL32378A0 (en) 1969-08-27
IL32378A true IL32378A (en) 1972-10-29

Family

ID=5707659

Family Applications (1)

Application Number Title Priority Date Filing Date
IL32378A IL32378A (en) 1968-08-31 1969-06-11 Process for the preparation of A9-fluoro-61-methylene-prednisolone or prednisone, and their 12 esters

Country Status (13)

Country Link
US (1) US3684800A (en, 2012)
AT (1) AT310956B (en, 2012)
BE (1) BE738086A (en, 2012)
BR (1) BR6910529D0 (en, 2012)
CH (1) CH521333A (en, 2012)
CS (1) CS172308B2 (en, 2012)
DK (1) DK125244B (en, 2012)
ES (1) ES371022A1 (en, 2012)
FR (1) FR2016708A1 (en, 2012)
GB (1) GB1213118A (en, 2012)
IL (1) IL32378A (en, 2012)
NL (1) NL6908358A (en, 2012)
SE (1) SE351846B (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207235A (en) * 1979-01-12 1980-06-10 Syntex (U.S.A.) Inc. Selective epoxidation of steroidal bromohydrins
CN101125877B (zh) * 2007-09-10 2011-04-06 浙江仙琚制药股份有限公司 甲基泼尼松龙醋酸酯的制备方法
CN102061320B (zh) * 2010-12-02 2013-04-03 浙江仙琚制药股份有限公司 11α，17α-二羟基-雄甾-4-烯-3，20-二酮的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3321496A (en) * 1960-11-17 1967-05-23 Merck & Co Inc 16alpha-halo methyl-saturated steroids of the pregnane series
US3376294A (en) * 1961-04-26 1968-04-02 Pfizer & Co C 6-fluoro-16-methylene steroid compounds and process
DE1251758B (de) * 1965-03-23 1967-10-12 E Merck Aktiengesellschaft, Darmstadt Verfahien zur Herstellung von 6a, 9a-Difluor- 16 methylen 1 4 pregnadien 11/?, 17a d'ol 3 20 dion

Also Published As

Publication number Publication date
BR6910529D0 (pt) 1973-03-13
FR2016708A1 (en, 2012) 1970-05-08
BE738086A (en, 2012) 1970-03-02
IL32378A0 (en) 1969-08-27
DE1793318B2 (de) 1976-12-30
CH521333A (de) 1972-04-15
GB1213118A (en) 1970-11-18
ES371022A1 (es) 1971-12-16
CS172308B2 (en, 2012) 1976-12-29
SE351846B (en, 2012) 1972-12-11
NL6908358A (en, 2012) 1970-03-03
US3684800A (en) 1972-08-15
DK125244B (da) 1973-01-22
DE1793318A1 (de) 1972-03-02
AT310956B (de) 1973-10-25

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